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Raphael e João recebem mais uma vez a Dra. Nathalie Santana, dessa vez para discutir o tratamento farmacológico da obesidade! Quais as indicações de tratamento farmacológico? Quais as opções on-label? Quais as diferenças de preço e potência das medicações? Isso e muito mais nesse episódio!

Referências:

1. Obesity in adults: Drug therapy Author:Leigh Perreault, MD Section Editor: F Xavier Pi-Sunyer, MD, MPH Deputy Editor: Lisa Kunins, MD

2. ABESO - Diretrizes brasileiras de Obesidade 2016

3. SCHUTZ, Dominique Durrer et al. European practical and patient-centred guidelines for adult obesity management in primary care. Obesity facts, v. 12, n. 1, p. 40-66, 2019.

4. VA/DoD Clinical Practice Guideline for the Management of Adult Overweight and Obesity

5. AMERICAN DIABETES ASSOCIATION et al. 2. Classification and diagnosis of diabetes: Standards of Medical Care in Diabetes—2021. Diabetes Care, v. 44, n. Supplement 1, p. S15-S33, 2021.

6. APOVIAN, Caroline M. et al. Pharmacological management of obesity: an Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, v. 100, n. 2, p. 342-362, 2015.

7. WILDING, John PH et al. Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 2021.

8. JAMES, W. Philip T. et al. Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. New England Journal of Medicine, v. 363, n. 10, p. 905-917, 2010.

9. JAMES, W. Philip T. et al. Effect of sibutramine on weight maintenance after weight loss: a randomised trial. The Lancet, v. 356, n. 9248, p. 2119-2125, 2000.

10. YEH, James S.; KUSHNER, Robert F.; SCHIFF, Gordon D. Obesity and management of weight loss. New England Journal of Medicine, v. 375, n. 12, p. 1187-1189, 2016.

11. KAHAN, Scott; MANSON, JoAnn E. Obesity treatment, beyond the guidelines: practical suggestions for clinical practice. Jama, v. 321, n. 14, p. 1349-1350, 2019.

12. MCALLISTER, Emily J. et al. Ten putative contributors to the obesity epidemic. Critical reviews in food science and nutrition, v. 49, n. 10, p. 868-913, 2009

13. GBD 2015 OBESITY COLLABORATORS. Health effects of overweight and obesity in 195 countries over 25 years. New England Journal of Medicine, v. 377, n. 1, p. 13-27, 2017.