Let's get to know the second generation antidepressants, otherwise known as receptor selective antidepressants. These antidepressants started in the 1980s with the newest one coming out just last year. They tend to only mingle with one or two receptors and have much lower adverse effects than the MAOis and TCAs. They are what most of us think about when we think about antidepressants. In this episode we do an overview of them from FDA approved uses to off label uses. And at the end a little bonus content. I talk about contraindications of the TCAs which I missed in the last episode.