American Journal of Psychiatry Audio

July 2022: Digital Intervention for Cognitive Deficits in Major Depression


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Dr. Richard S.E. Keefe (Duke University Medical Center, Durham, North Carolina) discusses an article looking at an intervention for major depressive disorder that takes the form of a videogame. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the July issue’s theme.

  • Keefe interview: [01:00]
  • What were your results? [03:13]
  • What do videogames offer as a depression intervention? [03:43]
  • Differences between the intervention and the control intervention [05:05]
  • What was the impact of the interventions? [06:51]
  • What were the limitations of the design and what might change going forward? [08:10]
  • Does the patient’s perception of the effectiveness of the intervention matter? [09:20]
  • How the intervention differs from a similar intervention aimed at children [10:19]
  • Is there an advantage to “hiding” the intervention as a videogame? [11:33]
  • Designing a game and an intervention that work simultaneously [13:27]
  • What next for your research? [15:05]
  • Kalin interview [16:11]
  • Keefe et al. [16:22]
  • Tabuteau et al. [18:15]
  • Ge et al. [20:54]
  • Pan et al. [22:01]
  • Tamm et al. [23:47]
  • Pizzagalli [25:30]
  • Grogans et al. [26:02]

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