Dr. Laura Baker, PhD, is a professor of gerontology and geriatric medicine at Wake Forest University School of Medicine and the principal investigator of the U.S. POINTER study, a large, Alzheimer’s Association–backed trial inspired by Finland’s landmark FINGER study. Designed to test whether lifestyle can protect brain health in a diverse U.S. population, POINTER enrolled 2,111 adults ages 60 to 79 across five regions. Participants who were not already exercising or eating a Mediterranean-style diet engaged in lifestyle changes across four pillars: physical activity, nutrition, cognitive and social engagement, and tracking health numbers like blood pressure and blood sugar.

In this interview with Being Patient’s Mark Niu, Baker traces how POINTER was designed, what a coach-supported lifestyle program looks like in practice, and why community partners matter. She also previews what’s ahead — from brain imaging to sleep and vascular findings — and offers practical guidance for caregivers and older adults.

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Being Patient is an editorially independent journalism outlet for news and reporting about brain health, cognitive science, and neurodegenerative diseases. In our Live Talk series on Facebook, former Wall Street Journal Editor and founder of Being Patient, Deborah Kan, interviews brain health experts and people living with dementia. 

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