Cornel N. Stanciu, M.D., C.P.E., M.R.O. is an Assistant Professor of Psychiatry at Dartmouth’s Geisel School of Medicine and the Director of Addiction Services at New Hampshire Hospital. As an Addiction Psychiatrist, Dr. Stanciu is involved in clinical care, research, and policy concerning services and treatments for people with addictive disorders.  Throughout his career, Dr. Stanciu has played an active role in academia having published over 40 papers on themes related to addictive disorders, particularly new psychoactive drugs, such as Kratom, and has received multiple awards for excellence in research and clinical care.

Articles Discussed in the Interview:

1) Pharmacotherapy for Management of Kratom Use Disorder': A Systematic Literature Review With Survey of Experts 

https://www.researchgate.net/profile/Saeed-Ahmed-34/publication/349536203_Pharmacotherapy_for_Management_Kratom_use_disorder/links/6036b0c2a6fdcc37a84d9e02/Pharmacotherapy-for-Management-Kratom-use-disorder.pdf 

2) What Is the Kratom Overdose Risk? A Systematic Literature Review

What Is the Kratom Overdose Risk? A Systematic Literature Review | Current Addiction Reports (springer.com)

3) Prevalence, Characteristics, and Reasons for Kratom Use among Psychiatrically Ill Inpatients Who Use Substances

https://www.tandfonline.com/doi/abs/10.1080/15504263.2023.2289456

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A voice mail from a listener. Cody has a history of poly-substance addiction. With a military background, he excels at staying fit and on track. But he found himself struggling with kratom after finding it a couple years ago, and it reminded him of his days on stronger opioids. His persistence pays off and he is able to interrupt and discontinue his kratom use despite it being so ubiquitously available.

RESOURCE OF THE WEEK

New Sunday 8pm EST Meeting (general quitting kratom / FF friendly)

KRATOM IN THE HEADLINES

NJ lawmakers advance bill to ban herbal product ‘kratom’ after death of Monmouth County man (news12.com)

https://newjersey.news12.com/nj-lawmakers-advance-bill-to-ban-herbal-product-kratom-after-death-of-ocean-county-man

CJ’s Law, a bill that would criminalize kratom in New Jersey, awaits vote – Star News Group

https://starnewsgroup.com/2024/07/02/cjs-law-a-bill-that-would-criminalize-kratom-in-new-jersey-awaits-vote-after-passing-out-of-assembly-committee/ 

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First of a series of special episodes coming out this summer on Wednesdays with guests talking about kratom related topics beyond the wonderful quitting stories usually featured on Sundays.

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Hiding your kratom addiction. From Courtney's email to the show: "...after {getting up to} 44gpd in capsules, I went cold turkey. I discovered kratom after my mom had passed in February last year - I used to have a pill habit so when my mom left us with oxys, I ended up taking all of them, only to run out and behold - kratom had been discovered. I want to somehow advocate for those who want to quit this stuff because I actually can attest to all of the withdrawals and how addictive they are."

Trigger Warning: discussion of suicidal thinking.

RESOURCE OF THE WEEK

New kratom mentoring program for those early in their recovery. Attend any of the non-KA meetings for additional information.

KRATOM IN THE HEADLINES

Exotic Plants, Deadly Consequences: The Feel Free Story (youtube.com)

https://www.youtube.com/watch?v=SOs1U5IOMWI

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Why do kratom users carry around spoons and a knife? Jack got to spending up to $600 a week on kratom and becoming 40 pounds underweight in part because of often throwing up after eating meals as a result of kratom-related nausea. After a short-term detox, Jack is about to reach being a year kratom free by helping to lead the Saturday morning quitting meeting, naltrexone, and therapy.

RESOURCE OF THE WEEK

Quitting Kratom Meeting and WhatsApp

KRATOM IN THE HEADLINES

Why doctors and advocates disagree on kratom, the herb poised for legalization in RI (msn.com)

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Responding to recent podcast feedback. Hilary at one time had two years off kratom, but after a step backwards returning to capsule use, is now reinvesting in her recovery by being active in the quitting community, service work, healthy eating, going to the gym, support from loved ones and pursuing goals for her future. 

RESOURCE OF THE WEEK ARTICLES

Annuar, Nur Aisyah Khairul, Ummi Kalthum Azlan, Ahmed Mediani, Xiaohui Tong, Rongchun Han, Ebtesam Al-Olayan, Syarul Nataqain Baharum, et al. 2024. “An Insight Review on the Neuropharmacological Effects, Mechanisms of Action, Pharmacokinetics and Toxicity of Mitragynine.” Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie 171 (February): 116134. https://doi.org/10.1016/j.biopha.2024.116134.

Huestis, Marilyn A., Martin A. Brett, John Bothmer, and Ramsey Atallah. 2024. “Human Mitragynine and 7-Hydroxymitragynine Pharmacokinetics after Single and Multiple Daily Doses of Oral Encapsulated Dried Kratom Leaf Powder.” Molecules 29 (5): 984. https://doi.org/10.3390/molecules29050984.

Mongar, Pooja, Amit Jaisi, Thammasin Inkviya, Juraithip Wungsintaweekul, and Kamonthip Wiwattanawongsa. 2024. “Effects of Itraconazole on Pharmacokinetics of Mitragynine and 7-Hydroxymitragynine in Healthy Volunteers.” ACS Pharmacology & Translational Science, February. https://doi.org/10.1021/acsptsci.3c00335.

Tanna, R.S., James T. Nguyen, Deena L. Hadi, Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, and Mary F. Paine. 2023. “Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom.” Clinical Pharmacology and Therapeutics 113 (6): 1315–25. https://doi.org/10.1002/cpt.2891.

KRATOM IN THE HEADLINES

A Deadly Get-Together With a Plant-Based Preparation of Kratom (medscape.co.uk)

https://www.medscape.co.uk/viewarticle/deadly-get-together-plant-based-preparation-kratom-2024a10004tp

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The challenge of celebrating being "kratom-free" online. James became addicted to a new 7OHM product and warns listeners to stay away from them.  WARNING: James is not committing to quit kratom completely but rather to stay away from 70hm isolates. 

RESOURCE OF THE WEEK 

June 15, 2024 - 9am to 9pm EST: Kratom Meeting Marathon 

REMINDER - New Friday Noon Meeting 12pm EST

Meeting Link for both (no passcode): https://meet.google.com/nje-jmni-hhb

KRATOM IN THE HEADLINES

Is kratom tea just as addictive as opioids? – WFTV

https://www.wftv.com/news/local/9-investigates-is-kratom-tea-just-addictive-opioids/MZ7YY5LTWNBD7KNWD43C2U75UI/ 

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Having fun kratom-free. Sober from both alcohol and drugs for over a decade, it took Matt about 10 months to hit a bottom with kratom. Through the 12 steps and MAT (including the Sublocade shot), he's now giving back to the community by hosting online kratom support meetings.

RESOURCE OF THE WEEK 

June 15, 2024 - 9am to 9pm EST: Kratom Meeting Marathon 

REMINDER - New Friday Noon Meeting 12pm EST

Meeting Link for both (no passcode): https://meet.google.com/nje-jmni-hhb

KRATOM IN THE HEADLINES

Is kratom tea just as addictive as opioids? – WFTV

https://www.wftv.com/news/local/9-investigates-is-kratom-tea-just-addictive-opioids/MZ7YY5LTWNBD7KNWD43C2U75UI/ 

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Escalatory risks of kratom use. Ryan quit drinking six years ago, but when his beloved dad died, he became addicted to the popular kratom/kava drinks, spending upward of $30,000 on the habit. He ended up abusing opiates for the first time in his life and relapsed on alcohol before he was finally able to quit kratom and pursue complete abstinence. Article discussed:

Kratom use disorder as a gateway to an opioid use disorder - PMC (nih.gov)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661217/ 

RESOURCE OF THE WEEK 

New Friday Noon Meeting 12pm EASTERN: www.kratommeetings.com

KRATOM IN THE HEADLINES

'We've got to keep Georgians safe': New state law cracks down on Kratom sales (msn.com)

https://www.msn.com/en-us/health/other/weve-got-to-keep-georgians-safe-new-state-law-cracks-down-on-kratom-sales/ar-BB1mplJd?ocid=BingNewsSerp 

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Extract / tonic user addiction checklist. New meeting on Friday nights 8pm EST. Jasmine fell into the kratom pickle after quitting booze, found herself unexpectedly hooked on the popular kratom-kava drinks, leading her to getting into significant debt. Finally admitting to herself she was in trouble; a major turning point was telling a loved one in real life she was really struggling with an addiction to this product.

Jasmine's podcast: https://open.spotify.com/show/5fenNr0vnlfSeJyqB6vXUz?si=ba0fa340c41d4619 

RESOURCE OF THE WEEK 

New Friday Night Meeting 8pm: www.kratommeetings.com

Your Brain on Laughter: https://youtu.be/6752cPhrJQ8?si=luH08bDcfNjL6ufk 

Kratom: What is it & what are the risks? – WFTV

https://www.wftv.com/news/local/kratom-what-is-it-what-are-risks/CZHDTF74QVAKHDTLAB5V7QTM6U/ 

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