Of all the mental illnesses, schizophrenia eludes us the most. No matter the strides scientists have made in neurological research nor doctors have made in psychiatric treatment, schizophrenia remains misunderstood, almost complacently mythologized. Without a reason for the illness, patients feel even more alienated than they already do, families are left hopeless, and doctors struggle to provide accurate care. Steven Lesk, though, after a medical career dedicated to those affected by schizophrenia and a determination to find the answer to its existence, presents a groundbreaking theory that will forever change the lives of the mentally ill. 

In Footprints of Schizophrenia: The Evolutionary Roots of Madness (Prometheus, 2023), Lesk threads evolutionary evidence with neurological evidence, turning the mysteries of our minds into a tapestry of logic. With his breakthrough theory and this unprecedented book, Lesk will invite necessary cultural dialogue about this stigmatized illness, provoke new psychiatric and pharmacological research, and provide unequivocal comfort to those afflicted and affected by schizophrenia.

Lesk's "primitive organization theory" is based in human evolution, from Neanderthals to Homo sapiens, and the specific changes to our brains after the emergence of language. We have existed in human-like form for six million years, but we've only had language for 50,000; within the vast span of evolutionary time, that's hardly any time at all. Lesk elucidates us to the hormones affected by language, especially dopamine, and with brilliant clarity, connects human evolution, our brain affected by language, and those with schizophrenia whose dopamine doesn't flow in our new, adaptive way. In other words, the twenty million people who have schizophrenia in the world don't suppress dopamine in the way evolution has trained us, so their brains don't process language well and function as if they're in a hallucinatory, delusional dream state. Not only will Lesk's theory focus treatment efforts for schizophrenia, but it will also affect that of other dopamine-related mental illnesses like Alzheimer's, Parkinson's, Huntington's chorea, Tourette's, ADD, and more. Publishing Lesk's work will usher in a new era of psychiatric understanding, one that the field and the public desperately needs.

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There are many routes to mental well-being. In this groundbreaking book, neuroscientist Camilla Nord offers a fascinating tour of the scientific developments that are revolutionising the way we think about mental health, showing why and how events--and treatments--can affect people in such different ways.

In The Balanced Brain: The Science of Mental Health (Princeton UP, 2024), Nord explains how our brain constructs our sense of mental health--actively striving to maintain balance in response to our changing circumstances. While a mentally healthy brain deals well with life's turbulence, poor mental health results when the brain struggles with disruption. But just what is the brain trying to balance? Nord describes the foundations of mental health in the brain--from the neurobiology of pleasure, pain and desire to the role of mood-mediating chemicals like dopamine, serotonin and opioids. She then pivots to interventions, revealing how antidepressants, placebos and even recreational drugs work; how psychotherapy changes brain chemistry; and how the brain and body interact to make us feel physically (as well as mentally) healthy. Along the way, Nord explains how the seemingly small things we use to lift our moods--a piece of chocolate, a walk, a chat with a friend--work on the same pathways in our brains as the latest treatments for mental health disorders.

Understanding the cause of poor mental health is one of the crucial questions of our time. But the answer is unique to each of us, and it requires finding what helps our brains rebalance and thrive. With so many factors at play, there are more possibilities for recovery and resilience than we might think.

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Your mental health is as important as your physical health and, in times of stress, it's vital to have enhanced cognition and reserves of resilience. Brain Boost: Healthy Habits for a Happier Life (Cambridge UP, 2025) is packed with practical tips, based on scientific evidence, that will teach you how to implement lifestyle strategies that will improve your brain health, cognition, and overall wellbeing. Covering the benefits of exercise, diet, sleep, social interactions, kindness, mindfulness, and learning, you will discover how adopting habits to improve these areas of your life at an early age will lead to a longer, healthier life. Embracing these simple strategies to prioritise your brain health and wellbeing is essential for a fulfilling life, with lifestyle choices playing a significant role in promoting resilience, creativity, and overall quality of life across all ages. For anyone seeking to lead a fulfilling life through happiness, health, and personal growth, this is the book for you.

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How did humans come to be who we are? In his marvelous, eccentric, and widely lauded book Being a Beast, legal scholar, veterinary surgeon, and naturalist extraordinaire Charles Foster set out to understand the consciousness of animal species by living as a badger, otter, fox, deer, and swift. Now, he inhabits three crucial periods of human development to understand the consciousness of perhaps the strangest animal of all—the human being.

To experience the Upper Paleolithic era—a turning point when humans became behaviorally modern, painting caves and telling stories, Foster learns what it feels like to be a Cro-Magnon hunter-gatherer by living in makeshift shelters without amenities in the rural woods of England. He tests his five impoverished senses to forage for berries and roadkill and he undertakes shamanic journeys to explore the connection of wakeful dreaming to religion. For the Neolithic period, when humans stayed in one place and domesticated plants and animals, forever altering our connection to the natural world, he moves to a reconstructed Neolithic settlement. Finally, to explore the Enlightenment—the age of reason and the end of the soul—Foster inspects Oxford colleges, dissecting rooms, cafes, and art galleries. He finds his world and himself bizarre and disembodied, and he rues the atrophy of our senses, the cause for much of what ails us.

Drawing on psychology, neuroscience, natural history, agriculture, medical law and ethics, Being a Human: Adventures in Forty Thousand Years of Consciousness (Metropolitan Books, 2021) is one man’s audacious attempt to feel a connection with 45,000 years of human history. This glorious, fiercely imaginative journey from our origins to a possible future ultimately shows how we might best live on earth—and thrive.

Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at [email protected].

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This interview is an exception to our “single author monographs” rule, because the edited collection that is its topic is an intellectual achievement worth making an exception for in over 12 years of New Books in Philosophy podcasts. Emotion Theory: The Routledge Comprehensive Guide: Volume I and Volume II (Routledge, 2024) is a two-volume compendium of 62 chapters on emotion theory written by 101 leading theorists from philosophy, psychology, biology, sociology, neuroscience, and other fields, all grappling with the question: What is an emotion? Editor Andrea Scarantino, who is a professor of philosophy at George State University, has compiled a synoptic and thematically organized collection that covers the history of emotion theory, the main contemporary theories of emotions, individual chapters on 35 distinct emotions, and more. The volumes bring together theorists from distinct disciplines that don’t normally engage with each others’ work, and provide readers with a one-stop-shop for clearly written introductions to the current states of play in emotion research.

Andrea Scarantino is Professor of Philosophy at Georgia State University, where he has taught since 2005.

Carrie Figdor is professor of philosophy at the University of Iowa.

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People with dementia are uniquely qualified to discuss the challenges of their condition and the features of effective support, but their voices are all too often drowned out in research and debates about policy. According to People with Dementia at the Heart of Research: Co-Producing Research through The Dementia Enquirers Model (Jessica Kingsley Publishers, 2024) by Rachael Litherland & Philly Hare, it's time for that to change.

Dementia Enquirers is an ambitious and novel programme of work which has tested out what it means for people with dementia to lead research and has developed a new 'driving seat' approach to co-research.

This ground-breaking book features 26 research projects led by groups of people with dementia, supported by group facilitators and academics, to make their voices heard. Topics include giving up driving, GP dementia reviews, living alone with dementia, and using AI platforms such as smart speakers. The book also describes how people with dementia shaped the entire programme, and addressed head-on issues such as ethics approval processes and complex research language. The book is a key read for anyone involved in dementia support, this research brings the voices of people with dementia to the fore to explore their experiences of researching the condition.

This interview was conducted by Dr. Miranda Melcher whose new book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars.

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The question of whether mental disorders are disorders of the brain has led to a long-running and controversial dispute within psychiatry, psychology and philosophy of mind and psychology. While recent work in neuroscience frequently tries to identify underlying brain dysfunction in mental disorders, detractors argue that labelling mental disorders as brain disorders is reductive and can result in harmful social effects.

Are Mental Disorders Brain Disorders? (Routledge, 2024) brings a much-needed philosophical perspective to bear on this important question. Anneli Jefferson argues that while there is widespread agreement on paradigmatic cases of brain disorder such as brain cancer, Parkinson's or Alzheimer’s dementia, there is far less clarity on what the general, defining characteristics of brain disorders are. She identifies influential notions of brain disorder and shows why these are problematic. On her own, alternative, account, what counts as dysfunctional at the level of the brain frequently depends on what counts as dysfunctional at the psychological level. On this notion of brain disorder, she argues, many of the consequences people often associate with the brain disorder label do not follow. She also explores the important practical question of how to deal with the fact that many people do draw unlicensed inferences about treatment, personal responsibility or etiology from the information that a condition is a brain disorder or involves brain dysfunction.

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In his marvelous new book, When Animals Dream: The Hidden World of Animal Consciousness (Princeton UP, 2023), David Peña-Guzmán (SF State as well as the lovely philosophical podcast Overthink) offers up something new in animal studies--"a philosophical interpretation of biological subjectivity." Although we share no linguistic schema with animals there is lots more evidence than just YouTube (octopuses, dogs, signing chimpanzees, brain scans of dreaming birds etc) to suggest oneiric behaviors and underlying mental states occur all over the animal kingdom. So, David discusses with John his interest in using dreaming as a window into consciousness. Here is what it means that we are not alone in our dreams...

David details the "flattening and impoverishing effect on the natural sciences" wrought by 20th century behaviorist paradigms. He also expresses skepticism about the likelihood of AI ever achieving more than a "zombie" state; it now and perhaps always will profoundly differ from animals' varied experiences of our shared world.

The biological commonality that most strikes David is the idea it is logically inconceivable that there might be a dreamer devoid of consciousness or sentience. Dreaming, he argues may be the key to acknowledging animal's "moral considerability"--the right to have their consciousness, sentience and in the deepest sense their standing taken into account. . Finally David admits to a feeling of tragedy in writing this book: he has had to engage with experimentation that crosses boundaries in animal treatment in order to make the case for those boundaries. He understands his decision as tragic because either way--to engage or to ignore the science--would be to lose something.

Mentioned in the episode:

• New Wave of "inner space" SF authors who focus on the alien nature of humanity itself: J. G. Ballard, Philip K. Dick, and John's hero Ursula Le Guin.

Recallable Books:

Listen and Read here.

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Francisco Aboitiz is a professor at the Medical School and the director of the Interdisciplinary Center for Neuroscience at Pontificia Universidad Católica de Chile. A History of Bodies, Brains, and Minds: The Evolution of Life and Consciousness (MIT Press, 2024) tells the story of life and nervous systems. It introduces the conceptual framework and terminology of evolution, gives a great overview of our current knowledge and a thorough discussion of open questions.

The first part defines two basic concepts: evolution and life. Surprisingly, we learn that the first definition is more straightforward. If you are challenged by some terminology in the later chapters - like phylogeny, ontogeny, or the different types of homology - it is highly recommended to revisit the definitions in the first chapter.

The story begins in the second part. Chapter 3 introduces multiple theories on how the first cells might have appeared. In the next chapter, these cells start to form more complex, multicellular organisms. Chapter 5 is dedicated to the main characteristics and early history of neurons.

In the third part, we get acquinted with more complex animals. In chapter 6 with the bilaterians, in chapter 7 and 8 with the vertebrates and their nervous system, in chapter 9 with mammals. Chapter 10 provides a deep dive into the neocortex and its role in cognition.

The fourth part of the book is about "a singular ape". Chapter 11 describes the history of primates, focusing on Hominins. It goes into details on various aspects like walking, the growth of brains, toolmaking, and social life. Chapter 12 describes the evolution of vocal communication. Chapter 13 discusses how speech has influenced communication and social life. Chapter 14 explores numerous open questions around consciousness. How to define it? When and how did it emerge in evolution? Which animals are conscious and in which ways? After this long history, chapter 15 arrives in the present and the future. What are some current evolutionary trends? How do cultural and technological changes influence our nervous systems?

In our conversation with Professor Aboitiz, we focused on a few remarkable milestones in this story. For start, he outlined some theories how life might have begun.

Then a huge jump in time followed: How the first mammals appeared and survived in a world dominated by dinosaurs. Professor Aboitiz elaborated on how the brains of mammals differ from the brains of other vertebrates. He described the cerebral cortex, a new part in the mammalian brain. The role of senses changed significantly: The early mammals had worse vision, but better smell, touch, and audition compared to other vertebrates. Changes in the anatomy of the head and neck supported these more developed senses. The enhanced olfactory system is also related to the hippocampus, where some new skills appeared: advanced spatial orientation and short-term memory.

The next milestone we discussed in detail is the appearance of language. Professor Aboitiz shared some fascinating facts about the vocal communication of birds and primates. He explained the connection between toolmaking and language. He described the speech loop and the connection between working memory and talking. He proposes that manual gestures and vocal communication have evolved together, and communication has always been multi-modal.

The last part of our conversation focused on the current and future situation. How culture and technology has changed our nervous system, e.g. how a brain area is particularly involved in reading. Professor Aboitiz also discussed the more recent technological innovations and their effects on society and the environment. He introduced the social projects conducted by the Interdisciplinary Center for Neuroscience. The project RIEN (Robótica Integral Educativa & Neurociencia) facilitates workshops where kids work in teams with rotating roles to build and program robots.

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In Successful Aging: A Neuroscientist Explores the Power and Potential of Our Lives (Dutton Books, 2020), Daniel J. Levitin delivers powerful insights:

• Debunking the myth that memory always declines with age

• Confirming that “health span”—not “life span”—is what matters

• Proving that sixty-plus years is a unique and newly recognized developmental stage

• Recommending that people look forward to joy, as reminiscing doesn’t promote health

Levitin looks at the science behind what we all can learn from those who age joyously, as well as how to adapt our culture to take full advantage of older people’s wisdom and experience. Throughout his exploration of what aging really means, using research from developmental neuroscience and the psychology of individual differences, Levitin reveals resilience strategies and practical, cognitive- enhancing tricks everyone should do as they age.

Successful Aging inspires a powerful new approach to how readers think about our final decades, and it will revolutionize the way we plan for old age as individuals, family members, and citizens within a society where the average life expectancy continues to rise. 

Victoria Reedman is a resident doctor in Toronto studying neurology with some health systems work on the side.

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