Dr. Richard S.E. Keefe (Duke University Medical Center, Durham, North Carolina) discusses an article looking at an intervention for major depressive disorder that takes the form of a videogame. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin discusses the July issue's theme.

• Keefe interview: [01:00]
• What were your results? [03:13]
• What do videogames offer as a depression intervention? [03:43]
• Differences between the intervention and the control intervention [05:05]
• What was the impact of the interventions? [06:51]
• What were the limitations of the design and what might change going forward? [08:10]
• Does the patient's perception of the effectiveness of the intervention matter? [09:20]
• How the intervention differs from a similar intervention aimed at children [10:19]
• Is there an advantage to "hiding" the intervention as a videogame? [11:33]
• Designing a game and an intervention that work simultaneously [13:27]
• What next for your research? [15:05]
• Kalin interview [16:11]
• Keefe et al. [16:22]
• Tabuteau et al. [18:15]
• Ge et al. [20:54]
• Pan et al. [22:01]
• Tamm et al. [23:47]
• Pizzagalli [25:30]
• Grogans et al. [26:02]

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