Melvyn Bragg and guests discuss the relevance of psychoanalysis at the end of the 20th century. It’s 100 years since Sigmund Freud, the founder of psychoanalysis, a term which he coined, published The Interpretation of Dreams. Sixty years after his death, Freud’s influence and the influence of that book, has been felt in the 20th century in everything from the arts, history and anthropology, to of course psychology and even science. Dreams have inspired political speeches, songs, and seduction, captivating and fascinating mankind since time immemorial. For Sigmund Freud, they were the key to unlocking the working of the unconscious. But at the end of the 20th century, has psychoanalysis become too fractured and too insistent on privileging the past over the present to go forward into the future? Has it failed to develop and adapt to an age increasingly dominated by science? With Dr Juliet Mitchell, psychoanalyst, Fellow of Jesus College, Cambridge, Department of Political and Social Sciences; Adam Phillips, psychoanalyst and author of The Beast in the Nursery.

Melvyn Bragg and guests discuss ageing. In 1900, 1% of the world’s population were over 65. In the 1990s nearly 8% are. By the year 2020, nearly 1/5th of the world’s population will be over 65 - the figure rises to 25% in the UK. We are now living longer than at any time in our history. How much do economic factors, rather than biological factors, determine what ageing really means and our attitude to it? And what are the ethical, economic and biological implications of living longer?Tom Kirkwood, is an expert on the science of ageing and he brings to bear a close study of how the ageing process is being arrested and speculates on the very great age some of us could and will reach. He has said: “Today’s older people are the vanguard of an extraordinary revolution in longevity that is radically changing the structure of society and altering our perceptions of life and death. The price for this success - and make no mistake it is a success - is that we now face the challenge of ageing.”Alan Walker is an expert in the sociology of ageing and he takes in the whole context, especially the economic dimension. With Professor Alan Walker, social gerontologist, advisor to the UN’s programme on Ageing and has chaired the European Commission’s observatory on Ageing and Older People; Professor Tom Kirkwood, Britain’s first professor of Biological Gerontology, University of Manchester and President of the British Society for Research into Ageing.

Melvyn Bragg and guests debate the state of Modern Culture in the 20th century. Culture used to be a word we mocked, a concept too foreign for the stout empiricists of Britain, a species of foreign flummery. Now it is all around us. We have a ministry for it and a newspaper section boldly called Culture.Is contemporary culture evidence of a moral and aesthetic decline in our civilisation this century? Or does it show a society richer and more diverse than it has ever been?Will Self is one of the best known writers of his generation - celebrated as much for his erudite vocabulary as the shocking subject matter of some of his novels and short stories. Roger Scruton is one of the most celebrated philosophers of our age - known as much for his right -wing politics as for the passion with which he defends the past as a way of looking at the future. His latest book is An Intelligent Person’s Guide to Modern Culture, and he prefaces it by saying: “You don’t have to be familiar with the entire canon of western literature and full range of artistic masterpieces but you should have some familiarity with TS Eliot, Baudelaire, Mozart, Wagner, Monet, Poussin, Tennyson, Schoenberg, George Herbert, Goethe, Nietsche, and Marx.”With Will Self, writer and novelist; Roger Scruton, novelist, philosopher and Former Professor at Birkbeck College, London.

Melvyn Bragg and guests discuss the implications of the developments in genetic engineering. Out of the city of Cambridge in the mid century came DNA and out of Edinburgh at the end of the century came the cloning of Dolly the sheep. These two facts might well do more to change the world literally, and our view of the world, than anything else that has happened at any time. Genetics have become the conversation of our day and with the Human Genome Project lumbering towards completion, its power grows. But are the consequences likely to be destructive and will what we think of as a human being, a personality, or even a person, change uncomfortably and irredeemably? With Grahame Bulfield, geneticist, honorary professor, Edinburgh University and Director of the Roslin Institute, Edinburgh; Bryan Appleyard, features writer for The Sunday Times and author of Brave New Worlds: Genetics and the Human Experience.

Melvyn Bragg and guests discuss one of the most important events of the 20th century - the rise of Feminism and the subsequent empowerment of women. What have been the most important and lasting changes for women in the last 100 years and what is there still left to achieve? Are the biological differences between men and women insuperable? Is the feminist movement therefore set on a course it is inevitably bound to lose? Is the ideology of feminism in other words, working against our natural inclinations?If a man were to say “men are by nature more competitive, ambitious, status-conscious, dedicated, single-minded and persevering than women” then you could be forgiven for calling him anti-diluvian, blinkered and worse. But this is the express view of Dr Helena Cronin from the London School of Economics - a philosopher who has concentrated on Darwinian theory which she claims has never seriously been applied to humans. Joining her is Dr Germaine Greer whose book The Female Eunuch is credited with changing the lives of a generation of women. With Dr Helena Cronin, Co-director of the Centre for the Philosophy of the Natural and Social Sciences, London School of Economics; Dr Germaine Greer, Professor of English and Comparative Studies, Warwick University.

Melvyn Bragg and guests discuss Britain's colonial legacy. The 18th, 19th and early part of the 20th centuries were times of colonial conquest for this country but the abiding image of empire (true or not) is stuck squarely in the 1850’s when Victoria was on the throne and the world map was liberally sprinkled with red. So what does that mean for us as we go into the next millennium - Catherine Hall, Professor of Modern British Social History at University College London, asks us to 're-remember' our colonial past, and suggests that only by acknowledging the guilt it has saddled us with and its legacy of a truly multi-cultural Britain can we face our new life in Europe.Are there different ways of remembering that past, and what effect do these different approaches have on our present? Are we still too close to our imperial past to view it objectively, or is the reverse true - that we are too deeply rooted in our present to learn the lessons of that past? With Catherine Hall, Professor Modern British Social and Cultural History, University College, London; Professor Linda Colley, currently holder of the Leverhulme Research Professorship at the London School of Economics and former Professor of History, Yale University.

Melvyn Bragg and guests marvel at our brains and discuss how at the end of a century of research we still understand so little about how they work.Developments in the understanding of the brain represent one of the major leaps forward in science in the 20th century, and the research is gathering pace and intensity. It’s a subject which captures the imagination, particularly the search for consciousness whatever that might be, and brings together some of the newest technology and the oldest belief systems. What a piece of work is the brain - a grain-of-sand-sized piece contains one hundred thousand neurons, two-million axons and one billion synapses which all talk to each other. How far we have got with our understanding of the brain and what can it tell us about ourselves and the world we live in?With Professor Susan Greenfield, director of the Royal Institution, Professor of Pharmacology, Oxford University and Professor of Physics at Gresham College; Professor Vilayanur Ramachandran, Professor of Neuroscience and Psychology, Director of the Brain Perception Laboratory, University of California in San Diego and Professor at the Salk Institute.

Melvyn Bragg and guests discuss how legitimate it is to call the 20th century the American century. Just how benevolent has America’s impact on the world been? And how durable has American’s initial idealism proved to be? Have ideals of democracy and freedom been forged across the globe as a result of the American influence, or has American oppression made the bigger impact? Has America ignored its own inequalities whilst advocating democratic capitalism elsewhere? Can America still lay claim to the idealism which fired its founders, or has materialism, with its uncomfortable corollary deprivation, lain waste to those early ideals?With Harry Evans, former editor of The Sunday Times, now an American citizen and author of The American Century; John Lloyd, associate editor of The New Statesman and former Times correspondent in Moscow and East European Editor of the Financial Times.

On the fiftieth anniversary of the signing of the Declaration of Human Rights at the United Nations in New York, Melvyn Bragg and guests discuss the current status of that original declaration. Is it possible for any sort of rights to be ‘universal’? What are the implications of the ideas enshrined in that declaration - has the emphasis changed - and if so what are such rights? New thinking in this area has focused on ‘cultural rights’ but do these work alongside human rights, or do they supplant them? Has the advent of globalisation had an impact on human rights, and if so, how? At the end of the 20th century, can we look back to any progress in this area, and, if we look forward, do we see the oncoming train, or the light at the end of the human rights tunnel? With Professor Homi Bhabha, Professor in English Literature and Art, Chicago University and Visiting Professor of the Humanities, University College, London; Profesor John Gray, Professor of European Thought, London School of Economics in January 1998.

Melvyn Bragg and guests discuss the study of history this century. One of the debates raging in the practice of history is between the history of facts versus the imagination - a debate raised again by so-called ‘faction’ - fiction based on documentary facts which is so much in our minds today from films and television. But in fact it is a debate which has been going on throughout the century within history. The 19th century historian Thomas Macaulay wrote that History is under the jurisdiction of two hostile powers; and like other districts similarly situated it is ill-defined, ill-cultivated and ill-regulated. Instead of being equally shared between its two rulers, the Reason and the Imagination, it falls alternately under the sole and absolute dominion of each. It is sometimes fiction and sometimes theory.Why is the study of history important? Is history relevant to us today? Are the truths likely to be yielded from history closer to those disclosed in great novels than the abstract general laws sought by social scientists? And what is the role of imagination in the writing of history? With Simon Schama, Old Dominion Professor of Humanities, Columbia University in New York and currently filming a 16-part series for BBC Television on the history of Britain; Lady Antonia Fraser historian, writer and author of biographies of Mary Queen of Scots, Cromwell and Charles II.