Dr Kimberley Haines, Vice Chair of ANZICS Victorian Branch and ICU Physio at Western Health joins Dan and Jane to discuss survival following ICU admissions.

Dr Kimberley discusses her journey to research, what happens to patients following ICU discharge and how we can improve the ICU journey for patients, staff and family.

Jane and Dan caught up with Professor Jason Roberts, NHMRC Practitioner Fellow at The University of Queensland and Consultant Clinical Pharmacist at the Royal Brisbane and Women's Hospital. Jason is a senior member of the Burns Trauma and Critical Care Research Centre within the University of Queensland Centre for Clinical Research and is Director of the Centre for Translational Anti-infective Pharmacodynamics in School of Pharmacy where he is also Chair of the research Strategies Committee.

We could have talked to Jason all day. In part two of our two-part discussion on pharmacokinetic modelling of antimicrobials we talk about:

• different pharmacodynamic models for antimicrobials: concentration, time and AUC dependant
• the clinical evidence for using pharmacokinetic and pharmacodynamic modelling
• future directions for clinical pharmacokinetics

Jane and Dan caught up with Professor Jason Roberts, NHMRC Practitioner Fellow at The University of Queensland and Consultant Clinical Pharmacist at the Royal Brisbane and Women's Hospital. Jason is a senior member of the Burns Trauma and Critical Care Research Centre within the University of Queensland Centre for Clinical Research and is Director of the Centre for Translational Anti-infective Pharmacodynamics in School of Pharmacy where he is also Chair of the research Strategies Committee.

We could have talked to Jason all day. In part one of our two-part discussion on pharmacokinetic modelling of antimicrobials we talk about:

• Jason's pathway to a research career and the projects that his team are currently working on
• The patients and pathogens that benefit from individualised dosing of antimicrobials
• The narrowing therapeutic indices of some antimicrobials
• Some under-recognised adverse effects of beta-lactam antibiotics
• how to apply pharmacokinetics and individualised dosing in everyday practice

Dan caught up with NAPSA President Sandra Minas at the inaugural SHPA-NAPSA symposium in Melbourne on Friday. We discussed issues facing students, the results of the latest NAPSA survey and key programs being rolled out by NAPSA.

We learn that despite concerns about graduate numbers, the rise of discounters and low pay, almost all pharmacy students are dedicated to their profession, and are looking forward to their careers.

Jane and Dan spoke to Horst Thiele from the Primary Care and Transitions of Care specialty practice leadership group.

We asked Horst about the barriers and opportunities for pharmacists to assist patients at transitions of care and the evidence base for these services.

Dan and Jane are joined by Clarissa Rentsch to discuss updates on Inflammatory Bowel Disease with Clarissa Rentsch.

Clarissa is the Senior Pharmacist - Gastroenterology at Alfred Health, and discusses new therapy for IBD, the developing role for TDM in the management of this disease and her innovative clinic based role at The Alfred.

We discuss:

• Commencing therapy with and monitoring purine analogues
• Infliximab - its expanding role in therapy, and the emerging field of TDM for biologicals
• Clarissa's innovative role in the clinics, including dose adjustment and monitoring.

Jane and Dan spoke to Dr Manuel Serrano Santos, Lecturer of Pharmacy at QUT and member of the editorial committee for the third edition of Don't Rush to Crush.

We spoke to Manuel about:

• his role as a specialist dysphagia pharmacist
• what goes wrong when medicines are modified inappropriately
• common reasons for making mistakes when modifying medicines

This is a reboot of our first ever episode: Antibiotic Allergies with Dr Jason Trubiano

For our special 50th Episode we first discuss some things we've learned from making the podcast. Then Jane caught up with Dr Jason Trubiano, an Infectious Diseases Physician from Austin Health. Jason appeared on our first episode, and in Episode 50 we get an update on the world of antibiotic allergies and bust some more myths.

We're also re-releasing Episode One as a special 50th Episode treat.

Jane caught up with two members of the writing group for the recently updated Therapeutic Guidelines: Cardiovascular. Confusingly, they are also called Jane and Dan! Jane O'Connor is an Editor at Therapeutic Guidelines and Dr Daniel Scherer is a Cardiologist and PhD Candidate at the South Australian Health and Medical Research Institute.