Moscow says Ukraine has launched American-supplied long-range missiles into the country, a day after Washington gave its permission for such attacks.

Also on the programme: we speak to the wife of one of the 45 pro-democracy activists in Hong Kong who have been given long jail terms; and, Gisèle Pelicot, the woman at the centre of france's mass rape trial, makes her final statement to the court.

(Photo: US Army Tactical Missile System (ATACMS) firing a missile into the East Sea during a South Korea-US joint missile drill in 2017. Credit: Getty Images, file photo)

Russia has vowed to respond if Ukraine uses US long-range ATACMS missiles to hit its territory. We'll hear views from Ukraine, Russia and Germany.

(Photo: A resident carries outs items from his house heavily damaged by a Russian missile strike on Odesa, Ukraine. Credit: REUTERS/Nina Liashonok)

President Biden's decision to allow Ukraine to hit Russia with American long-range missiles has prompted scorn in Moscow. What difference will the move by the outgoing administration make - and might other Western allies follow the US' lead?

Also in the programme: We'll hear from Delhi, the Indian city which gasps under unrelenting toxic smog; and he leaders of the world's most powerful countries meet in Brazil - but are they just marking time until Donald Trump returns?

(Photo shows a file photo of a missile from the Army Tactical Missile System, a surface-to-surface ballistic system, similar to what Ukraine is going to use. Credit: White Sands Missile Range Public Affairs)

US media say President Biden has made a major policy change, by letting Ukraine use long-range missiles to hit targets deep inside Russia. Ukraine's leader, Volodymyr Zelensky, has long called for the change. There's been no confirmation from the White House.

Also in the programme: An Israeli airstrike in central Beirut is reported to have killed Hezbollah’s media chief; Russian opposition protestors take to the streets in Berlin; and a proposal in the new Zealand parliament, which would impact the rights of Maoris there.

(Photo: White Sands Missile Range Public Affairs)

Russia has again targeted Ukraine’s energy infrastructure; we hear from the governor of one of the regions that has been hit.

Also in the programme: Israeli airstrikes on Beit Lahiya in northern Gaza kill at least forty-six people in a multi-storey building; why Maoris and their supporters are marching to protest against a proposed change to New Zealand’s founding treaty; and the drama that portrays former German Chancellor Angela Merkel as an amateur sleuth.

(IMAGE: Firefighters work at the site of a critical infrastructure facility hit by a Russian missile strike, in Vinnytsia region, Ukraine November 17, 2024 / CREDIT: Press service of the State Emergency Service of Ukraine in Vinnytsia region/Handout via REUTERS)

US and Chinese leaders to discuss “delicate transition” in Lima as President Biden holds his last talks with Chinese President Xi Jinping on sides of APEC summit.

(IMAGE: President Biden the APEC summit in Peru. CREDIT: Reuters/Leah Millis)

President Zelensky says that with Donald Trump in power in the US, Ukraine's war with Russia will end sooner than expected: does this signal a big change in his thinking? We hear from a Ukrainian MP.

Also in the programme: we hear live from South Africa where a stand-off continues between police and illegal miners at an abandoned gold mine; and we follow the Afghans leaving their homeland in the hope of making it to the UK.

(IMAGE: Ukraine's President Volodymyr Zelensky attends a press conference after the 5th summit of the European Political Community (EPC) in Puskas Arena in Budapest, Hungary, 07 November 2024 / CREDIT: Zoltan Balogh /EPA-EFE/REX/Shutterstock)

European vaccine shares fall on the nomination by Donald Trump of vaccine sceptic Robert F Kennedy Junior as US Health Secretary. We look at his views on food, nutrition and agriculture.

Also on the programme: why the South African authorities are determined to starve thousands of illegal miners to force them out of a mine; and the man caught smuggling hundreds of tarantulas and bullet ants by plane at great risk to himself.

(Photo: Robert F Kennedy Jr speaks at Bitcoin 2024 in Nashville in July. Credit: Reuters)

Donald Trump is continuing to build a controversial administration, having picked vaccine sceptic and former independent presidential candidate Robert F Kennedy Jr as his health secretary. Kennedy, commonly known by his initials RFK Jr, has a history of spreading health information that scientists say is false. We hear from a senior adviser to the Trump 2024 election campaign, as well as a former CDC director with serious concerns about the choice.

Also on the programme: the latest from the UN climate talks in Azerbaijan, as well as the remarkable discovery of a pre-historic ecosystem in the Italian Alps.

(Picture: Robert F. Kennedy Jr. attends the America First Policy Institute gala at Mar-A-Lago in Florida Credit: REUTERS/Carlos Barria)

Donald Trump has nominated former Republican US Congressman Matt Gaetz for the role of US attorney-general.

Photo: Former US Republican Congressman Matt Gaetz speaks at a campaign rally for Donald Trump in Henderson, Nevada U.S. 31st October 2024. Credit: Reuters/Mike Blake