2023 marks 30 years since the very first MS disease-modifying therapy received FDA approval. To say that changed everything would be an understatement.

Two of the top MS experts in the world have published a reflection, looking back at how MS research and treatment has progressed over the past 30 years and looking ahead at the challenges that remain in solving the riddle of MS. Joining me this week are the authors of that reflection, Dr. Fred Lublin and Dr. Stephen Krieger.

Dr. Lublin participated in the development of the very first disease-modifying therapy approved for treating MS and, since that time, he has been involved in the development of nearly all of the DMTs available today. 

Dr. Krieger has developed a game-changing theory that MS is a single disease that evolves along a continuum, rather than the four separate categories that neurologists have used to describe MS for the past couple of decades.

We'll also introduce you to The Community Review of MS Research Committee.

We'll share what very well may be the single most important development to come out of the Pathways To Cures Global Summit.

We'll tell you about the outcome of a study that may point to a potential MS treatment for women that has also been shown to trigger myelin repair.

We'll explain the method for accurately measuring remyelination that was just recently confirmed by a UCSF research team.

And we'll tell you where you can catch the video replay of the webcast that was live-streamed from last month's International Progressive MS Alliance Scientific Congress.

We have a lot to talk about! Are you ready for RealTalk MS??!

I'm back from the Community Review of MS Research Committee meeting  :22

This Week: 30 Years Later....looking back (and ahead!)  4:08

The first-ever Global Research Strategy Framework has been announced   5:26

Don't miss the video replay of the webcast that was live streamed from last month's International Progressive MS Alliance Scientific Congress  2:55

A study shows that the hormone estriol reduces MS severity and promotes myelin repair   9:54

A UCSF research team has developed a method of accurately measuring remyelination   13:16

Dr. Fred Lublin and Dr. Stephen Krieger review the progress that's been made since the approval of the first MS disease-modifying therapy and they look ahead at the challenges that remain in solving the riddle of MS   17:23

Share this episode  30:08

Have you downloaded the free RealTalk MS app???  30:27

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LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

RealTalk MS Episode 297: The Pathways To Cures Global Summit (Part 1) https://realtalkms.com/297

RealTalk MS Episode 298: The Pathways To Cures Global Summit (Part 2) https://realtalkms.com/298

Video Replay: Ending MS Progression: Research Advances That Could Lead to Breakthrough Treatment https://www.youtube.com/watch?v=p9OQ_hvVpfA

STUDY: Neuroprotection in Cerebral Cortex Induced by the Pregnancy Hormone Estriol https://sciencedirect.com/science/article/pii/S0023683723001320?via%3Dihub

RealTalk MS Episode 189: Research on Sex Differences in MS Leads to Potential Treatment Options with Dr. Rhonda Voskuhl https://realtalkms.com/189

STUDY: MWF of the Corpus Callosum Is a Robust Measure of Remyelination: Results from the ReBUILD Trial https://pnas.org/doi/10.1073/pnas.2217635120

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RealTalk MS Episode 305 Guests: Dr. Fred Lublin and Dr. Stephen Krieger

Tags: MS, MultipleSclerosis, MSResearch, MSSociety, RealTalkMS

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