By JAMA Network
Author interviews that explore the latest clinical reviews.
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Romina Brignardello-Petersen, DDS, PhD, and Gordon Guyatt, MD, of McMaster University talk with JAMA Executive Deputy Editor Robert Golub, MD, about how to interpret clinical practice guidelines and recommendations, the subject of a recent Users’ Guides to the Medical Literature...
Bilateral salpingo-oophorectomy (BSO) causes premature menopause in younger women and is associated with reduced quality of life and cardiovascular, neurologic, and skeletal morbidity and mortality. Ekta Kapoor, MBBS, Associate Professor of Medicine and Assistant Director, Mayo Clinic Center for Women’s...
Recognizing a potentially difficult intubation can help clinicians prepare for complications by getting assistance from colleagues with airway training and by ensuring advanced airway management equipment is available. Michael E. Detsky, MD, MSHP, assistant professor of medicine at the University...
Critically ill patients often require IV fluids for resuscitation but questions remain about the optimal type of IV fluid and best rate of IV fluid bolus infusion. JAMA Associate Editor Kristin Walter, MD, MS, discusses a recent clinical trial that...
Interview with Chien-Wen Tseng, MD, USPSTF member and coauthor of Screening for Prediabetes and Type 2 Diabetes: US Preventive Services Task Force Recommendation Statement. Related Content: Screening for Gestational Diabetes Screening for Prediabetes and Type 2 Diabetes Updated USPSTF...
Interview with Chien-Wen Tseng, MD, USPSTF member and coauthor of Screening for Gestational Diabetes Related Content: USPSTF Review: Screening for Gestational Diabetes USPSTF Recommendation: Screening for Prediabetes and Type 2 Diabetes
Cost-effectiveness analysis defines trade-offs between costs, harms, and benefits of alternative treatments and combines them into a single metric, the incremental cost-effectiveness ratio (ICER), that can inform decisions about which interventions to recommend when limited resources are available. Gillian Sanders-Schmidler,...
Rules for the regulation of medical devices, such as hip prostheses and implantable defibrillators, are complex and differ from those for drugs. Aaron Kesselheim, MD, JD, MPH, and Jonathan Darrow, SJD, LLM, JD, MBA, both faculty members in the Division...
Anabolic drugs activate osteoblasts and are an alternative to bisphosphonates for treating osteoporosis. Kristine Ensrud, MD, MPH, professor of medicine and epidemiology at the University of Minnesota and Minneapolis VA Healthcare System, joins JAMA Associate Editor Carolyn Crandall, MD, MS,...
Several new therapeutic drug classes are now available to manage lipid levels. John Wilkins, MD, MS, and Donald Lloyd-Jones, MD, ScM, of the Department of Preventive Medicine and Division of Cardiology at Northwestern University Feinberg School of Medicine, discuss the...
Alcoholic liver disease is increasing in incidence, especially in younger age groups. Ashwani Singal, MD, MS, professor of medicine at University of South Dakota, reviews the diagnosis, clinical presentation, and management of alcoholic liver disease, from acute alcoholic hepatitis to...
Approximately 1 in 8 women of reproductive age seek treatment for infertility. JAMA Associate Editor Linda Brubaker, MD, joins Sandra Ann Carson, MD, of Yale School of Medicine, to discuss causes and clinical correlates of infertility as well as evaluation...
Transcatheter valve repair has emerged as an important therapeutic option for patients with aortic and mitral valve disease. JAMA Deputy Editor Gregory Curfman, MD, interviews Charles Davidson, MD, clinical chief of Cardiology at Northwestern University, to review the range of...
Chronic pelvic pain is a challenging condition that affects an estimated 26% of the world’s female population. JAMA Associate Editor Linda Brubaker, MD, and Georgine Lamvu, MD, of the University of Central Florida, discuss recommendations from consensus guidelines intended to...
Routine wellness or "checkup" visits are popular with patients and physicians but questions persist about their value, goals, and effective components. JAMA Associate Editor Anne Cappola, MD, ScM, discusses the evidence for and against the practice with Jeffrey Linder, MD,...
Lower extremity peripheral artery disease (PAD) affects approximately 8.5 million people in the US and about 230 million worldwide. JAMA Deputy Editor Greg Curfman, MD, interviews Mary M. McDermott, MD, of Northwestern University Feinberg School of Medicine, to discuss current...
Interview with Aaron B. Caughey, MD, PhD, USPSTF member and coauthor of Behavioral Counseling Interventions for Healthy Weight and Weight Gain in Pregnancy: US Preventive Services Task Force Recommendation Statement Related Content: Counseling and Behavioral Interventions for...
Interview with Michael Barry, MD, USPSTF vice chairperson and author of Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement Related Article(s): Screening for Colorectal Cancer
Headache disorders are one of the most common reasons patients visit emergency rooms and medical offices. Matthew S. Robbins, MD, associate professor of neurology and neurology residency program director at Weill Cornell and New York Presbyterian Hospital, discusses effective migraine...
Headache is one of the most common reasons patients visit emergency rooms and medical offices. Matthew S. Robbins, MD, associate professor of neurology and neurology residency program director at Weill Cornell and New York Presbyterian Hospital, discusses the diagnostic approach...
Chronic stable angina reduces quality of life and only rarely leads to acute coronary syndrome (ACS). Treatment is lifestyle modification to manage atherosclerotic risk factors, with revascularization (eg, PCI or CABG) indicated to reduce symptoms and improve quality of life...
Interview with John B. Wong, MD, USPSTF member and coauthor of USPSTF Recommendation: Screening for Hypertension in Adults Related Content: Screening for Hypertension in Adults The 2021 USPSTF Recommendation on Blood Pressure Screening USPSTF Recommendation: Screening...
Dual antiplatelet therapy, typically aspirin and an oral P2Y12 receptor inhibitor (clopidogrel, prasugrel, ticagrelor, cangrelor), reduces adverse events after acute coronary syndrome (ACS) but choice of agent and optimal duration may be patient-specific. Umair Khalid, MD, a cardiologist at the...
Interest in space travel has increased since SpaceX’s first commercial launch to the International Space Station (ISS) in May 2020 and with efforts to send humans to Mars. Serena Auñón-Chancellor, MD, MPH, a physician-astronaut who completed a 6-month mission to...
Interest in space travel has increased since SpaceX’s first commercial launch to the International Space Station in May 2020 and with efforts to send humans to Mars. Jim Bagian, MD, a physician-astronaut who logged 337 hours in space between 1989...
Shyam Prabhakaran, MD, chairman of neurology at the University of Chicago, discusses the diagnosis and evaluation of patients who present with transient ischemic attack (TIA) and stroke. Related Article: Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic...
Semaglutide has recently been shown to induce clinically significant weight loss in patients with obesity that is sustained for as long as the drug is given. Tom Wadden, PhD, from the University of Pennsylvania, discusses results from the series of...
Performing repeated statistical comparisons on data can result in false-positive findings. Jing Cao, PhD, associate professor of statistics at Southern Methodist University, explains problems that can arise from multiple testing procedures and how to avoid making false conclusions. Related Article:...
Irritable bowel syndrome (IBS) is a clinical syndrome of vague abdominal pain and cramping associated with diarrhea or constipation. IBS is a diagnosis of exclusion, and a variety of treatments can improve its symptoms. Michael Camilleri, MD, professor of medicine...
The Pfizer-BioNTech and Moderna COVID-19 mRNA vaccines are the first of many being tested for widespread use. Buddy Creech, MD, MPH, director of the Vanderbilt Vaccine Research Program, reviews these and other vaccines likely to become available, including products that...
Advance directives (ADs) allow patients to express their medical treatment preferences. Patients with ADs are more likely to receive medical care concordant with their wishes and are less likely to die in the hospital than patients without them, but use...
The CDC coordinated a massive effort to immunize nearly all nursing home and long-term care facility residents in the US against COVID-19 infection in the month after vaccine approval. Ruth Link-Gelles, PhD, MPH, CDC staff epidemiologist and Lieutenant Commander of...
Highly effective B-cell therapies like rituximab and ofatumumab have changed the outlook for patients with multiple sclerosis (MS). Alexander Rae-Grant, MD, emeritus professor of neurology at the Cleveland Clinic Lerner College of Medicine, discusses recent advances in the diagnosis and...
This is Dr Howard Bauchner, Editor in Chief of JAMA and the JAMA Network. The podcast on structural racism based on the discussion between Dr Ed Livingston and Dr Mitch Katz has been withdrawn. Comments made in the podcast were...
Natural experiments comparing coronavirus spread on ships and in hair salons with vs without face masks point to the importance of wearing masks for curbing SARS-CoV-2 spread. John T. Brooks, MD, chief medical officer of the CDC’s COVID-19 response team,...
Philip Cohen, MD, associate clinical professor of internal medicine at UCLA, a primary care internist who also specializes in sports medicine, discusses the primary care management of osteoarthritis. Related Articles: Drugs for Osteoarthritis Diagnosis and Treatment of...
Immune checkpoint inhibitors have been a major breakthrough in cancer treatment but can have many serious adverse effects. Pankti Reid, MD, MPH, assistant professor of medicine in rheumatology at the University of Chicago, discusses the pathogenesis, diagnosis, and treatment of...
Howard Reber, MD, emeritus professor of surgery at UCLA, discusses how to treat acute pancreatitis. Related Article(s): Acute Pancreatitis
Howard Reber, MD, emeritus professor of surgery at UCLA, discusses how to diagnose acute pancreatitis. Related Article(s): Acute Pancreatitis
Ethnic and racial minorities have been particularly hard hit with COVID-19 in some communities. Mitchell Katz, MD, president and chief executive officer of New York City Health + Hospitals, and former Los Angeles County health agency director, discusses this problem...
Tobacco use is the leading cause of preventable disease and death in the world, but most attempts to quit are unsuccessful. Atul Jain, MD, assistant professor of medicine at Mayo College of Medicine, discusses new guidelines from the American Thoracic...
Mitchell Katz, MD, president and chief executive officer of New York City Health + Hospitals, and former Los Angeles County health agency director, discusses causes, similarities, and differences between the spike of COVID-19 cases, hospitalizations, and deaths in the 2...
Glaucoma is the most common cause of irreversible blindness in the world. Joshua Stein, MD, MS, associate professor of ophthalmology at the University of Michigan, reviews the diagnosis and treatment of glaucoma. Related Article: Glaucoma in Adults—Screening, Diagnosis, and...
A new trial reports that a third of emergency department patients presenting with appendicitis admitted for oral antibiotic treatment had outcomes no different from those admitted for intravenous antibiotic treatment. Paulina Salminen, MD, PhD, professor of surgery at the University...
Gregory Armstrong, MD, director of the Advanced Molecular Detection Program for the CDC, explains what is currently known about the new mutations of SARS-CoV-2. Related Article(s): Genetic Variants of SARS-CoV-2—What Do They Mean? Next-Generation Sequencing of Infectious Pathogens...
Next-generation sequencing is a catchall term for new, high-throughput technologies that allow rapid sequencing of a full genome. It can be used to sequence a patient’s DNA in diagnosing a genetic disorder or characterizing a cancer, but it can also...
Tom Shimabukuro, MD, MPH, MBA, and Sara Mbaeyi, MD, MPH, from the CDC discuss rare allergic complications in patients who received the first dose of the Pfizer-BioNTech vaccine between December 14-23, 2020.
Patent foramen ovale (PFO) is an often overlooked cause of acute ischemic stroke. JAMA Associate Editor Jeffrey Saver, MD, professor of neurology at UCLA, discusses new recommendations from a 2020 AAN Practice Advisory about use of mechanical PFO closure and...
New therapies have greatly improved outcomes for patients with Crohn disease. Peter Higgins, MD, from the University of Michigan, discusses advances in management and treatment protocols. Related Article: Management of Crohn Disease
Adam Lauring, MD, PhD, from the University of Michigan Division of Infectious Diseases, an expert on the evolutionary biology of RNA viruses, explains the new genetic variants recently found in SARS-CoV-2 and their importance. Related Article(s): Genetic Variants of...