Sam Harris speaks with Kathryn Paige Harden about public controversy over group differences in traits like intelligence and ongoing research in behavioral genetics. They discuss Harden’s criticism of the Making Sense episode featuring Charles Murray, the mingling of scientific thinking with politics and social activism, cancel culture, environmental and genetic contributions to individual and group differences, intellectual honesty, and other topics.

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Sam Harris speaks with Robert Plomin about the role that DNA plays in determining who we are. They discuss the birth of behavioral genetics, the taboo around studying the influence of genes on human psychology, controversies surrounding the topic of group differences, the first law of behavior genetics, heritability, nature and nurture, the mystery of non-shared environment, the way genes help determine a person's environment, epigenetics, the genetics of complex traits, dimensions vs disorders, the prospect of a GATTACA-like dystopia and genetic castes, heritability and equality of opportunity, the implications of genetics for parenting and education, DNA as a fortune-telling device, and other topics.

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Sam Harris speaks with William J. Perry and Lisa Perry about the ever-present threat of nuclear war. They discuss the history of nuclear weapons, the bombing of Hiroshima and Nagasaki, the Cuban Missile Crisis, the present threat of accidental nuclear war, nuclear terrorism, unilateral disarmament, the psychology of deterrence, tactical nuclear weapons, cybersecurity, details of command and control, nuclear proliferation, the steps we could take toward safety, strategic missile defense, nuclear winter, and other topics.

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Sam Harris speaks with Scott Barry Kaufman about human well-being. They discuss intelligence and creativity, wisdom and transcendence, the history of humanistic psychology, Maslow's hierarchy of needs, the connection between well-being and ethics, self-esteem, psychedelics and meditation, peak and plateau experiences, mortality salience, the pre-trans fallacy, fear of uncertainty, work and meaning, intrinsic vs. extrinsic rewards, pathological altruism, intimacy vs. belonging, two aspects of self-transcendence, and other topics.

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Sam Harris speaks with Toby Ord about preserving the long term future of humanity. They discuss moral biases with respect to distance in space and time, the psychology of effective altruism, feeling good vs doing good, possible blindspots in consequentialism, natural vs human-caused risk, asteroid impacts, nuclear war, pandemics, the potentially cosmic significance of human survival, the difference between bad things and the absence of good things, population ethics, Derek Parfit, the asymmetry between happiness and suffering, climate change, and other topics.

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Sam discusses the recent social protests and civil unrest, in light of what we know about racism and police violence in America.

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Sam Harris speaks with David Frum about the shifting political landscape. They discuss the secularization of politics, distrust of the media and other institutions, voter suppression, the 2020 elections, what happens if Trump gets a second term, the role of money in politics, conspiracy theories around Covid-19, the Michael Flynn controversy, the prospect that Trump will refuse to leave office, and other topics.

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Sam Harris speaks with Daniel Markovits about the problems with meritocracy. They discuss the nature of inequality in the United States, the disappearance of the leisure class, the difference between labor and capital as sources of inequality, the way the education system amplifies inequality, the shrinking middle class, deaths of despair, differing social norms among the elite and the working class, the ethics of taxation, scales of philanthropy, universal basic income, the need for a wealth tax, the relationship between meritocracy and political polarization, the illusion of earned advantages, and other topics.

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Sam Harris speaks with Jonathan Haidt about the maintenance of a healthy society. They discuss the problem of orthodoxy, the history of political polarization in the US, the breakdown of public conversation, remaining uncertainty about Covid-19, motivated reasoning, the 2020 election, the future prospects for Gen Z, the effect of social media on the mental health of girls, Jonathan's experience with psychedelics, positive psychology, loss of self, the experience of awe, and other topics.

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Sam Harris speaks with Caitlin Flanagan about her cancer recurrence and the response to her recent article in The Atlantic discussing it. They discuss the dynamics of apologies and forgiveness, the #MeToo movement and the allegations against Biden, modern feminism, and other topics.

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