Tom Sutcliffe discusses the history of pain with the historian Joanna Bourke, who explores how our attitude to suffering has changed through the centuries. The former Conservative MP, Norman Fowler, looks back at the public health campaign that revolutionised the fight against HIV and Aids in Britain in the 1980s, and how discrimination and political expediency are hampering prevention and treatment around the world today. The Director of the Wellcome Trust, Jeremy Farrar remembers when he was a junior doctor and patients were dying of Aids because there was no treatment. He warns that the overuse and misuse of anti-biotic drugs could herald a return to the days of untreatable diseases.

Producer: Katy Hickman.