In this episode, we delve into the intriguing world of Cameron lesions, a medical condition first identified in 1986. We explore what these lesions are, their causes, how they are diagnosed, and treatment options. This episode is a deep dive into the intricacies of medical diagnostics and highlights the importance of detailed observation in the field of gastroenterology.

Key Points Discussed:

1. Introduction to Cameron Lesions: Understanding what Cameron lesions are and their association with hiatal hernia.
2. Historical Background: The discovery of Cameron lesions by Cameron and Higgins in the 1980s and their relevance in patients with a portion of the stomach above the diaphragm.
3. Causes of Cameron Lesions: Exploring mechanical trauma, friction at the level of constriction, and other contributing factors like pressure differences during respiration and gastric acid.
4. Prevalence and Diagnosis: Discussing the prevalence of Cameron lesions in patients with hiatal hernias and the role of esophagogastroduodenoscopy (EGD) in diagnosis.
5. Challenges in Diagnosis: Understanding why Cameron lesions are often missed in initial EGDs and the importance of special attention during examinations.
6. Treatment Options: The mainstay of treatment with proton-pump inhibitors (PPIs) and the necessity of iron supplementation.
7. Conclusion: Emphasizing the significance of Cameron lesions in patients with large hiatal hernias and the need for a high index of suspicion among endoscopists.

Recommended Resources:

• https://endocollab.com/blogs/gi-endoscopy-tips-tricks/cameron-lesions
• https://www.thepracticingendoscopist.com/p/cameron-lesions

Timestamps:

- 00:00 Introduction to Cameron Lesions
- 00:12 Definition and Association with Hiatal Hernia
- 00:29 Discovery and Prevalence
- 01:09 Causes of Cameron Lesions
- 02:01 Diagnosis and Challenges
- 02:37 Treatment and Management
- 02:55 Association with Iron Deficiency Anemia and GERD
- 03:05 Significance and Importance of Cameron Lesions
- 03:26 Conclusion

Keywords:
Cameron lesions, hiatal hernia, gastric mucosal folds, mechanical trauma, local ischemia, mucosal stress, ulceration, EGD, proton pump inhibitors, iron deficiency anemia, GERD, size, overlooked, high index of suspicion

https://www.gastroendopod.com

In this episode of the Gastroenterology and Endoscopy Podcast, we explore the world of water-assisted colonoscopy (WAC). WAC is a technique that uses water instead of air or gas during the insertion phase of a colonoscopy, offering numerous benefits for both endoscopists and patients. By utilizing water's natural properties, WAC can reduce pain and discomfort, straighten out the colon, and enhance visibility of the mucosal surface. This technique not only improves patient comfort but also plays a crucial role in colorectal cancer prevention by improving adenoma detection rates. Join us as we delve into the advantages of WAC over traditional methods and its potential impact in the field of gastroenterology.

Quotes

• 00:00:46 - "Studies have shown that water assisted colonoscopies can significantly reduce the pain associated with colonoscopy."
• 00:03:35 - "To sum up, water is not just an alternative for colon distension in colonoscopy, it's an essential component that significantly elevates the effectiveness of the procedure."

Resources

• Water Assisted-Colonoscopy (WAC or Hydrocolonoscopy)
• Do You Use CO2 and Water Immersion in Diagnostic Colonoscopies on a Daily Basis?

Keywords
water-assisted colonoscopy, WAC, hydrocolonoscopy, benefits, endoscopists, patients, concept, application, water, air, gas, insertion phase, colonoscopy, pain, challenging cases, colonoscope, bends, loops, straightening, angulations, gravitational effect, colonic elongation, loop formation, discomfort, sedation, water irrigation, visibility, mucosal surface, adenomas, precancerous growths, ADR, colorectal cancer prevention, air insufflation, water immersion, water exchange, duration, modified version, partial WAC, CO2, combination, tight angulations, colon elongation, cleaning, lumen, folds, polyp detection, modern colonoscopes, water jets, hybrid technique, suction, liberal use, overall quality, water, cleaning, mucosal surface, colonoscopy, debris

https://www.gastroendopod.com

In this episode of the Gastroenterology and Endoscopy podcast, we discuss a challenging case involving a pedunculated duodenal adenoma. These types of polyps present unique challenges for endoscopists, requiring meticulous planning for a successful procedure. The goal is to achieve a complete R0 resection, removing the entire lesion without leaving any microscopic remnants. We explore strategies to prevent migration of the polyp into the bowel, such as positioning the patient in a decubitus supine position or using an antimotility agent. The endoscopist and assistant must be on high alert to catch the polyp with the snare, and having a Roth's net on standby is recommended.

Chapters:
[00:02:16] Preventing complications.

[00:04:10] Preparation is key.

Resources:

1. Endoscopic Resection of Complex Duodenal Polyps
2. Duodenal Polyp Resources on EndoCollab

Quotes:

• 00:02:52 - "By allowing the neoplasm to float, we reduce the chances of transmitting electrosurgical current to the base of the lesion, minimizing the risk of perforation."
• 00:03:06 - "And when it comes to closing the wound post-resection, clips are a must."

Topics Discussed:

1. Introduction to Pedunculated Duodenal Adenoma: Brief description of the polyp’s location and importance of meticulous planning for resection.
2. Achieving Complete Resection (R0): Importance of removing the entire lesion and considerations to make during resection.
3. Preventing Polyp Migration: Strategies to prevent the polyp from moving into the distal bowel.
4. Complication Prevention: Discussion on measures to prevent complications during and after endoscopic resection.
5. Tools and Techniques: Exploration of various tools (snare, Roth’s net, distal transparent cap) and techniques (submucosal injection, underwater resection, use of endoloops and clips).
6. Managing Immediate and Delayed Bleeding: Importance of using endoscopic clips and hemostatic hydrogels, especially in patients on anticoagulation.
7. Proximity to the Papilla of Vater: Ensuring correct identification of the lesion’s location and planning the resection accordingly.
8. Post-procedure Care: Importance of starting proton pump inhibitors post-procedure.
9. Final Thoughts and Goodbye: Summing up the key takeaways from the episode and bidding farewell to the listeners.

Keywords:
Gastroenterology, Endoscopy, pedunculated duodenal adenoma, endoscopic procedures, complications,closing the wound, post-resection, clips, duodenal endoscopic resections, bleeding complications, hemostatic hydrogels, Puristat, anticoagulation, proton pump inhibitors, healing process, polyp's proximity, papilla of vater, ampullary lesion, resection, side-viewing endoscope, complete R0 resection, pedunculated duodenal adenomas, preparation, plan, outcome, patient, insightful, helpful, practice

https://www.gastroendopod.com

In this episode, we discuss the importance of improving colonoscopy prep and achieving better Boston bowel preparation scores. Colon cancer is the second leading cause of cancer death in the US, but it is preventable through colonoscopies. However, the success of a colonoscopy relies heavily on proper bowel preparation. Inadequate prep can decrease polyp detection rates by 27%. Patients are advised to follow a special diet and take a bowel cleansing solution prior to the procedure to ensure a clear view of the colon. The cleanliness of the colon is graded using the Boston Bowel Preparation Scale, with a minimum score of 6 recommended for optimal polyp detection. Unfortunately, the endoscopy center discussed in the episode noticed alarmingly low Boston prep scores among their patients.

Quotes:

• 00:00:29 - "They allow doctors to have a clear view of the entire colon, catching precancerous polyps before they develop into cancer."
• 00:04:13 - "The results of these changes have been nothing short of transformative."

Chapters:
[00:01:45] Importance of Boston bowel preparation.
[00:04:25] Thorough colonoscopy PrEP is indispensable.

Read more: 

• Improving Colonoscopy Prep and Achieving Better Boston Bowel Preparation Scores
• Can I have your experience with colonoscopy prep? I have noticed that most of the patients we receive don't have a good Boston score?
  
  

Keywords:
colonoscopy prep, Boston bowel preparation scores, colon cancer, colonoscopies, bowel preparation, nurses, split-dose bowel preparation regimen, PrEP solution

https://www.gastroendopod.com

In this episode we discuss using natural color changes called "biologic chromoendoscopy" to detect challenging flat colorectal lesions.

Key Topics Discussed:
- While sessile and pedunculated polyps are easy to spot endoscopically, flat and serrated lesions are challenging
- AI, virtual chromoendoscopy, and dyes aren't reliable for flat lesions obscured by mucus/debris
- Mucus changes light penetration, traps stool, and creates a hazy appearance
- Two mucin secretion changes: lost O-acetyl groups and increased sialylation
- "Chicken skin mucosa" refers to white spots from lipid-laden macrophages linked to adenomas, cancer, and juvenile polyps
- Melanosis coli is dark pigmentation from lipofuscin deposits due to chronic laxative use
- Recognizing subtle color changes is critical for finding precancerous flat lesions
- Human eye notices what AI systems miss when looking for discolored tissue

Key Quotes:
- "I call the lesions' natural color changes 'biologic chromoendoscopy.'"
- "Other examples are 'chicken skin mucosa' and melanosis coli."
- "Recognizing these subtle color changes is critical for finding precancerous flat lesions."

Links:
Biologic Chromoendoscopy – The Eye Beats Artificial Intelligence

References Made:
- Mucin secretion changes in serrated lesions
- Melanosis coli and anthraquinone laxative use
- Chicken skin mucosa first described in Japan 

Keywords:
- colorectal cancer screening
- colonoscopy  
- endoscopy
- polyp detection
- flat lesions
- sessile serrated lesions
- biologic chromoendoscopy
- natural chromoendoscopy
- chicken skin mucosa
- melanosis coli
- mucin secretion
- AI in endoscopy
- virtual chromoendoscopy
- chromoendoscopy techniques
- lipofuscin
- precancerous polyps
- colorectal polyps
- anthraquinone laxatives
- visual characterization of lesions
- hazy lesions
- discolored lesions

https://www.gastroendopod.com

Episode Overview:
In this episode, host Dr. Alan Smith discusses a new hybrid endoscopic technique that combines aspects of ESD and EMR to improve resection of difficult to remove gastrointestinal lesions.

Key Topics Covered:
- Limitations of traditional endoscopic resection techniques like ESD and EMR
- Overview of the ESD-EMR hybrid technique (also called pre-cutting EMR)
- Step-by-step explanation of how the hybrid technique works
- Types of challenging GI lesions the hybrid technique is useful for
- Benefits of the ESD-EMR approach over standard resection methods
- Limitations and alternatives to the hybrid technique

Episode Highlights:
- Laterally spreading colorectal lesions often cannot be fully resected with standard EMR snares due to slippery mucosa, leading to recurrence. The ESD-EMR hybrid technique creates a pre-cut groove around the lesion that enables complete en bloc snare resection.
- Serrated polyps in the colorectum frequently evade polypectomy snares because of their subtle mucosal surfaces. The hybrid technique overcomes this with circumferential pre-cutting to allow complete snare capture. 
- For difficult to resect subepithelial tumors like lipomas, the combined ESD-EMR approach facilitates resection of larger lesions compared to standard EMR.
- The hybrid technique decreases recurrence rates and lowers perforation risks versus ESD in less experienced hands.

Notable Quotes:
"But ESD and EMR have limitations resecting certain flat, slippery lesions. Laterally spreading colorectal polyps often slip out of EMR snares, causing incomplete removal and recurrence."

"Making a customized groove around the lesion enables complete snare capture and resection of even challenging flat lesions."

"While limitations exist, this innovative ESD-EMR hybrid strategy expands the range of lesions treatable by endoscopic resection while minimizing recurrence and perforation risks."

Sources:

1. https://endocollab.com/blogs/news/the-esd-emr-hybrid-technique-for-improved-endoscopic-resection
2. https://www.thepracticingendoscopist.com/p/the-esd-emr-hybrid-or-pre-cutting

Topics mentioned:
Endoscopy, ESD, EMR, endoscopic resection, endoscopic submucosal dissection, endoscopic mucosal resection, hybrid technique, pre-cutting, GI tumors, GI lesions, laterally spreading tumors, colorectal polyps, serrated polyps, adenomas, subepithelial tumors, lipomas, en bloc resection, snare resection, electrosurgery, submucosal injection, submucosal dissection, polypectomy, recurrence prevention, non-lifting lesions, fibrotic tumors, gastroenterology

https://www.gastroendopod.com

In the latest episode of the Gastroenterology & Endoscopy Podcast we explore the innovative realm of Hemoclips, or Through-The-Scope-Clips, and their pivotal role in enhancing endoscopic procedures. Initially designed for hemostasis, these multifaceted tools have now widened their scope, proving to be indispensable in a variety of clinical scenarios.

Hemoclips
Hemoclips, now often referred to as "clips", have seen their application extend beyond their original purpose of hemostasis. They are now employed for a range of uses including closing perforations, post-resection defects, marking, and attaching devices like stents and feeding tubes. For instance, during procedures involving gastric, esophageal, or colon perforation, clips can effectively seal the defect, averting further complications. This adaptation of clips over time truly signifies a leap in medical innovation.

Understanding the Anatomy and Deployment of Clips:
Grasping the anatomy and the mechanisms governing the deployment of clips is essential for their effective utilization. A typical clip comprises a stem with two arms with distal teeth. The design might vary; for instance, the arms' shape and number could differ, and so can the length of the stem. This length variation affects their use in narrow areas like small bowel strictures or esophageal stenosis. For example, a longer stem in a small bowel stricture could exacerbate the condition by rubbing against the mucosa on the opposite side. It’s imperative that we understand the anatomy to ensure the appropriate selection and use of these clips.

Advancing and Applying Clips with Precision:
The advancement and application of these Through-The-Scope clips demand precision and care. When initially advancing the clip into the working channel of the scope, it's crucial to hold close to the tip to prevent bending the arm. Once the clip has navigated through the working channel and reaches the tip of the scope, it should be gently pushed out, opened, and pulled back towards the scope. For example, when addressing a bleeding lesion, the clip should be open and advanced towards the lesion by moving the endoscope. And at that pivotal moment, when the clip is near the target vessel or defect to be closed, it should be pushed out with the hand, then closed and released by the assistant. This meticulous handling and application of clips can significantly bolster patient outcomes.

Mastering the Use of Clips:
The art of mastering the use of clips lies in a thorough understanding of their anatomy, their mechanics, and the knack of deploying them accurately, and applying them with precision. It's a journey of practice and learning that unveils the full potential of these versatile tools, thereby elevating patient care to new heights.

Links / References:

• EndoCollab.com: A Visual Guide to Hemoclips Applications

Conclusion:
The Gastroenterology & Endoscopy field continually evolves with advancements like  Hemoclips, pushing the boundaries and offering new horizons for better patient care. Mastering the use of these clips is not just about enhancing procedural efficiency but also about ensuring safer and improved patient outcomes.

https://www.gastroendopod.com

In this highly informative podcast, we explore the world of Inflammatory Fibroid Polyps or Vanek Tumors of the GI Tract. We discuss everything from their manifestation as submucosal lesions to their immunohistochemical characteristics. Get valuable insights into diagnosis techniques, anatomical locations, and treatment protocols. You'll also learn about the importance of immunohistochemistry in distinguishing between IFPs and other Gastrointestinal stromal tumors (GIST). Join us in our deep dive into this intricate world of gastroenterology.

Read more: https://www.thepracticingendoscopist.com/p/inflammatory-fibroid-polyps-ifp-or

https://www.gastroendopod.com

A phrygian cap gallbladder is a congenital anomaly of the gallbladder with an incidence of 4%. It can simulate a mass in the liver during hepatobiliary imaging and is sometimes mistaken for pathology. A Phrygian cap, however, has no pathological significance and normally causes no symptoms. 

Links:
What is a Phrygian (Cap) Gallbladder?

https://www.gastroendopod.com

Ever wondered about the precision of medical instruments, how they are measured, or who pioneered this system? Join us on a captivating journey as we unearth the intriguing world of medical instrument measurements. We'll highlight the life and contributions of Swiss-French artisan, Joseph Frederick Benoit Chariere, the brain behind the French or Chariere gauge system. Used widely in endoscopy units worldwide, Chariere's precision instrument designs changed medical science forever. We'll discuss everything from scissors to syringes, anesthesia systems, and his innovative gauge system known for its uniform increments.

As we navigate the practical application of the French scale, you'll experience how it aids medical professionals in delivering precise treatments. Our discussion breaks down the complexities of this fascinating system and reveals its role in delivering vital medical equipment like catheters and stents. To bring it all to life, we'll delve into an exciting case study of balloon-assisted endoscopic retrograde colongeopancreatography, illuminating the importance of these measurements in real-world applications. Stay tuned for this engaging exploration into the precision and innovation that is at the heart of medical science.

Links:
- https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0043-119686.pdf
- https://www.thepracticingendoscopist.com/p/where-does-the-measurement-fr-french

https://www.gastroendopod.com