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Joanne, Fred e Nathalie discutem sobre o diagnóstico de pré-diabetes, as diferenças em pacientes idosos e o tratamento com MEV e metformina. 

 Minutagem:

(00:00) Apresentação

(01:44) Diagnóstico de Pré-Diabetes

(02:43) Quais exames pedir para diagnóstico? 

(04:30) Porque tratar o pré-diabetes?

(06:04) Evolução do pré-diabetes em idosos

(07:20) Tratamento não farmacológico

(09:36) Tratamento farmacológico

(11:15) Comparação entre tratamento não farmacológico e farmacológico

(12:15) Possibilidade de interrupção da terapia medicamentosa

(13:13) Outros medicamentos

(14:40) Salves

(15:11) Encerramento Referências:

1. Cobas, Roberta, et al. "Diagnóstico do diabetes e rastreamento do diabetes tipo 2." Diretriz Oficial da Sociedade Brasileira de Diabetes (2022): 557753-2022. 2. Zhang, Xuanping, et al. "A1C level and future risk of diabetes: a systematic review." Diabetes care 33.7 (2010): 1665-1673.

3. Rooney, Mary R., et al. "Risk of progression to diabetes among older adults with prediabetes." JAMA internal medicine 181.4 (2021): 511-519. 4. Jesudason, David R., et al. "Macrovascular risk and diagnostic criteria for type 2 diabetes: implications for the use of FPG and HbA1c for cost-effective screening." Diabetes care 26.2 (2003): 485-490.

5. ElSayed, Nuha A., et al. "Summary of revisions: Standards of Care in Diabetes—2023." Diabetes Care 46.Supplement_1 (2023): S5-S9. 6. Knowler, William C., et al. "Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin." (2002): 393. 7. Hamman, Richard F., et al. "Effect of weight loss with lifestyle intervention on risk of diabetes." Diabetes care 29.9 (2006): 2102-2107.

8. Chiasson, Jean-Louis, et al. "Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial." The Lancet 359.9323 (2002): 2072-2077. 9. DeFronzo, Ralph A., et al. "Pioglitazone for diabetes prevention in impaired glucose tolerance." New England Journal of Medicine 364.12 (2011): 1104-1115. 10. Spence, J. David, et al. "Efficacy of lower doses of pioglitazone after stroke or transient ischaemic attack in patients with insulin resistance." Diabetes, Obesity and Metabolism 24.6 (2022): 1150-1158. 11. Torgerson, Jarl S., et al. "XENical in the Prevention of Diabetes in Obese Subjects (XENDOS) Study. A randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients." Clinical Diabetology 5.2 (2004): 95-104.

12. Le Roux, Carel W., et al. "3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial." The Lancet 389.10077 (2017): 1399-1409. 13. Pittas, Anastassios G., et al. "Vitamin D and risk for type 2 diabetes in people with prediabetes: a systematic review and meta-analysis of individual participant data from 3 randomized clinical trials." Annals of internal medicine 176.3 (2023): 355-363.