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Citalopram is an SSRI used in the management of depression, anxiety, OCD, and PTSD.
How do you manage the risk of citalopram causing QTc prolongation? I discuss it further in the podcast.
Omeprazole can inhibit CYP2C19 which affects the metabolism of citalopram. I discuss the clinical impacts of this interaction in the podcast.
Geriatric dosing with citalopram is recommended to be lower than traditional adult dosing. I discuss this further in the podcast.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.
Epoetin alfa is essential exogenous erythropoetin which can stimulate the production of red blood cells.
It is critical to ensure adequate iron stores when using EPO.
Risks for blood clots, strokes and heart attacks are critical to recognize with the use of epoetin.
Dosage adjustments with epoetin are typically made with respect to the amount of change in hemoglobin. I discuss this further in the podcast.
I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Dexamethasone has numerous possible indications such as asthma, chemotherapy-induced nausea and vomiting, and pain associated with inflammation.
Dexamethasone is more potent than prednisone. Approximately 0.75 mg of dexamethasone is equivalent to 5 mg of prednisone.
When using dexamethasone, recall that it can raise blood sugars. Monitor this closely in patients with diabetes.
A dexamethasone suppression test helps detect excessive endogenous production of cortisol.
I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
On this episode, I discuss sildenafil pharmacology, adverse effects, and important drug interactions.
Sildenafil’s most common and concerning adverse effect is in relation to its ability to lower blood pressure. I discuss this further in the podcast.
Sildenafil can cause rare visual changes that patients should be aware of and report immediately to their pharmacist or physician.
The sildenafil nitrate interaction is essential to know. I discuss it in this podcast episode.
I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
On this episode, I discuss codeine pharmacology and practical clinical practice pearls.
Codeine is metabolized by CYP2D6 to the active metabolite morphine. I discuss how this can be affected by genetics as well as other medications.
Constipation is a problem with codeine and all opioids in general. Education and making a plan with patients to combat this side effect is important.
Codeine is less potent than other opioids such as fentanyl, hydromorphone, and hydrocodone.
I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
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