King Charles welcomes US President Donald Trump on his second state visit to Britain. There was plenty of pomp and pageantry but also protests.

Also on the programme: we'll hear from inside Gaza City where thousands of people are trying to escape heavy Israeli bombardment; and a powerful new AI tool which can estimate the long-term risk of more than a thousand diseases.

(Photo: US President Donald Trump and King Charles III watch a flypast by the RAF Red Arrows during a Beating Retreat military ceremony at Windsor Castle, Berkshire, on day one of the president's second state visit to the UK. Credit: PA)

Donald Trump has begun the first full day of his unprecedented second state visit to Britain. Also on the programme, Israel says it will open another route out of Gaza City, after the main road south became clogged with vehicles; and, Pablo Picasso takes to the stage.

(Photo: US President Donald Trump and King Charles III walk during the ceremonial welcome at Windsor Castle, Berkshire, on day one of the president's second state visit to the UK. Picture date: Wednesday September 17, 2025. Jonathan Brady/Pool via REUTERS)

The Israeli army embarks on an major ground assault into Gaza City. One resident tells us she can't bear the thought of fleeing again.

The offensive comes on the day a UN commission says Israel has committed genocide in Gaza.

Also on the programme: the Hollywood legend Robert Redford has died at the age of 89. We’ll hear from his friend, film producer Lord David Puttnam; and what's changed in Iran three years on from the death of a young Kurdish woman.

(Photo: Displaced Palestinians, fleeing northern Gaza due to an Israeli military operation, move southward after Israeli forces ordered residents of Gaza City to evacuate to the south, in the central Gaza Strip September 16, 2025. Credit: REUTERS/Mahmoud Issa)

A United Nations commission of inquiry says Israel has committed genocide against Palestinians in Gaza. Also on the programme, three years on from the death of Mahsa Amini, we look at the state of Iran's women-led uprising; and, the Hollywood actor and director Robert Redford has died.

(Photo: Israeli airstrikes on Gaza City - 14 Sep 2025 MOHAMMED SABER/EPA/Shutterstock)

The BBC reports from inside Afghanistan on the loss of access to maternity care, after US aid cuts. Also on the programme, Israel's Prime Minister Benjamin Netanyahu has said US-Israeli relations have "never been stronger", as US Secretary of State Marco Rubio visits to discuss the war in Gaza following Israel's attack on Hamas members in Qatar; and, the Emmy awards rewards its youngest every winner.

(Photo: Aakriti Thapar / BBC)

US Secretary of State Marco Rubio is visiting to discuss the war in Gaza following Israel's attack on Hamas members in Qatar. His visit comes as Israeli forces continue to destroy residential buildings in Gaza City, forcing thousands to flee ahead of an expected ground offensive to seize the city.

Also on the programme: We hear from an American city sitting on the border between two US states with opposing abortion laws three years on from US citizens losing their constitutional right to abortion nationwide; and we'll speak to one of the organisers of the protests in Nepal about why she is backing the country's interim prime minister.

(Photo: U.S. Secretary of State Marco Rubio and Israeli Prime Minister Benjamin Netanyahu visit the Western Wall, Judaism's holiest prayer site, in Jerusalem's Old City on September 14, 2025. Credit: REUTERS/Nathan Howard/Pool)

As the US secretary of state, Marco Rubio, begins his visit to Israel, he has once again criticised the Israeli strike on Qatar. We ask whether this will bring about a policy change in Israel and how the Gulf states will react to the strike.

Also in the programme, fighter jets are scrambled as Romania becomes the second NATO country to report an incursion into its airspace by a Russian drone. And the rock band, Queen, gives their first symphonic performance of their rock operetta Bohemian Rhapsody at the Last Night of the BBC Proms.

Credit: Photo by ABIR SULTAN/EPA/Shutterstock (15485623ao) US Secretary of State Marco Rubio (L) and Israeli Prime Minister Benjamin Netanyahu (R) visit the Western Wall in the Old City of Jerusalem, 14 September 2025

Nepal's major political parties have demanded parliament be reinstated a day after it was dissolved following deadly anti-corruption protests. Anti-government protests this week sparked by a now reversed social media ban saw at least fifty one people killed and more than a thousand injured.

Also on the programme: 100,000 people have joined a far- right march in London featuring violent clashes, calls to send migrants home, and a message of support from Elon Musk; and we'll hear about the three Austrian nuns who have run away from the retirement home to return to their former convent.

(People take part in a candlelight vigil in memory of people who died during the protest against anti-corruption triggered by a social media ban, which was later lifted, in Kathmandu, Nepal, September 13, 2025. Credit: REUTERS/Navesh Chitrakar)

The widow of Charlie Kirk, a right-wing political activist in the US, says she will never let his legacy die. She said her cries would echo around the world like a battle cry. Charlie Kirk was President Donald Trump's bridge to young Republicans. We ask if his death is likely to aggravate political tension in the US?

Photo: Charlie Kirk with his wife, Erika Kirk, celebrating Trump’s inauguration in Washington, D.C., in January Credit: Getty

US officials say they've arrested a 22-year old man suspected of shooting dead the prominent right wing youth leader, Charlie Kirk. Also on the programme, a Nobel prize-winner weighs in on the Trump administration's vaccine policies; and, a new push to get museum visitors to spend more time in front of art.

(Photo :A Washington County sheriff’s deputy joins Washington City police officers outside a residence in Washington, Utah, associated with Tyler Robinson, the suspect in the fatal shooting of U.S. conservative commentator Charlie Kirk during an event at Utah Valley University, U.S., September 12, 2025. REUTERS/Steve Marcus)