Psychedelic Passage

How Do Psychedelics Affect Sleep?


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Sleepiness on psilocybin can stem from both biological and psychological factors, with science pointing to altered brain wave activity and serotonin receptor interactions as key contributors. Research suggests psilocybin induces a paradoxical state of heightened awareness alongside deep relaxation, offering insight into the complex relationship between psychedelics and rest.

Explore the curious and often misunderstood phenomenon of sleepiness during a psilocybin-containing mushroom or other psychedelic experience in today’s article. We’ll break down the different stages in which drowsiness may occur: during the come-up, mid-trip, or afterglow, and offer both scientific and psycho-spiritual perspectives to explain why. 

Drawing from client experiences and current neuroscience, we examine how psilocybin affects brainwaves, information processing, and the serotonin system, potentially triggering a state of paradoxical relaxation and alertness. 

Jimmy also delves into the role of trauma, the body’s need for rest, and the concept of psychedelics as “non-specific amplifiers” of unconscious material. You can find practical advice for those of us struggling with disruptive sleepiness during micro- or macrodosing, alongside cultural reflections on rest, trauma, and integration. 

We close the episode by answering a question from a community member on selecting a psychedelic facilitator, emphasizing the importance of resonance and choice in healing journeys.


No mushroom source? No problem. Download our Free Psilocybin Sourcing Guide.

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About Us:

Psychedelic Passage is the first psychedelic concierge service in the U.S., connecting clients with a vetted network of local, independent facilitators. As an independent body, we ensure no conflict of interest, advocating solely for you. Our rigorous vetting guarantees facilitators who uphold integrity, inspiring trust, confidence, and lasting change. With hundreds of transformational journeys facilitated nationwide, book a Pathfinding Call to get personalized guidance and have all your questions answered.

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