In this February 18, 2025 issue of the JACC, Dr. Valentin Fuster presents groundbreaking studies on topics such as biodegradable polymer stents, myocardial fibroblast activation after heart attacks, and the role of microaxial flow pumps in treating cardiogenic shock. The issue also explores the dangers of ozone exposure on arterial stiffness and highlights expert consensus on arrhythmia monitoring after strokes, offering valuable insights for both cardiology practitioners and researchers.