Neurology® Podcast

1) Dichlorphenamide in periodic paralysis 2) What's Trending: Editorial on the Zika Virus and what the neurologist wants to know3) Topic of the month: Migraine awareness seriesThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Valeria Sansone about her paper on dichlorphenamide in periodic paralysis. Dr. Ted Burns is interviewing Dr. Gretchen Birbeck for our "What's Trending" feature of the week about her editorial on the Zika Virus and what the neurologist wants to know. Dr. Tesha Monteith interviews Dr. Peter Goadsby about the topic of science behind lifestyle factors: Our basic instincts and the migraine brain. DISCLOSURES: Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Birbeck serves as Section Editor and Curator for Without Borders mini-site Neurology®; receives research support from the NIH and Dana Foundation Neuroimaging Grant.Dr. Monteith serves as an editorial advisory board member for Neurology Now and receives research support from the NIH.Dr. Goadsby serves as an editorial board member for Journal Watch Neurology; receives royalties from the publication of Mechanism and Management of Headache. (7th ed.); was a consultant for Alder Bio, Allergan, Inc., Amgen, ATI, Boehringer Ingelheim, BMS, Boston Scientific, Colucid, Coherex, DrReddy, Eli Lilly and Company, Gammacore, GlaxoSmithKline, Impax, J&J Linde Gases, Lundbeck Inc., MAP Pharmaceuticals, Medtronic, Inc., MSD, Neuralieve, Nevrocorp, Pfizer Inc, Zogenix; receives research support from Amgen and Allergan, Inc.; has worked with legal firms handling patent matters.

1) Mid-life exercise blood pressure, heart rate and fitness relate to brain volume two decades later2) What's Trending: Antibiotic-associated encephalopathy 3) Topic of the month: Migraine awareness seriesThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interviews Dr. Nicole Spartano about her paper on the mid-life exercise blood pressure, heart rate and fitness and how it relates to brain volume two decades later. Dr. Ted Burns is interviewing Dr. Shamik Bhattacharyya for our "What's Trending" feature of the week about his paper on antibiotic-associated encephalopathy. Dr. Tesha Monteith interviews Dr. Aarno Palotie about the topic of migraine genetics: What have we learned. DISCLOSURES: Dr. Jeff Burns serves on the editorial board for Journal of Alzheimer's Disease; receives royalties for the publications of Early diagnosis and treatment of mild cognitive impairment and Dementia: An atlas of investigation and diagnosis; is a consultant for PRA International and receives research support from the NIH, Alzheimer's Drug Discovery Foundation, Elan, Janssen Pharmaceuticals Inc., Wyeth, Pfizer Inc, Novartis Pharmaceuticals Ltd, Danone, Avid Radiopharmaceuticals, Merck Serono and for clinical trials.Dr. Spartano receives research support from the NIH.Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Monteith serves as an editorial advisory board member for Neurology Now and receives research support from the NIH.Dr. Palotie serves as a member of the Pfizer Genetics Scientific Advisory Panel; receives research support from Finnish Academy, European Union NIH, NINDS, Juselius Foundation and Finnish Foundation for Cardiovascular Research.

1) Neurology® Clinical Practice article titled: How do you treat anti-NMDA receptor encephalitis?2) e-Pearl topic: Primary lateral sclerosis3) Topic of the month: Pediatric multiple sclerosis This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Lara Marcuse interviews Dr. Luca Bartolini about his Neurology: Clinical Practice paper on how you treat anti-NMDA receptor encephalitis. Dr. Steve O'Donnell is reading our e-Pearl of the week about primary lateral sclerosis. In the next part of the podcast Dr. Nick Brenton interviews Dr. Leigh Charvet about the topic of cognitive, emotional and behavioral outcomes in pediatric multiple sclerosis. DISCLOSURES: Dr. Bartolini serves as Section Editor for Neurology Clinical Practice.Dr. O'Donnell serves on the editorial team for the Neurology Resident and Fellow Section.Dr. Charvet has received research support from Novartis.NO CME WILL BE OFFERED THIS WEEK.

1) Statin pretreatment is associated with better outcomes in large-artery atherosclerotic stroke2) e-Pearl topic: Fatal familial insomnia3) Topic of the month: Pediatric multiple sclerosis This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Andy Southerland interviews Dr. Georgios Tsivgoulis about his paper on how statin pretreatment is associated with better outcome in large-artery atherosclerotic stroke. Dr. Steve O'Donnell is reading our e-Pearl of the week about fatal familial insomnia. In the next part of the podcast Dr. Ruth Ann Marrie interviews Dr. Emmanuelle Waubant about the topic of vitamin D in pediatric multiple sclerosis. DISCLOSURES: Dr. Southerland serves as Podcast Deputy Editor for Neurology; serves as Clinical Research Advisor for Totier Technologies, Inc.Dr. Tsivgoulis serves as Associate Editor for Neurosonology; serves as an editorial board member of Journal of Neuroimaging; and receives research support from the European Regional Development Fund.Dr. O'Donnell serves on the editorial team for the Neurology Resident and Fellow Section.Dr. Marrie serves as an editorial board member of Neurology and Multiple Sclerosis Journal; receives research support for clinical trials from Sanofi-Aventis, from the Canadian Institutes of Health Research, Research Manitoba, from Multiple Sclerosis Society of Canada and the National Multiple Sclerosis Society, from Multiple Sclerosis Scientific Foundation and from Consortium of Multiple Sclerosis Centers; received research support from the Public Health Agency of Canada.Dr. Waubant serves on the scientific advisory board for Novartis; serves as an editorial board member of Annals of Clinical and Translational Neurology; is an ad hoc consultant for Roche and MedDay; received funding for travel for one educational physician lecture from Genentech, Inc.; receives royalties from the publication of the book Demyelinating disorders of the central nervous system in childhood; receives research support for trials of ocrelizumab in PPMS (Roche), and fingolimod in pediatric MS (Novartis); receives research support from the National Multiple Sclerosis Society, the Race to Erase MS and NIH.

1) Metabotropic glutamate receptor type 1 autoimmunity: Clinical features and treatment outcomes2) What's Trending: Editorial on if stress could cause a stroke3) Topic of the month: Pediatric multiple sclerosis This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Kathryn Nevel interviews Dr. Andrew McKeon about his paper on clinical features and treatment outcomes of metabotropic glutamate receptor type 1 autoimmunity. Dr. Ted Burns is interviewing Dr. Jennifer Majersik for our "What's Trending" feature of the week about her editorial on if stress could cause a stroke. In the next part of the podcast Dr. Ruth Ann Marrie interviews Dr. Ann Yeh about the topic of exercise in pediatric multiple sclerosis. DISCLOSURES: Dr. McKeon receives research support from Medimmune, Inc.Dr. Ted Burns serves as Podcast Editor for Neurology; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Majersik serves as an editorial board member of Neurology; and receives research support from the NIH.Dr. Marrie serves as an editorial board member of Neurology and Multiple Sclerosis Journal; receives research support for clinical trials from Sanofi-Aventis, from the Canadian Institutes of Health Research, Research Manitoba, from Multiple Sclerosis Society of Canada and the National Multiple Sclerosis Society, from Multiple Sclerosis Scientific Foundation and from Consortium of Multiple Sclerosis Centers; received research support from the Public Health Agency of Canada.Dr. Yeh perform multiple sclerosis relapse adjudication for ACI services on a fee-for-service basis; serves as an editorial board member of Neurology; receives research support from the Canadian Institutes of Health Research, Patient-Centered Outcomes Research Institute, MS Monitoring system pilot funding, National MS Society, MS Society, Dairy Farmers of Ontario, SickKids Innovation Fund, MS Research Foundation (Canada), and Rare Diseases Foundation.

1) Transient ischemic attack service provision: A review of available service models2) What's Trending: Mediterranean diet and brain structure in a multiethnic elderly cohort3) Topic of the month: Pediatric multiple sclerosis This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Bryan Eckerle interviews Dr. Anna Ranta about her paper on transient ischemic attacks as predictors of high risk for subsequent strokes. Dr. Ted Burns is interviewing Dr. Yian Gu for our "What's Trending" feature of the week about his paper on the Mediterranean diet and brain structure in a multiethnic elderly cohort. In the next part of the podcast Dr. Nick Brenton interviews Dr. Daniela Pohl about the topic of disease-modifying therapy management in pediatric multiple sclerosis. DISCLOSURES: Dr. Ranta receives research support from the New Zealand Health Research Council.Dr. Ted Burns serves as Podcast Editor for Neurology; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Pohl received funding for travel from Teva Pharmaceutical Industries Ltd., Bayer Schering Pharma, ENS, Merck Serono, Consortium of Multiple Sclerosis Center, LACTRIMS and National Multiple Sclerosis Society; received speaker honoraria from Teva Pharmaceutical Industries Ltd., Bayer Schering Pharma, Merck Serono and Consortium of Multiple Sclerosis Center; serves on the scientific advisory board for Biogen Idec and Merck Serono.

1) Neurology® Neuroimmunology & Neuroinflammation: Therapy with natalizumab is associated with high JCV sero-conversion and rising JCV index values 2) What's Trending: Interviews with Sandi Moriarity and Andy Lucas about their positions and responsibilities with the Neurology podcasts3) Topic of the month: Pediatric multiple sclerosis This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Melanie Ward interviews Dr. Nicholas Schwab about his Neurology: Neuroimmunology & Neuroinflammation paper on therapy with natalizumab and how it is associated with high JCV sero-conversion and rising JCV index values. Dr. Ted Burns is interviewing Sandi Moriarity and Andy Lucas for our "What's Trending" feature of the week about their positions and responsibilities with the Neurology podcast. In the next part of the podcast Dr. Ruth Ann Marrie interviews Dr. Brenda Banwell about the topic of diagnosis of pediatric multiple sclerosis and acute disseminated encephalomyelitis.DISCLOSURES: Dr. Schwab received funding for travel expenses from Biogen Idec; received speaking honoraria from Novartis; has a patent for Usage of L-selectin as predictive marker for progressive multifocal leukoencephalopathy; and receives research support from the Deutsche Forschungsgemeinschaft German Research Foundation and University Münster, IMF.Dr. Ted Burns serves as Podcast Editor for Neurology; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Sandi Moriarity is Senior Production Editor, Neurology.Andy Lucas is Audio-Visual Administrator, American Academy of Neurology.Dr. Marrie serves as an editorial board member of Neurology and Multiple Sclerosis Journal; receives research support for clinical trials from Sanofi-Aventis, from the Canadian Institutes of Health Research, Research Manitoba, from Multiple Sclerosis Society of Canada and the National Multiple Sclerosis Society, from Multiple Sclerosis Scientific Foundation and from Consortium of Multiple Sclerosis Centers; received research support from the Public Health Agency of Canada.Dr. Banwell serves as an editorial board member of Neurology and Multiple Sclerosis and Related Disorders; serves on the scientific advisory board for Biogen Idec, Sanofi-aventis, Eli Lilly and Company, Novartis; served as a consultant to Biogen Idec, Eli Lilly and Company, Sanofi-aventis; spoken at an event supported by the Consortium of MS Centers; receives research support from the Multiple Sclerosis Society of Canada, Multiple Sclerosis Scientific Research Foundation, and the National Multiple Sclerosis Society.NO CME WILL BE OFFERED THIS WEEK.

Tele-neurology and tele-stroke - from September 2015 LOTWs

1) Neurology® Genetics: Late diagnosis of cerebral folate deficiency: Fewer seizures with folinic acid in adult siblings 2) e-Pearl topic: Stroke-like migraine attacks after radiation therapy (SMART) Syndrome3) Topic of the month: Neurology Today story about unraveling the genetics of Alzheimer disease and attending the 'Oscars of Science' This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Nathan Fountain interviews Dr. Dave Dyment about his Neurology: Genetics paper on late diagnosis of cerebral folate deficiency. Dr. Ilena George is reading our e-Pearl of the week about stroke-like migraine attacks after radiation therapy (SMART) syndrome. Dr. Ted Burns interviews Dr. Steve Ringel about a Neurology Today story on the topic of unraveling the genetics of Alzheimer disease and attending the 'Oscars of Science.' DISCLOSURES: Dr. Fountain performs clinical procedures as epileptologist (100% effort) at the University of Virginia Comprehensive Epilepsy Program; receives research support from UCB, SK Life Sciences, Inc., Sunovion Pharmaceuticals, Inc., Medtronic, Inc., NeuroPace, Inc. and the NIH.Dr. Ted Burns serves as Podcast Editor for Neurology; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. George serves on the editorial team for the Neurology Resident and Fellow Section.Dr. Hardy serves on the scientific advisory boards for Eisai Inc. and Eli Lilly and Company; is a Consultant for Eisai Inc.NO CME WILL BE OFFERED THIS WEEK.

1) Neurology® Neuroimmunology & Neuroinflammation: Vasculitis neuropathy following exposure to minocycline 2) e-Pearl topic: Primary progressive aphasia3) Topic of the month: Neurology Today story about a wearable EEG device This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Chafic Karam about his Neurology: Neuroimmunology & Neuroinflammation paper on vasculitis neuropathy following exposure to minocycline. Dr. Ilena George is reading our e-Pearl of the week about primary progressive aphasia. Dr. Ted Burns interviews Dr. Jacqueline French about a Neurology Today story on the topic of a wearable EEG device. DISCLOSURES: Dr. Ted Burns serves as Podcast Editor for Neurology; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Karam serves as Deputy Editor for Neurology Write Click; served on the editorial team for the Neurology® Resident and Fellow Section; received speaker honoraria from Nufactor, Inc.; received consulting honoraria from Lundbeck Inc.Dr. George serves on the editorial team for the Neurology Resident and Fellow Section.Dr. French is a consultant for Acorda Therapeutics, Anavex, Brabant Pharma, Bio-Pharm Solutions, Eisai Inc., GlaxoSmithKline, GW Pharma, Impax, Johnson and Johnson, Marinus Pharmaceuticals, Inc., Neusentis, Novartis, Pfizer Inc, Sage, Sunovion Pharmaceuticals Inc., SK Life Sciences, Supernus, Takeda, UCB Pharma, Upsher-Smith Laboratories, Inc., Ultragenyx, Vertex, Zogenix, and Zynerba, all consulting was on behalf of the Epilepsy Study Consortium, and fees are paid to the consortium and New York University receives salary support from the consortium; serves as Associate Editor for Epilepsia; serves as an Editorial board member for Lancet Neurology, Neurology Today and Epilepsy Currents; research support from Acorda Therapeutics, Alexza, LCGH, Eisai Inc., Lundbeck Inc, Pfizer Inc, SK Life Sciences, UCB Pharma, Upsher-Smith Laboratories, Vertex, NIH, and the Epilepsy Foundation.NO CME WILL BE OFFERED THIS WEEK.