Concussion is often minimised as a “head knock,” yet it represents a complex traumatic brain injury with far-reaching systemic consequences. In this episode, we welcome Louise Cork to unpack the physiological cascade that unfolds following impact — from axonal shearing and ionic shifts to glutamate excitotoxicity, blood-brain barrier disruption, neuroinflammation, and gut permeability. We explore how this acute response can evolve into persistent post-concussion syndrome (PCS), and why some patients remain symptomatic months, or even years, after the initial injury.

Through a functional naturopathic lens, this conversation provides practical guidance on assessment, red flags, collaborative care, and therapeutic layering, while discussing the critical role of the gut-brain axis, immune activation, metabolic dysfunction, glial priming, autonomic dysregulation, and mitochondrial compromise. With the right support — nutrients, targeted herbal medicine, and realistic lifestyle rehabilitation, post-concussion outcomes are not fixed, and meaningful recovery is possible.