How has our knowledge of COVID-19 and how it affects people with HIV evolved? IDSA board member Max Brito, MD, FIDSA of the University of Illinois at Chicago and HIVMA board member Rachel Bender Ignacio, MD, FIDSA of the University of Washington discuss the latest COVID-19 clinical considerations for people with HIV and the broader impacts of the COVID-19 pandemic on the HIV community and efforts to end the HIV epidemic.