Moderator: Anne Pavy-Le Traon (Toulouse, France)

Guests: Giovanna Calandra-Buonaura (Bologna, Italy) and Valeria Iodice (London, United Kingdom) 

In this week’s podcast episode Anne Pavy-Le Traon hosts two guests, Giovanna Calandra Buonaura and Valeria Iodice, as they discuss a hot topic related to Phenoconversion in Pure Autonomic Failure (PAF). They highlight the natural history of PAF and the importance of recognising this disease as a possible prodromal/ premotor phase of other alpha synucleinopathies. They discuss novel clinical and multimodal biomarkers in early diagnosis of these disorders.