What is ‘structure-based’ vaccine design? Before scientists used these techniques to design vaccines against Covid, they were testing them in the lab to combat RSV. Keren Landman joins the show to talk about how this respiratory virus endangers the lives of babies and the elderly. Then, we hear about an early RSV vaccine trial that cast a shadow over modern research, and how scientists, including our guests Jason McLellan and Barney Graham, later figured out how to create and stabilize a viral antigen’s spike protein to fight RSV. See omnystudio.com/listener for privacy information.

RSV: The Quest for a New Vaccine

Utopia or dystopia? It’s up to us.In the 21st century, powerful technologies have been appearing at a breathtaking pace—related to the internet, artificial intelligence, genetic engineering, and more. They have amazing potential upsides, but we can’t ignore the serious risks that come with them.Brave New Planet is a podcast that delves deep into the most exciting and challenging scientific frontiers, helping us understand them and grapple with their implications. Dr. Eric Lander, president and founding director of the Broad Institute of MIT and Harvard, is a geneticist, molecular biologist, and mathematician who was a leader of the Human Genome Project and for eight years served as a science advisor to the White House for President Obama. He’s also the host of Brave New Planet, and he’s talked to leading researchers, journalists, doctors, policy makers, activists, and legal experts to illuminate how this generation’s choices will shape the future as never before.Brave New Planet is a partnership between the Broad Institute, Pushkin Industries, and The Boston Globe's Opinion team.

Technology

Tech News

Podcasting

Gadgets

Software How-To

News

Science

The Happiness Lab’s Dr. Laurie Santos brings together other Pushkin hosts to mark the International Day of Happiness. Revisionist History’s Malcolm Gladwell talks about the benefits of the misery of running in a Canadian winter. Dr. Maya Shankar from A Slight Change of Plans talks about quieting her mental chatter. And Cautionary Tales host Tim Harford surprises everyone with the happiness lessons to be learned from a colonoscopy.
Hear more of The Happiness Lab HERE. See omnystudio.com/listener for privacy information.

Pushkin Hosts Celebrate World Happiness Day

Open-source innovation is the future of AI. In this episode of Smart Talks with IBM, Malcolm Gladwell and Tim Harford discuss the open-source AI community with Jeff Boudier, head of product and growth at Hugging Face. They chat about the history and future of open-source AI, its critical importance to AI progress, the IBM watsonx partnership with Hugging Face, and how businesses can leverage open-source AI for their specific needs.
Visit us at: https://www.ibm.com/smarttalks/
Learn more about the Hugging Face partnership: https://newsroom.ibm.com/2023-08-24-IBM-to-Participate-in-235M-Series-D-Funding-Round-of-Hugging-Face 
Learn more about the Google DeepMind paper referenced in this episode:  https://proceedings.neurips.cc/paper_files/paper/2017/file/3f5ee243547dee91fbd053c1c4a845aa-Paper.pdf
This is a paid advertisement from IBM. See omnystudio.com/listener for privacy information.

Hugging Face and watsonx: Why Open Source Is the Future of AI in Business

What can we learn from the centuries-long quest to eradicate smallpox, once the scourge of humanity? And how did it set the stage for all vaccines to come? First we meet Edward Jenner, a doctor in 18th century Britain who learned about the folk practice of “variolation” and found a safer way to inoculate people against smallpox. Then, Donald Hopkins of the Carter Center takes us back to the 1960s in Sierra Leone, where he discovered that successfully eradicating smallpox could be a feasible goal worldwide. Enjoy this episode from Incubation, another Pushkin podcast. See omnystudio.com/listener for privacy information.

Smallpox: Gone but Not Forgotten from Incubation

This excerpt from Pushkin's new audiobook, Higher Animals: Vaccines, Synthetic Biology, and the Future of Life, features the introduction to Michael Specter's exciting exploration into how MRNA vaccines have transformed the scientific landscape and helped spark a biotechnology revolution. Go buy yourself a copy at pushkin.fm, Audible, Apple Books, or anywhere audiobooks are sold. See omnystudio.com/listener for privacy information.

RSV: The Quest for a New Vaccine

Download our free app to listen on your phone