LessWrong (Curated & Popular)

“How Colds Spread” by RobertM


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It seems like a catastrophic civilizational failure that we don't have confident common knowledge of how colds spread. There have been a number of studies conducted over the years, but most of those were testing secondary endpoints, like how long viruses would survive on surfaces, or how likely they were to be transmitted to people's fingers after touching contaminated surfaces, etc.

However, a few of them involved rounding up some brave volunteers, deliberately infecting some of them, and then arranging matters so as to test various routes of transmission to uninfected volunteers.

My conclusions from reviewing these studies are:

  • You can definitely infect yourself if you take a sick person's snot and rub it into your eyeballs or nostrils.  This probably works even if you touched a surface that a sick person touched, rather than by handshake, at least for some surfaces.  There's some evidence that actual human infection is much less likely if the contaminated surface you touched is dry, but for most colds there'll often be quite a lot of virus detectable on even dry contaminated surfaces for most of a day.  I think you can probably infect yourself with fomites, but my guess is that [...]
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Outline:

(01:49) Fomites

(06:58) Aerosols

(16:23) Other Factors

(17:06) Review

(18:33) Conclusion

The original text contained 16 footnotes which were omitted from this narration.

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First published:
November 18th, 2025

Source:
https://www.lesswrong.com/posts/92fkEn4aAjRutqbNF/how-colds-spread

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Narrated by TYPE III AUDIO.

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