Sheena Josselyn and Paul Frankland’s paradigm-shifting work includes selectively erasing fear memories in mice and discovering what drives early childhood amnesia. We talk to the pair–who are partners in work and life–about taking on one of the brain’s big mysteries. (For behind-the-scenes extras and show notes or to fund research like this, please visit SickKidsFoundation.com/podcast.) Generously sponsored by CIBC and edited by Quill, this is the SickKids VS Podcast.

Faced with new symptom after new symptom, Daniel’s family grappled for years with an unknown disease. But blood tests and body scans couldn’t reveal the underlying problem. Join the quest for Daniel’s diagnosis, where scientific advances proved key to unlocking a treatment. (For behind-the-scenes extras and show notes or to fund research like this, please visit SickKidsFoundation.com/podcast.) Generously sponsored by CIBC and edited by Quill, this is the SickKids VS Podcast.

Early brain injury can cause unique behavioral problems for children and youth — and unique stresses and challenges for their caregivers. We introduce a pioneering program that offers practical tools and one-on-one coaching to caregivers at home. (For behind-the-scenes extras and show notes or to fund research like this, please visit SickKidsFoundation.com/podcast.) Generously sponsored by CIBC and edited by Quill, this is the SickKids VS Podcast.

When a child suffers a serious brain injury, doctors can help them cope with the consequences, but they often can’t fix the damage that has been done. Or can they? Spurred by patient families who won’t settle for the status quo, a team of scientists is challenging a long-held belief about the brain’s limits. (For behind-the-scenes extras and show notes or to fund research like this, please visit SickKidsFoundation.com/podcast.) Generously sponsored by CIBC and edited by Quill, this is the SickKids VS Podcast.

Parents of babies born with complex medical needs are at high risk of stress, anxiety, and depression. One doctor took notice. She reveals a new type of care that could help families across the country during a critical moment: the rocky return home from the hospital. (For behind-the-scenes extras and show notes or to fund research like this, please visit SickKidsFoundation.com/podcast.) Generously sponsored by CIBC and edited by Quill, this is the SickKids VS Podcast.

Most big breakthroughs start with a simple question. In the new season of SickKids VS, we take you behind the scenes of remarkable stories wherein each episode researchers ask questions like: Can we heal the brain? How should we talk to kids about dying? And what can doctors do when a child’s disease remains unknown—for years? Join us on the frontlines in the fight for child health. Season 3 starts May 4. Subscribe now.

In surgery, practice makes perfect. But for surgeons operating on tiny hearts with rare defects, that kind of experience can take decades. So, SickKids cardiac radiologist Dr. Shi-Joon Yoo devised a novel solution to speed things up: 3D-printed hearts. What began in a rented office has since blossomed into a fast-growing program, attracting surgeons from around the world to SickKids for expert-led, hands-on surgical training.For more information on this episode, visit sickkidsfoundation.com/podcast/surgicaltraining. And to fund research like this, go to sickkidsfoundation.com/donate SickKids Foundation is proud to recognize CIBC as the Premier Sponsor of the SickKids VS Podcast.

Baby Izaan was in trouble. Despite multiple rounds of chemotherapy, his tumour continued to grow, and time was running out. Izaan’s oncologist, Dr. David Malkin, enrolled him in KiCS: The SickKids Cancer Sequencing Program. The hope? That by analyzing the tumour’s DNA, they could figure out how to stop it.For more information on this episode, visit sickkidsfoundation.com/podcast/cancergenetics. And to fund research like this, go to sickkidsfoundation.com/donate.SickKids Foundation is proud to recognize CIBC as the Premier Sponsor of the SickKids VS Podcast.

Ryan is severely allergic to peanuts. Like, hives-blossoming, throat-closing, get-me-epinephrine-now kind of allergic. But as part of a clinical trial at SickKids, which could change the course of allergy treatment, he now eats a tiny dose of the stuff every night. That’s because peanuts—the very food that could kill him—might also be the key to protecting him.WARNING: Please do not try this without the close supervision of a doctor.For more information on this episode, visit sickkidsfoundation.com/podcast/foodallergy . And to fund research like this, go to sickkidsfoundation.com/donateSickKids Foundation is proud to recognize CIBC as the Premier Sponsor of the SickKids VS Podcast.

First, Gavriel’s muscles got weaker. Then, he lost the ability to walk. From there, things will only get worse. The cause is Duchenne Muscular Dystrophy, a genetic disorder with no cure. But that might soon change. Using CRISPR, a state-of-the-art gene-editing tool, SickKids scientists were able to correct the disease-causing mutation in mice. The result? Improved muscle strength and function—and no signs of paralysis. Now, they’re refining their approach, so they can take this treatment out of the lab and into the world.For more information on this episode, visit sickkidsfoundation.com/podcast/duchenne. And to fund research like this, go to sickkidsfoundation.com/donateSickKids Foundation is proud to recognize CIBC as the Premier Sponsor of the SickKids VS Podcast.