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Have your muscle gains stalled? Do you struggle to build muscle as fast as others despite your best efforts in the gym?
Philip (@witsandweights) connects with anatomy expert Justin Cottle to dive deep into the cellular world of muscle hypertrophy. You'll learn why some people build muscle faster, what happens inside your muscles as they adapt to strength training, and how understanding these processes can unlock your muscle-building potential. If you want to go beyond the surface level and truly understand how to build muscle efficiently, this is for you.
Justin Cottle, a former lab director at the Institute of Human Anatomy, returns to the show to break down the science of muscle fibers, the role of protein synthesis, and how our genetics influence muscle growth.
🔔 Make sure to hit “follow” to be notified of more episodes like these!
Today, you’ll learn all about:
2:02 Cellular differences between hypertrophied and untrained muscle
3:37 Breaking down muscle fibers and tissue layers
7:15 Fast-twitch vs. slow-twitch muscle fibers
10:03 The role of protein and amino acids in muscle growth
15:30 The connection between carbs and glycogen storage
20:22 The three types of muscle tissues
24:18 Eccentric vs. concentric contractions and training
28:48 Training variation and breaking through plateaus
32:44 Genetic variability in muscle fiber composition
36:43 Mechanisms beyond individual fiber growth (e.g., hyperplasia)
39:09 The importance of rest and recovery for hypertrophy
45:30 Role of muscle damage in hypertrophy
49:34 Practical strategies and training methods for lifters
52:21 Advancements in muscle growth science
55:50 Where to find Justin
56:24 Outro
Episode resources:
Related episode:
đź’Ş Join Eat More Lift Heavy - a 26-week evidence-based strength training and fat loss program for lifters over 40 to build muscle, lose fat, and maintain your weight loss and physique (even in perimenopause and menopause)
📱 Get Fitness Lab - AI-powered coaching app for evidence-based fitness and nutrition over 40. Real-time, personalized guidance that evolves with your data and lifestyle to help you build muscle, lose fat, and body recomp
👥 Join our Facebook community - For adults over 40 who want to build muscle with strength training and lose fat with evidence-based nutrition. Support for lifting weights, hypertrophy, fat loss, and hormones.
👋 Ask a question or find Philip Pape (evidence-based nutrition coach) on Instagram & thanks for making us one of the best fat loss and nutrition podcasts for adults over 40! 🙏
By Philip Pape, Evidence-Based Nutrition Coach, Strength Training & Fat Loss Expert4.9
225225 ratings
Have your muscle gains stalled? Do you struggle to build muscle as fast as others despite your best efforts in the gym?
Philip (@witsandweights) connects with anatomy expert Justin Cottle to dive deep into the cellular world of muscle hypertrophy. You'll learn why some people build muscle faster, what happens inside your muscles as they adapt to strength training, and how understanding these processes can unlock your muscle-building potential. If you want to go beyond the surface level and truly understand how to build muscle efficiently, this is for you.
Justin Cottle, a former lab director at the Institute of Human Anatomy, returns to the show to break down the science of muscle fibers, the role of protein synthesis, and how our genetics influence muscle growth.
🔔 Make sure to hit “follow” to be notified of more episodes like these!
Today, you’ll learn all about:
2:02 Cellular differences between hypertrophied and untrained muscle
3:37 Breaking down muscle fibers and tissue layers
7:15 Fast-twitch vs. slow-twitch muscle fibers
10:03 The role of protein and amino acids in muscle growth
15:30 The connection between carbs and glycogen storage
20:22 The three types of muscle tissues
24:18 Eccentric vs. concentric contractions and training
28:48 Training variation and breaking through plateaus
32:44 Genetic variability in muscle fiber composition
36:43 Mechanisms beyond individual fiber growth (e.g., hyperplasia)
39:09 The importance of rest and recovery for hypertrophy
45:30 Role of muscle damage in hypertrophy
49:34 Practical strategies and training methods for lifters
52:21 Advancements in muscle growth science
55:50 Where to find Justin
56:24 Outro
Episode resources:
Related episode:
đź’Ş Join Eat More Lift Heavy - a 26-week evidence-based strength training and fat loss program for lifters over 40 to build muscle, lose fat, and maintain your weight loss and physique (even in perimenopause and menopause)
📱 Get Fitness Lab - AI-powered coaching app for evidence-based fitness and nutrition over 40. Real-time, personalized guidance that evolves with your data and lifestyle to help you build muscle, lose fat, and body recomp
👥 Join our Facebook community - For adults over 40 who want to build muscle with strength training and lose fat with evidence-based nutrition. Support for lifting weights, hypertrophy, fat loss, and hormones.
👋 Ask a question or find Philip Pape (evidence-based nutrition coach) on Instagram & thanks for making us one of the best fat loss and nutrition podcasts for adults over 40! 🙏

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