On this podcast episode, I discuss levofloxacin pharmacology, adverse effects, boxed warnings, interactions, and much more.

Levofloxacin is well known to cause QTc prolongation and many drugs can increase this risk such as antiarrhythmics, citalopram, antipsychotics, and many more.

Binding interactions are important when discussing levofloxacin pharmacology. Calcium, iron, magnesium, and many other cations can block the absorption of this medication.

I discuss tendon rupture in relation to levofloxacin use and what factors may increase the risk of this rare adverse effect.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

On this podcast episode, I discuss darifenacin pharmacology, adverse effects, drug interactions and much more.

CYP3A4 and CYP2D6 are important enzymes in relation to darifenacin. I breakdown the importance of these enzymes and how they can impact drug therapy.

Darifenacin has anticholinergic activity but affects the central nervous system less than other agents in its class such as oxybutynin and tolterodine.

Darifenacin’s pharmacology is selective for the Muscarinic-3 (M3) receptor in bladder tissue which helps reduce the risk for CNS adverse effects.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

In this podcast episode, I discuss naltrexone pharmacology, adverse effects, drug interactions, and much more.

Naltrexone is an opioid antagonist and can blunt the effects of opioid agonists. Because of this, the medication can be used to manage opioid use disorder.

Hepatotoxicity is a concern of naltrexone and because of this, it is recommended to monitor LFTs.

There is an injectable, long-acting formulation of naltrexone that can be used for opioid and alcohol use disorder treatment.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

On this podcast episode, I discuss acamprosate pharmacology, adverse effects, drug interactions, and much more!

Acamprosate’s most common adverse effect is diarrhea. It is a primary reason why patients will ask to stop taking this medication.

It is critical to assess renal function prior to using acamprosate. Dose adjustments are recommended when patients have a CrCl of less than 50 ml/min.

Unlike naltrexone, acamprosate avoids liver metabolism making it an alternative option in alcohol use disorder for patients who have liver impairment.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

On this podcast episode, I discuss alfuzosin pharmacology, adverse effects, drug interactions, and much more!

Alfuzosin is an alpha blocker used to help relieve the symptoms of BPH.

Low blood pressure is a possible adverse effect of alfuzosin and is more likely when combined with PDE-5 inhibitors like sildenafil.

CYP3A4 is an important enzyme in the metabolism of alfuzosin. Inhibitors of CYP3A4 can raise concentrations and increase the chance of alfuzosin toxicity.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

In this podcast episode, I discuss methadone pharmacology, adverse effects, drug interactions, and pharmacokinetics.

Methadone is a full opioid agonist that may be used for pain management and opioid use disorder.

Transitioning from methadone to another opioid is complicated. I discuss conversion in this podcast episode.

Methadone can increase the risk of QTc prolongation and also has a lot of drug interactions. I discuss them in detail in this podcast episode.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

On this podcast episode, I discuss meperidine pharmacology, adverse effects, pharmacokinetics, drug interactions, and much more!

Meperidine is an opioid that is seldom used due to neurotoxicity. I describe how this can happen in this podcast episode.

Meperidine has numerous drug interactions and using a CYP3A4 inhibitor may increase the risk for toxicity.

Seizures are a risk with meperidine due to its neurotoxic metabolite normeperidine. I discuss this further in this podcast episode.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

On this episode of the podcast, I cover guanfacine pharmacology, adverse effects, drug interactions, and much more.

Guanfacine is a central acting alpha-2 agonist that has the brand names of Tenex and Intuniv.

Because of guanfacine’s mechanism of action, it suppresses the sympathetic response leading to a drop in pulse and blood pressure.

It is important to remind patients that the onset of action is slow in the management of ADHD with guanfacine. I discuss this further in this podcast episode.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

On this podcast episode, I discuss fluvastatin pharmacology, adverse effects, pharmacokinetics, and much more.

Fluvastatin is only a low to moderate-intensity statin which explains its limited use compared to rosuvastatin or atorvastatin.

I discuss drug interactions in the podcast but one important one to recognize is drugs that can inhibit CYP2C9.

Fluvastatin is considered a lipophilic statin. I have previously discussed this on the Meded101 blog which you can find here.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101

In this episode, I discuss oxymorphone pharmacology, adverse effects, drug interactions, and more!

Oxymorphone is approximately 3 times more potent than morphine. I break down some common opioid comparisons in this episode.

Oxymorphone avoids many of the CYP interactions. I discuss some of the common interactions in this episode.

I discuss histamine release in relation to opioids and oxymorphone and specifically how this may impact our patients.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101