In today’s episode, William Mulligan sits down with neuroscientist and psychedelic researcher Manesh Girn to explore the intersection of Stoic philosophy and modern science. Manesh shares his perspective on core Stoic ideas such as virtue, the dichotomy of control, and amor fati, while drawing connections to the transformative potential of psychedelics.

The conversation dives into themes of neuroplasticity, the role of health in living virtuously, and how both Stoicism and psychedelics can help us overcome trauma, reframe our perceptions, and live more fully in the present.

From discussing Marcus Aurelius and Epictetus to the neuroscience of predictive coding and emotional breakthroughs, this episode offers a rich look at how ancient wisdom and contemporary research can complement each other in the pursuit of a good life.