Endo Battery

The Gut-Brain Connection: Sorting Endometriosis from IBS, POTS, and MCAS With Dr. Zac Spiritos


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A deep dive into the tangled web of GI symptoms and how they connect to endometriosis, EDS, POTS, and Mast Cell Activation Syndrome. Dr. Zac Spiritos, a neuro-gastroenterologist, shares insights on differentiating between these conditions and finding effective treatment approaches.

• IBS is a "software not hardware problem" involving miscommunication between gut and brain nerves
• Endometriosis can sensitize nerves in the pelvis, leading to IBS-like symptoms even after excision
• POTS affects the autonomic nervous system, causing standing tachycardia and various GI symptoms
• Mast Cell Activation Syndrome manifests through skin issues and unusual GI symptoms like early-onset heartburn
• EDS affects connective tissue throughout the body, potentially causing problems in every part of the GI tract
• Salt intake helps POTS patients by increasing blood volume, though this approach isn't sustainable for everyone
• Finding a doctor who remains curious about complex conditions is crucial for proper diagnosis and treatment
• Patient education is essential for informed decision-making and long-term management of chronic conditions


Follow Dr. Zac Spiritos on Instagram @drzacspiritos


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