Melvyn Bragg and guests discuss penicillin, discovered by Alexander Fleming in 1928. It is said he noticed some blue-green penicillium mould on an uncovered petri dish at his hospital laboratory, and that this mould had inhibited bacterial growth around it. After further work, Fleming filtered a broth of the mould and called that penicillin, hoping it would be useful as a disinfectant. Howard Florey and Ernst Chain later shared a Nobel Prize in Medicine with Fleming, for their role in developing a way of mass-producing the life-saving drug. Evolutionary theory predicted the risk of resistance from the start and, almost from the beginning of this 'golden age' of antibacterials, scientists have been looking for ways to extend the lifespan of antibiotics.WithLaura Piddock
Professor of Microbiology at the University of BirminghamChristoph Tang
Professor of Cellular Pathology and Professorial Fellow at Exeter College at the University of OxfordAndSteve Jones
Emeritus Professor of Genetics at University College, LondonProducer: Simon Tillotson.

Melvyn Bragg and guests discuss penicillin, discovered by Alexander Fleming in 1928. It is said he noticed some blue-green penicillium mould on an uncovered petri dish at his hospital laboratory, and that this mould had inhibited bacterial growth around it. After further work, Fleming filtered a broth of the mould and called that penicillin, hoping it would be useful as a disinfectant. Howard Florey and Ernst Chain later shared a Nobel Prize in Medicine with Fleming, for their role in developing a way of mass-producing the life-saving drug. Evolutionary theory predicted the risk of resistance from the start and, almost from the beginning of this 'golden age' of antibacterials, scientists have been looking for ways to extend the lifespan of antibiotics. With Laura Piddock Professor of Microbiology at the University of Birmingham Christoph Tang Professor of Cellular Pathology and Professorial Fellow at Exeter College at the University of Oxford And Steve Jones Emeritus Professor of Genetics at University College, London Producer: Simon Tillotson.

Penicillin

Spanning history, religion, culture, science and philosophy, In Our Time from BBC Radio 4 is essential listening for the intellectually curious. In each episode, host Melvyn Bragg and expert guests explore the characters, events and discoveries that have shaped our world. 
 
History fans can learn about pivotal wars and societal upheavals, such as the rise and fall of Napoleon, the Sack of Rome in 1527, and the political intrigue of the Russian Revolution. Those fascinated by the lives of kings and queens can journey to Versailles to meet Marie Antoinette and Louis XIV the Sun King, or to Ancient Egypt to meet Cleopatra and Nerfertiti. Or perhaps you’re looking to explore the history of religion, from Buddhism’s early teachings to the Protestant Reformation.
 
If you’re interested in the stories behind iconic works of art, music and literature, dive in to discussions on the artistic genius of Michelangelo's Sistine Chapel and Van Gogh’s famous Sunflowers. From Gothic architecture to the works of Shakespeare, each episode of In Our Time offers new insight into humanity’s cultural achievements.
 
Those looking to enrich their scientific knowledge can hear episodes on black holes, the Periodic Table, and classical theories of gravity, motion, evolution and relativity. Learn how the discovery of penicillin revolutionised medicine, and how the death of stars can lead to the formation of new planets. 
 
Lovers of philosophy will find episodes on the big issues that define existence, from free will and ethics, to liberty and justice. In what ways did celebrated philosophers such as Mary Wollstonecraft and Karl Marx push forward radical new ideas? How has the concept of karma evolved from the ancient Sanskrit texts of Hinduism to today? What was Plato’s concept of an ideal republic, and how did he explore this through the legend of the lost city of Atlantis?
 
In Our Time celebrates the pursuit of knowledge and the enduring power of ideas.

History

Spanning history, religion, culture, science and philosophy, In Our Time from BBC Radio 4 is essential listening for the intellectually curious. In each episode, host Melvyn Bragg and expert guests explore the characters, events and discoveries that have shaped our world. History fans can learn about pivotal wars and societal upheavals, such as the rise and fall of Napoleon, the Sack of Rome in 1527, and the political intrigue of the Russian Revolution. Those fascinated by the lives of kings and queens can journey to Versailles to meet Marie Antoinette and Louis XIV the Sun King, or to Ancient Egypt to meet Cleopatra and Nerfertiti. Or perhaps you’re looking to explore the history of religion, from Buddhism’s early teachings to the Protestant Reformation. If you’re interested in the stories behind iconic works of art, music and literature, dive in to discussions on the artistic genius of Michelangelo's Sistine Chapel and Van Gogh’s famous Sunflowers. From Gothic architecture to the works of Shakespeare, each episode of In Our Time offers new insight into humanity’s cultural achievements. Those looking to enrich their scientific knowledge can hear episodes on black holes, the Periodic Table, and classical theories of gravity, motion, evolution and relativity. Learn how the discovery of penicillin revolutionised medicine, and how the death of stars can lead to the formation of new planets. Lovers of philosophy will find episodes on the big issues that define existence, from free will and ethics, to liberty and justice. In what ways did celebrated philosophers such as Mary Wollstonecraft and Karl Marx push forward radical new ideas? How has the concept of karma evolved from the ancient Sanskrit texts of Hinduism to today? What was Plato’s concept of an ideal republic, and how did he explore this through the legend of the lost city of Atlantis? In Our Time celebrates the pursuit of knowledge and the enduring power of ideas.

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