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Pedro, Guilherme e João se reunem novamente com o dr. José Carlos para falar de infarto sem supradesnivelamento de segmento ST! Um tema com mudanças recentes e cheio de dúvidas! Qual o melhor antiplaquetário depois do AAS? Fazer na sala de emergência ou na hemodinâmica? E o restante da prescrição? Qual a melhor hora pra fazer o cateterismo? Isso e muito mais nesse episódio!

Referências:

1. COLLET, Jean-Philippe et al. 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: the Task Force for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). European heart journal, v. 42, n. 14, p. 1289-1367, 2021.

2. NICOLAU, José Carlos et al. Diretrizes da Sociedade Brasileira de Cardiologia sobre Angina Instável e Infarto Agudo do Miocárdio sem Supradesnível do Segmento ST–2021. Arquivos Brasileiros de Cardiologia, v. 117, p. 181-264, 2021.

3. SCHÜPKE, Stefanie et al. Ticagrelor or prasugrel in patients with acute coronary syndromes. New England Journal of Medicine, v. 381, n. 16, p. 1524-1534, 2019.

4. COMMIT (CLOPIDOGREL AND METOPROLOL IN MYOCARDIAL INFARCTION TRIAL) COLLABORATIVE GROUP et al. Early intravenous then oral metoprolol in 45 852 patients with acute myocardial infarction: randomised placebo-controlled trial. The Lancet, v. 366, n. 9497, p. 1622-1632, 2005.

5. KUBICA, Jacek et al. Morphine delays and attenuates ticagrelor exposure and action in patients with myocardial infarction: the randomized, double-blind, placebo-controlled IMPRESSION trial. European heart journal, v. 37, n. 3, p. 245-252, 2016.

6. HOBL, Eva-Luise et al. Morphine decreases clopidogrel concentrations and effects: a randomized, double-blind, placebo-controlled trial. Journal of the American College of Cardiology, v. 63, n. 7, p. 630-635, 2014.

7. MEINE, Trip J. et al. Association of intravenous morphine use and outcomes in acute coronary syndromes: results from the CRUSADE Quality Improvement Initiative. American heart journal, v. 149, n. 6, p. 1043-1049, 2005.

8. ANDERSON, H. Vernon et al. One-year results of the Thrombolysis in Myocardial Infarction (TIMI) IIIB clinical trial: a randomized comparison of tissue-type plasminogen activator versus placebo and early invasive versus early conservative strategies in unstable angina and non-Q wave myocardial infarction. Journal of the American College of Cardiology, v. 26, n. 7, p. 1643-1650, 1995.

9. ABUZAID, Ahmed et al. Oxygen therapy in patients with acute myocardial infarction: a systemic review and meta-analysis. The American journal of medicine, v. 131, n. 6, p. 693-701, 2018.