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PSA and DRE screening – to do or not to do, where is the evidence? And intensive lifestyle changes in early prostate cancer.
1. Digital rectal examination - recommendations
2. PSA test– what is it, the benefits and risks, medicare implications, the review of guidelines for screening for average to high risk and follow up, what to do with a + result, age related reference ranges and the PSA variables – free/total %, double, velocity, PHI, MRI
3. Intensive lifestyle change in early prostate cancer
References:
Prostate Cancer Foundation of Australia and Cancer Council Australia Expert Advisory Panel – Clinical practice guidelines PSA testing and early management of test detected prostate cancer PSA Testing 2015, http://wiki.cancer.org.au/australia/Guidelines:PSA_Testing
Urological Society of Australia and New Zealand April 2017 statement
http://www.racgp.org.au/your-practice/guidelines/prostate-cancer/
http://www.racgp.org.au/afp/2013/januaryfebruary/prostate-cancer/
https://www.ncbi.nlm.nih.gov/pubmed/16822843
Intensive lifestyle change in prostate cancer, 2005 - https://www.ncbi.nlm.nih.gov/pubmed/16094059
Gene expression changes in intensive lifestyle changes in prostate cancer, 2008 - https://www.ncbi.nlm.nih.gov/pubmed/18559852
https://www.cancer.org/cancer/prostate-cancer/detection-diagnosis-staging/how-diagnosed.html
http://www.snp.com.au/media/305331/item_44879_prostate_cancer_testing_november_2016.pdf
http://www.sapathology.sa.gov.au/wps/wcm/connect/sa+pathology+internet+content+new/content/news/what+is+psa
Today we will cover a case on weight with question and answers. Questions include:
Question 1 What further history do you want to obtain for weight loss?
Question 2 What examination do you want to perform?
Question 3 Are there any investigations to perform?
Question 4 How does this change your management when prescribing the pill?
Question 5 She asks you – "what about the low carb high fat diet?"
Question 6 How successful are lifestyle weight loss programs in the long run?
Question 7 What medication options are there and the indications and side effects?
Question 8 When would you refer for a bariatric surgical opinion?
Main references:
http://www.nejm.org/doi/full/10.1056/NEJMoa1614292?rss=searchAndBrowse&
https://www.urmc.rochester.edu/news/story/4217/commonly-prescribed-drug-for-lower-back-pain-not-effective.aspx
http://www.cochrane.org/CD012087/BACK_non-steroidal-anti-inflammatory-drugs-chronic-low-back-pain
NHMRC, Clinical Practice Guidelines for the Management of Overweight and Obesity in Adults, Adolescence and Children in Australia, Aus Gov, 2013, https://www.nhmrc.gov.au/_files_nhmrc/publications/attachments/n57_obesity_guidelines_140630.pdf
Effects of Low-Carbohydrate versus low fat diets on metabolic risk factors: Meta-analysis, 2012, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530364/
Grima et al, Obesity, RACGP AFP, 2013 http://www.racgp.org.au/afp/2013/august/obesity/
Hamdy et al, Obesity, Medscape, 2017 http://emedicine.medscape.com/article/123702-clinical
Bray et al, Obesity in Adults, UpToDate, 2017
UKMEC criteria, 2016, http://www.fsrh.org/standards-and-guidance/documents/ukmec-2016/
Today we will cover a case on weight with question and answers. Questions include:
Question 1 What further history do you want to obtain for weight loss?
Question 2 What examination do you want to perform?
Question 3 Are there any investigations to perform?
Question 4 How does this change your management when prescribing the pill?
Question 5 She asks you – “what about the low carb high fat diet?”
Question 6 How successful are lifestyle weight loss programs in the long run?
Question 7 What medication options are there and the indications and side effects?
Question 8 When would you refer for a bariatric surgical opinion?
Main references:
http://www.nejm.org/doi/full/10.1056/NEJMoa1614292?rss=searchAndBrowse&
https://www.urmc.rochester.edu/news/story/4217/commonly-prescribed-drug-for-lower-back-pain-not-effective.aspx
http://www.cochrane.org/CD012087/BACK_non-steroidal-anti-inflammatory-drugs-chronic-low-back-pain
NHMRC, Clinical Practice Guidelines for the Management of Overweight and Obesity in Adults, Adolescence and Children in Australia, Aus Gov, 2013, https://www.nhmrc.gov.au/_files_nhmrc/publications/attachments/n57_obesity_guidelines_140630.pdf
Effects of Low-Carbohydrate versus low fat diets on metabolic risk factors: Meta-analysis, 2012, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530364/
Grima et al, Obesity, RACGP AFP, 2013 http://www.racgp.org.au/afp/2013/august/obesity/
Hamdy et al, Obesity, Medscape, 2017 http://emedicine.medscape.com/article/123702-clinical
Bray et al, Obesity in Adults, UpToDate, 2017
UKMEC criteria, 2016, http://www.fsrh.org/standards-and-guidance/documents/ukmec-2016/
Annals of Internal Medicine, Noninvasive treatments for Acute, Subacute, and Chronic Back Pain, 2017, http://annals.org/aim/article/2603228/noninvasive-treatments-acute-subacute-chronic-low-back-pain-clinical-practice
National Institute for health and care Excellence (2016). Low back pain and sciatica in over 16s: assessment and management. NICE guideline [NG59]. Retrieved from https://www.nice.org.uk/guidance/ng59
http://clinicalevidence.bmj.com/x/systematic-review/1116/overview.html
http://www.racgp.org.au/your-practice/guidelines/handi/interventions/musculoskeletal/mindfulness-and-cbt-for-chronic-low-back-pain/
http://www.racgp.org.au/your-practice/guidelines/handi/interventions/musculoskeletal/exercise-for-chronic-low-back-pain/
Deyo RA. Real help and red herrings in spinal imaging. N Engl J Med, 2013
https://www.mja.com.au/journal/2011/195/8/back-pain-and-leg-weakness
http://www.bmj.com/content/347/bmj.f7095http://www.imagingpathways.health.wa.gov.au/radiation/pages/jop_principles.html
https://www.keele.ac.uk/sbst/
http://www.cochrane.org/CD001351/BACK_acupuncture-and-dry-needling-for-low-back-pain
http://www.cochrane.org/CD004059/BACK_prolotherapy-injections-for-chronic-low-back-pain
Bardin, L D, King P, Maher C G. (2017). Diagnostic triage for low back pain: a practical approach for primary care MJA 206 (6) 3 April. O'Sullivan P., Lin I.B. (2014). Acute low back pain. Beyond drug therapies. Pain Management Today; 1(1): 8-13. 15. NSW Agency for Clinical Innovation (2016). Management of people with acute low back pain: model of care. Chatswood; NSW Health. Retrieved from https://www.aci.health.nsw.gov.au/__data/assets/pdf_file/0007/336688/acute-low-back-pain-moc.pdfAnnals of Internal Medicine, Noninvasive treatments for Acute, Subacute, and Chronic Back Pain, 2017, http://annals.org/aim/article/2603228/noninvasive-treatments-acute-subacute-chronic-low-back-pain-clinical-practice
National Institute for health and care Excellence (2016). Low back pain and sciatica in over 16s: assessment and management. NICE guideline [NG59]. Retrieved from https://www.nice.org.uk/guidance/ng59
http://clinicalevidence.bmj.com/x/systematic-review/1116/overview.html
http://www.racgp.org.au/your-practice/guidelines/handi/interventions/musculoskeletal/mindfulness-and-cbt-for-chronic-low-back-pain/
http://www.racgp.org.au/your-practice/guidelines/handi/interventions/musculoskeletal/exercise-for-chronic-low-back-pain/
Deyo RA. Real help and red herrings in spinal imaging. N Engl J Med, 2013
https://www.mja.com.au/journal/2011/195/8/back-pain-and-leg-weakness
http://www.bmj.com/content/347/bmj.f7095http://www.imagingpathways.health.wa.gov.au/radiation/pages/jop_principles.html
https://www.keele.ac.uk/sbst/
http://www.cochrane.org/CD001351/BACK_acupuncture-and-dry-needling-for-low-back-pain
http://www.cochrane.org/CD004059/BACK_prolotherapy-injections-for-chronic-low-back-pain
Bardin, L D, King P, Maher C G. (2017). Diagnostic triage for low back pain: a practical approach for primary care MJA 206 (6) 3 April. O'Sullivan P., Lin I.B. (2014). Acute low back pain. Beyond drug therapies. Pain Management Today; 1(1): 8-13. 15. NSW Agency for Clinical Innovation (2016). Management of people with acute low back pain: model of care. Chatswood; NSW Health. Retrieved from https://www.aci.health.nsw.gov.au/__data/assets/pdf_file/0007/336688/acute-low-back-pain-moc.pdfFrom the publisher's feed

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