What if psychedelics could transform the way we treat trauma, chronic pain, and insomnia? This week, neuroscientist and psychedelic researcher Grace Blest-Hopley joins the show to break down the research on psychedelics and female biology. She discusses how psychedelics work in the brain, and the ways that psychedelic-assisted therapies might be beneficial for women in midlife.

Links to resources mentioned in this episode:

Hystelica’s resources on psychedelic retreats

The Heroic Hearts Project

Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics

Exploring the Therapeutic Effects of Psychedelics Administered to Military Veterans in Naturalistic Retreat Settings

The acute effects of classic psychedelics on memory in humans

Psilocybin with psychological support for treatment-resistant depression: six-month follow-up

Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression

Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial

Johns Hopkins study on psychedelics and Alzheimer’s

Note: In this show, we use “women” as shorthand for people with XX chromosomes. We understand sex and gender are more complex, and acknowledge the experiences we describe reach beyond that word.

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Maya Shankar, host of Pushkin's A Slight Change of Plans podcast, just released a new book, "The Other Side of Change". To celebrate, we're sharing an exclusive excerpt with the Pushkin community. It's about what first sparked Maya’s interest in change, and the story of a woman named Olivia Lewis.

Order “The Other Side of Change: Who We Become When Life Makes Other Plans” at changewithmaya.com/book, or wherever you like to buy books.

About The Other Side of Change:
Life has a way of thwarting our best-laid plans. Out of nowhere, we’re confronting the end of a relationship, an unexpected diagnosis, the loss of a job, or some other twist of fate. In these moments, it can feel like we’re free-falling into the unknown.

As a cognitive scientist, Maya Shankar has spent decades studying the human mind. When an unwanted change in her own life left her reeling, she sought out people who had navigated major disruptions. In "The Other Side of Change", Shankar tells their riveting, singular stories and weaves in scientific insights to illuminate universal lessons hidden within them.

When a big change happens to us, it can lead to profound change within us. The unique stresses and demands of being thrust into a new reality can lead us to uncover new abilities, perspectives, and values, transforming us in extraordinary ways. What if we saw moments of upheaval as an opportunity to reimagine who we can be, rather than as something to just endure? Whether you’re processing a past change, grappling with a present one, or bracing for a future one, this book is a wise and thought-provoking companion to help you discover who you can become on the other side of change.

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Wayfinder invites you to indulge in the art of travel through story, sensation, and self-discovery. Hosted by Daniel Scheffler, veteran travel writer, this immersive new series ventures beyond guidebooks and itineraries into the transformative journeys that reshape how we see the world and ourselves.

Rediscover the beauty and awe-inspiring moments that define life-changing travel. From swimming with whales in Tahiti to savoring local flavors and hidden traditions in Tunisia, each episode captures the heart and humor of adventure through the eyes of real travelers.

Every other week, join Daniel as he explores the experiences that can only be found when we follow our senses, trust our inner compass, and let curiosity lead the way.

Check out Daniel Scheffler's Substack: https://withoutmaps.substack.com/about

Follow iHeart's Ruby Studio: https://www.instagram.com/rubyiheart/?hl=en

Our Team:

Executive Producer: Ciara Kaiser

EP of Post Production: James Foster

Supervising Producer: Nakia Swinton

Story Producer: Ryan Amador

Post-Production: Siara Spreen

Theme Music: Max Hershenow

Show Art: Samantha Rayman

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Lili Taylor loves her acting career - but the emotional intensity of her work and the constant travel can take its toll. But Lili has found a way to relax and unwind - watching birds. 

As Lili explains in her new book Turning to Birds: The Power and Beauty of Noticing - if we stop to listen to birdsong or pause to watch their busy daily lives - we give ourselves a break from our own stresses.  

Get ad-free episodes to The Happiness Lab by subscribing to Pushkin+ on Apple Podcasts or Pushkin.fm. Pushkin+ subscribers can access ad-free episodes, full audiobooks, exclusive binges, and bonus content for all Pushkin shows. 

Subscribe on Apple: apple.co/pushkin
Subscribe on Pushkin: pushkin.fm/plus

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For the International Day of Happiness, we're sharing a special episode from The Happiness Lab. It's a chance to talk about happiness and what we can all do to be happier. March 20th also sees the release of the World Happiness Report. A big finding of 2025's report is that more of us are dining alone—and that's bad news. 

The report's editor Jan-Emmanuel De Neve shares the stark figures showing that shared meals are in decline, while Dr. Anne Fischel of The Family Dinner Project gives tips on how to dine better with friends, families and colleagues. 

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The holidays are supposed to be a time of joy. But all too often, the darker, colder days of winter, and even the stress of preparing for the holidays themselves, can lead people to feel something else: rushed, stressed, lonely, or even hopeless. How can you make sure this year is bright?

Dr Laurie joins Dave DeSteno on his show How God Works: The Science Behind Spirituality to unpack the psychological secrets of celebrations from Christmas, to Hanukkah, to Yule, and more. They’ll also discuss how we can put that wisdom into practice, whatever our beliefs, to make this season a happier and healthier one for all.

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How is 5G powering the use of AI to revolutionize life-saving solutions? Malcolm sits with T-Mobile for Business CMO Mo Katibeh, 3AM Innovations COO Ryan Litt, and the University of Miami Miller School of Medicine's Dr. Azizi Seixas to find out in this special episode of Revisionist History. Brought to you in partnership with T-Mobile for Business, and recorded live from the Mobile World Congress in Las Vegas.

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The biggest names in wellness podcasting - "The Titans of Happiness" - come together to talk about the greatest mental health challenges facing us in 2024 and the very simple things we can all do to be happier. 

Joining Dr Laurie Santos for this World Mental Health Day special are: 

Dr Joy Harden Bradford, the clinical psychologist and host of the podcast Therapy for Black Girls.

Gretchen Ruben, the best-selling author, host of Happier with Gretchen Rubin and all-round happiness guru at GretchenRubin.com.

Dan Harris, the former TV news anchor who now fronts 10% Happier with Dan Harris and the online community at Dan Harris.com. 

And since this is an extra special episode, Dr Laurie invited one extra special guest, Sesame Street’s Elmo. 

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It’s hard to stay hopeful these days. Stanford professor Jamil Zaki has been studying the incredible depth of human kindness for decades, but even he gives in to cynicism when he doubts our ability to be civil and cooperative. 

That’s a shame - because shedding cynicism and grasping hope will make you happier and healthier. Jamil and Dr Laurie Santos look at the scientific evidence showing that we should be more trusting of other people and optimistic about our facility to work together. 

Jamil's book Hope for Cynics: The Surprising Science of Human Goodness is out now.

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In the beautiful mountain town of Idyllwild, a wealthy widow named Dia Abrams suddenly vanishes from her home. She leaves behind her idyllic ranch, estranged children and a messy legal battle.

Two men in her life, her son and a man who claims to be her fiance, launch public campaigns to find her. But soon, their efforts – and stories – begin to unravel.

Enjoy this preview from Where's Dia? A new podcast from Pushkin Industries and iHeartPodcasts.

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