In this episode, we explore the use of high-dose olanzapine as a potential alternative to clozapine for treatment-resistant schizophrenia. We discuss a systematic review that examines the efficacy and safety of olanzapine doses above the FDA-approved maximum. Could high-dose olanzapine be a viable option when patients refuse clozapine?

Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D.

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• Is High-Dose Olanzapine an Option for Treatment-Resistant Schizophrenia?