SHE MD

Longevity physician Dr. Darshan Shah joins SheMD for a wide-ranging conversation about how women can become more proactive about their health and focus on extending healthspan, not simply lifespan.

Dr. Shah explains the biomarkers he follows with patients, including markers related to metabolic health, cardiovascular risk, inflammation and hormones, and why he believes identifying changes early can help people intervene before chronic disease develops.

We also take a deeper look at women’s cognitive health, including the tests and risk factors Dr. Shah considers when evaluating brain health and how exercise, sleep, metabolic health and cardiovascular health may all play a role.

Then we get practical. Dr. Shah shares the foundational habits he prioritizes for longevity, including strength training, VO2 max training, sleep, nutrition and reducing environmental exposures.

Plus, we discuss some of the most talked-about interventions in longevity medicine, including creatine, sauna, cold plunges, NAD, peptides, stem cells, red light therapy, hyperbaric oxygen and plasma exchange.

Dr. Shah also explains why women should be cautious about unregulated peptides and why advanced therapies should come after the fundamentals, not replace them.

His biggest recommendation? Build muscle. Dr. Shah says lifting heavy weights consistently is one of the most powerful longevity tools women already have access to.

Sponsors

Talkiatry: Featured in a sponsored segment highlighting its virtual psychiatry services and access to mental health care.

Babbel: Featured in a sponsored segment promoting its language-learning platform and tools for building language skills.

OSEA Malibu: Featured in a sponsored segment highlighting its skincare and body-care products.

Arca Wealth: Featured in a sponsored segment discussing financial planning and wealth management services.

Gusto: Featured in a sponsored segment highlighting its platform for simplifying payroll, tax filings, HR, and employee benefits.

What You’ll Learn

• What longevity really means and why extending your health span is just as important as extending your lifespan.
• Why preventative medicine starts with understanding your individual biology through blood work, physical assessments, cognitive testing, and personalized health data.
• The key biomarkers women should consider tracking, including hemoglobin A1C, fasting insulin, ApoB, high-sensitivity C-reactive protein, and important hormones.
• How metabolic dysfunction, cardiovascular risk, inflammation, and hormonal changes can influence long-term health.
• Why gut health plays an important role in immune function and inflammation, and how fiber, fermented foods, and a healthy microbiome support gut health.
• What leaky gut means, how gut health is evaluated, and why reducing ultra-processed foods and excess sugar may help support the microbiome.
• How environmental toxins, mold, heavy metals, pesticides, and endocrine-disrupting chemicals are evaluated through specialized testing.
• Why genetic screening can help identify certain health risks, including cardiovascular disease and Alzheimer's, and what the APOE4 gene may indicate.
• How menopause, declining estrogen, inflammation, and metabolic health intersect with women's cognitive health and Alzheimer's risk.
• Which emerging blood biomarkers, including p-tau 217 and the amyloid ratio, are being used to assess potential Alzheimer's-related changes.
• How cognitive testing, EEG assessments, and brain blood-flow measurements can help evaluate memory, executive function, and cognitive performance.
• Why cardiovascular and metabolic health are important considerations when developing a plan to protect long-term brain health.
• How VO2 max training, strength training, and other forms of exercise may support cardiovascular function and cognitive health.
• Why sleep quality matters for brain health, including the importance of deep sleep and establishing a consistent sleep routine.
• How chronic stress and elevated cortisol may affect inflammation, metabolism, and overall health, and why incorporating more restorative practices matters.
• Practical ways to reduce environmental toxin exposure through air purification, water filtration, food choices, and personal care products.
• What to know about sauna use and cold plunges, including the differences in available research and their potential benefits.
• The research behind creatine, including its potential role in muscle strength, muscle mass, and cognitive performance.
• What NAD is, how it relates to cellular energy production, and what researchers still need to understand about NAD supplementation.
• What peptides are, how they function as biological signals, and the differences between established peptide medications and less-studied treatments.
• What to consider before pursuing peptides, including sourcing, safety data, FDA approval, and potential concerns for people with a history of cancer.
• What the current research suggests about stem cell treatments, including the importance of proper manufacturing, handling, and clinical oversight.
• How red light therapy may influence circulation and collagen production, and why device wavelength matters.
• Which foundational supplements Dr. Shaw discusses, including vitamin D3 with K2, magnesium, omega-3s, creatine, and methylated B vitamins.
• Why intermittent fasting may not be appropriate for everyone, particularly when it leads to inadequate protein intake or increased stress.
• Why heavy resistance training at least three times a week is one of the most important habits women can prioritize for healthy aging.
• Why estrogen and ApoB are two important numbers women should understand when evaluating their long-term health.

Key Timestamps

00:00 The most powerful longevity tool women aren't using

02:42 How preventative medicine starts with personalized biomarkers

03:49 The key health markers every woman should know

04:47 Understanding metabolic health, A1C, and fasting insulin

06:51 Why estrogen, progesterone, testosterone, thyroid, and cortisol matter

07:15 The connection between gut health and chronic inflammation

08:01 Leaky gut, the microbiome, and immune health

09:36 How fiber and fermented foods support gut health

10:32 Choosing probiotics and evaluating supplement quality

12:22 Testing for environmental toxins and genetic health risks

14:45 Dr. Shaw's personal experience reversing chronic health conditions

18:16 Why women's cognitive health deserves more attention

20:37 Understanding women's risk for Alzheimer's disease

23:27 Measuring blood flow to the brain

26:19 VO2 max training and improving microvascular health

28:54 The foundational lifestyle habits that support longevity

29:24 Nutrition, exercise, and strength training for brain health

31:39 Improving sleep quality and evaluating sleep medications

33:05 Why keeping electronics out of the bedroom matters

38:11 How to reduce everyday exposure to environmental toxins

40:12 Ultra-processed foods and environmental chemicals

40:56 Personal care products and everyday toxin exposure

42:40 Advanced treatments for supporting brain health

43:08 Transcranial magnetic stimulation and mental health

43:38 The connection between depression, anxiety, and cognitive health

44:58 Plasma exchange and emerging longevity research

47:02 Sauna, cold plunges, and hot-cold contrast therapy

47:27 What the research says about sauna use

48:14 Cold plunges, inflammation, and nervous system regulation

49:41 Creatine for muscle strength and cognitive health

53:01 What are peptides and how do they work?

56:00 Peptide safety, sourcing, and regulatory considerations

59:05 Healing, and inflammation

1:00:21 Why people with a history of cancer should be especially cautious with unproven treatments

1:03:52 Stem cell treatments and what the research currently shows

1:06:19 Red light therapy, circulation, and collagen production

1:07:32 How chronic stress and cortisol affect longevity

1:09:49 Breathwork, recovery, and tracking heart rate variability

1:11:51 The most powerful longevity tool for women: heavy strength training

1:13:02 The future of preventative medicine and longevity

1:14:54 Dr. Shaw's final thoughts on preventative healthcare

Key Takeaways

• Longevity is about health span, not just lifespan. Dr. Shaw emphasizes that the goal is to maintain physical strength, cognitive function, and quality of life for as long as possible. Preventative care focuses on identifying potential health risks before they develop into chronic disease.
• Knowing your biomarkers can change the way you approach your health. Blood sugar, fasting insulin, ApoB, inflammation markers, and hormones can provide valuable insight into metabolic, cardiovascular, and hormonal health. Dr. Shaw encourages women to become more familiar with these numbers and discuss appropriate testing with their healthcare providers.
• Metabolic health and inflammation are connected to long-term health. The conversation highlights the relationship between blood sugar regulation, insulin, cardiovascular risk, and chronic inflammation. Gut health, nutrition, movement, and sleep are all important considerations when developing a preventative health plan.
• Your gut microbiome plays an important role in overall health. Fiber and fermented foods help support beneficial gut bacteria, while diets high in ultra-processed foods and added sugars may negatively affect the microbiome. Dr. Shaw also discusses the importance of evaluating supplement quality rather than automatically adding probiotics to your routine.
• Women's cognitive health deserves more attention. The discussion explores how estrogen, metabolic dysfunction, inflammation, and environmental exposures may intersect with cognitive health and Alzheimer's risk. Dr. Shaw explains how genetic screening, emerging blood biomarkers, and cognitive assessments can help provide additional information about brain health.
• Estrogen is an important consideration throughout the aging process. Dr. Shaw discusses estrogen's relationship with brain, bone, cardiovascular, and muscular health. Hormone therapy decisions should be individualized, particularly for women with a history of breast cancer or other conditions that may affect treatment eligibility.
• Strength training is one of the most important habits for healthy aging. Dr. Shaw recommends resistance training at least three times per week, emphasizing challenging weights and progressively building strength. Muscle supports metabolic health and produces signaling molecules called myokines that are also being studied for their role in brain health.
• VO2 max training and cardiovascular fitness matter. High-intensity interval training, regular movement, and strength training can support cardiovascular function and overall physical resilience. Dr. Shaw also discusses the relationship between blood flow and cognitive health.
• Sleep is essential for brain health. The conversation highlights the importance of sleep quality, particularly deep sleep, and establishing consistent routines. Monitoring sleep patterns can help identify areas for improvement, while medication decisions should be made with a healthcare provider.
• Reducing everyday toxin exposure doesn't have to be overwhelming. Dr. Shaw introduces an 80/20 approach focused on practical changes, such as improving indoor air quality, filtering drinking water, limiting ultra-processed foods, and evaluating personal care products.
• Not every popular longevity treatment has the same level of scientific evidence. Sauna use, cold plunges, NAD, peptides, stem cells, and red light therapy are all discussed, but the strength of available research varies. Dr. Shaw emphasizes understanding potential benefits, limitations, sourcing, and safety before pursuing emerging treatments.
• Creatine is worth understanding beyond muscle health. Dr. Shaw discusses research on creatine's potential benefits for muscle strength and cognitive performance, particularly in relation to aging and sleep deprivation. Supplementation should be considered in the context of individual health needs.
• More supplements and more fasting aren't necessarily better. Dr. Shaw identifies vitamin D3 with K2, magnesium, omega-3s, creatine, and methylated B vitamins as foundational supplements he discusses with patients. He also cautions that intermittent fasting may work against some women if it compromises protein intake or increases stress.
• Stress management is part of preventative healthcare. Chronic stress and sustained cortisol activation are discussed in relation to inflammation and metabolic health. Taking breaks, practicing breathwork, spending time outdoors, and monitoring recovery can help support a healthier balance between stress and relaxation.
• Personalized medicine requires tracking progress. Rather than relying solely on how you feel, Dr. Shaw encourages using appropriate biomarkers and physical or cognitive assessments to evaluate whether a treatment or lifestyle change is actually making a difference.
• Prevention starts before symptoms appear. One of the central messages of the conversation is that women should not wait until they develop a chronic condition to start prioritizing their health. Understanding personal risk factors and building sustainable habits can make a meaningful difference over time.

Guest Bio - Dr. Daron Shaw

Dr. Darshan Shah is a board-certified surgeon, longevity medicine specialist, and founder and CEO of Next Health, a health optimization and longevity clinic focused on preventive medicine and personalized healthcare. After earning his medical degree at just 21 years old and completing surgical training at the Mayo Clinic, Dr. Shah transitioned from traditional surgery to a proactive approach centered on disease prevention, biomarker testing, metabolic health, and extending healthspan. He is also the host of the EXTEND Podcast, where he explores the latest research and strategies for living a longer, healthier life.

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Why is your hair suddenly thinning, shedding or breaking?

Board-certified dermatologist and Chief Medical Advisor at Nutrafol, Dr. Heather Woolery-Lloyd, joins Dr. Thaïs Aliabadi and Mary Alice Haney for a deep dive into the many different reasons women experience hair thinning and why figuring out the cause matters before choosing an approach that’s right for them.

We break down everything from stress-related shedding and postpartum hair thinning, perimenopause and menopause to nutritional gaps, tight hairstyles, extensions, heat and chemical damage.

Dr. Woolery-Lloyd also explains why hair shedding may not show up until 3 to 6 months after a stressful event and why something that happened months ago, including surgery, childbirth, a major move, divorce or rapid weight loss, may be connected to what you are seeing in the shower today.

We also discuss hair thinning associated with GLP-1 medications and why rapid or significant weight loss, reduced protein intake, and nutritional deficiencies may be more important factors than the medication itself.

Plus, we get into minoxidil, spironolactone, PRP, light therapy, hair supplements, protein, iron, vitamin D and what actually deserves a place in a hair growth plan.

If your part is getting wider, your ponytail feels thinner, or your shower drain suddenly is seeing more of a build up of hair , this episode will help you understand where to start. #NutrafolPartner

This episode is brought to you by Nutrafol. Let your hair be one less thing to worry about. See visibly thicker, stronger, faster growing hair in 3–6 months with Nutrafol Hair Growth Nutraceuticals.

For a limited time, Nutrafol is offering our listeners $10 off your first month’s subscription and free shipping when you visit Nutrafol dot com and enter promo code SHEMD.

Sponsors

IT Cosmetics and Smile Set are featured in sponsored advertising segments during this episode.

What You’ll Learn

• Why hair thinning and shedding can occur at different stages of a woman's life, including postpartum, perimenopause, and menopause.
• How estrogen fluctuations affect the hair growth cycle and why hormonal changes can contribute to shedding, thinning, and breakage.
• Why stress, surgery, childbirth, and other major life events can trigger hair shedding three to six months later.
• The difference between telogen effluvium, female pattern hair loss, and hair breakage, including the signs that may help distinguish them.
• How PCOS, insulin resistance, and androgen levels can contribute to hair thinning, acne, and unwanted facial or body hair.
• What current evidence suggests about hair shedding during GLP-1 treatment, including the potential roles of rapid weight loss, inadequate protein intake, and nutritional deficiencies.
• Why thyroid conditions, iron deficiency, low vitamin D, autoimmune disorders, and certain medications may contribute to hair loss.
• How tight ponytails, braids, extensions, heat styling, chemical treatments, and environmental exposure can damage hair or contribute to thinning.
• How dermatologists evaluate hair loss through medical history, physical examination, hair-pull testing, blood work, and, when needed, a scalp biopsy.
• Which treatment options may be considered for different types of hair loss, including minoxidil, anti-inflammatory treatments, light therapy, and PRP.
• What to look for when choosing a hair supplement, including clinical testing of the finished product, ingredient quality, and independent safety certifications.
• How protein intake, a balanced diet, and attention to nutritional deficiencies can support hair health.
• Why hair treatments require patience, with reduced shedding potentially taking months to appear and significant regrowth often taking six months or longer.
• Practical ways to reduce breakage, including choosing gentler hairstyles, minimizing tugging and pulling, and adjusting hair care to your hair type.
• Five key takeaways for women experiencing hair changes: seek care early, consider recent stressors, prioritize nutrition, evaluate appropriate supplementation, and give yourself grace.

Key Timestamps

00:00 Why your hair may be thinning months after a stressful event

01:20 How pregnancy, postpartum changes, and menopause affect hair health

03:51 Understanding the hair growth cycle

04:45 Why hair texture and breakage can change with age

05:50 How much daily hair shedding is normal?

07:47 Telogen effluvium and stress-related hair loss

10:10 Female pattern hair loss and a widening part

12:40 Understanding postpartum shedding and recovery

14:14 Hair thinning and breakage during perimenopause and menopause

15:28 How PCOS and insulin resistance affect hair health

17:21 GLP-1 medications, rapid weight loss, and hair shedding

19:53 Protein, iron, vitamin D, and other nutritional considerations

21:44 Thyroid disease and hair thinning

22:21 How tight hairstyles can cause traction alopecia

24:21 Autoimmune hair loss and alopecia areata

28:14 How heat, chemicals, and styling contribute to breakage

30:13 Why chemotherapy can cause hair loss

32:18 How dermatologists evaluate hair thinning and shedding

35:42 Medications that may contribute to hair loss

36:31 Treatment options for different types of hair loss

40:28 PRP injections and hair regrowth

42:14 What to look for in a science-backed hair supplement

44:33 Ingredients to consider in hair supplements

45:23 Hair care myths: Washing, brushing, and cutting your hair

47:28 When to start treatment and how long regrowth takes

48:09 Common hair growth myths and whether hats cause hair loss

48:59 Dr. Heather's five takeaways for healthier hair

Key Takeaways

• Hair loss has many different causes. Stress-related shedding, hormonal changes, PCOS, nutritional deficiencies, thyroid disease, autoimmune conditions, and mechanical or chemical damage can all affect hair. Identifying the underlying cause is essential because treatments vary depending on the type of hair loss.
• Hair shedding can appear months after a stressful event. Telogen effluvium occurs when a greater proportion of hair follicles shifts out of the active growth phase and into the resting phase. Shedding may become noticeable three to six months after childbirth, surgery, illness, or significant emotional stress.
• Hormonal changes can affect both hair growth and hair quality. Estrogen supports the active growth phase of hair, while declining estrogen during perimenopause and menopause can contribute to thinning in susceptible women. Hair can also become drier, more fragile, and more prone to breakage with age.
• GLP-1-associated hair shedding may be related to weight loss and nutrition. The discussion highlights rapid or significant weight loss, inadequate protein intake, and micronutrient deficiencies as potential contributors. Anyone experiencing hair loss while taking a GLP-1 medication should consult their healthcare provider rather than stopping or changing treatment independently.
• Tight hairstyles can cause preventable hair loss. Repeated tension from tight ponytails, braids, extensions, and other styling practices can lead to traction alopecia, often affecting the frontal hairline. Reducing tension early may help prevent lasting damage.
• Hair breakage and hair shedding are not the same. Shedding involves hairs leaving the growth cycle, while breakage occurs when the hair shaft becomes damaged. Heat, chemical treatments, UV exposure, and excessive pulling or manipulation can weaken hair and increase breakage.
• A thorough evaluation can help uncover underlying conditions. A dermatologist may review recent stressors, family history, menstrual patterns, medications, and hair care practices, along with examining the scalp. Depending on the individual, testing may include thyroid function, blood counts, iron and ferritin, vitamin D, and other targeted laboratory tests.
• Treatment should be tailored to the cause. Depending on the diagnosis, options may include topical or oral minoxidil, anti-inflammatory treatments, light therapy, PRP, nutritional support, or other prescription therapies. Not every treatment is appropriate for every person, so individualized medical guidance matters.
• Choose supplements based on evidence and safety. Dr. Heather recommends looking for clinical studies on the finished product rather than relying on individual ingredients alone. Independent quality and safety certifications can also help consumers evaluate supplement standards.
• Hair regrowth takes time. Reduced shedding may take around three months to become noticeable, while significant regrowth can take six months or longer. Products promising dramatic results within just a few weeks should be approached with skepticism.
• A balanced diet supports healthy hair. Adequate protein, fruits, vegetables, and sufficient vitamins and minerals are important considerations. Addressing a confirmed deficiency may be part of a broader treatment plan, but there is no single food or supplement that works for every cause of hair loss.
• Seek help early and give yourself grace. A widening part, a noticeably thinner ponytail, bald patches, or persistent changes in shedding are worth discussing with a healthcare professional. Early evaluation can help identify treatable causes, and hair changes should be approached with patience rather than self-blame.

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Dr. Mindy Pelz joins SheMD for a wide-ranging conversation about fasting, hormones and metabolic health throughout a woman’s life.

Mindy explains how her approach to fasting changed after she began seeing women experience symptoms including hair loss, thyroid issues and stalled weight loss when they fasted continuously without taking their menstrual cycle into account.

She breaks down how she approaches fasting during different phases of the cycle, why she recommends easing up on fasting before a period, and how those recommendations may change during perimenopause and after menopause.

Dr. Thaïs Aliabadi and Mindy also discuss insulin resistance, PCOS, metabolic health, ketones, protein, carbohydrates and the relationship between blood sugar and hormonal symptoms.

Mindy explains what she means by “metabolic switching,” how she structures an eating window, why she discourages constant snacking and what she likes women to eat when breaking a fast.

Plus, she shares why she sees menopause not as a decline but as an opportunity for women to rethink their health, their brains and the next chapter of their lives.

Sponsors

Prolon: Featured in an advertisement discussing its five-day program, which is described as supporting fat-focused weight loss while protecting lean muscle. The episode includes an offer of 15% off sitewide, plus a $40 bonus gift with a five-day program subscription, at prolonlife.com/gmd.

Huel: Featured in an advertisement for Huel Black Edition powder and ready-to-drink meals, highlighting protein, convenience, and nutritional content. The ad mentions 15% off online for new customers with code CMD at huel.com/gmd.

Peloton: Featured in an advertisement for the Peloton Tread Flex treadmill, highlighting its foldable design and at-home running, walking, hiking, and training options.

Sequencing.com: Featured in an advertisement for whole-genome testing, including information about genetic screening and medication-response insights. The ad mentions up to 10% off a full genome test, plus free shipping, with code GMD at sequencing.com.

IT Cosmetics: Featured in an advertisement for the Do-It All Sheer Tint Face Balm, highlighting its skincare ingredients and tinted coverage.

What You’ll Learn

• How Dr. Mindy Pelz's experience with chronic fatigue influenced her interest in nutrition, lifestyle changes, and women's health.
• Why she developed a cycle-based approach to fasting and what she observed when women adjusted their fasting routines around their menstrual cycles.
• How estrogen and progesterone differ in their metabolic roles, including why progesterone is associated with an increased need for glucose.
• Why the week before menstruation may call for changes to fasting and carbohydrate intake.
• How fasting strategies may differ for women who are menstruating, perimenopausal, or postmenopausal.
• What metabolic switching means, how the body uses glucose and ketones for energy, and how fasting relates to this process.
• How insulin resistance may contribute to metabolic changes associated with PCOS, including weight gain, acne, hair loss, and irregular periods.
• Why Dr. Mindy emphasizes metabolic health when discussing hormonal symptoms, brain fog, and changes in weight.
• What autophagy is and how Dr. Mindy describes its role in cellular maintenance and repair.
• Why food quality, adequate protein, healthy fats, fiber, and less frequent snacking are central to her approach to metabolic health.
• How to think about fasting duration and timing in relation to menstrual cycles and symptoms such as spotting, anxiety, and insomnia.
• Why Dr. Mindy describes menopause as an opportunity for reinvention, personal growth, and a new stage of leadership.
• How changes in estrogen may affect neurotransmitters involved in mood, motivation, memory, and emotional well-being.
• How novelty, storytelling, and exposure to natural daylight can support habits associated with cognitive health.
• What Dr. Mindy recommends considering when breaking a fast, including broth, fiber, protein, and olive oil.
• Why she believes lifestyle education should be a more central part of conversations about women's hormonal health.

Key Timestamps

00:00 Why fasting differently may change women's experiences

03:13 How lifestyle changes inspired her work in women's health

04:40 Why fasting needs to account for women's hormonal cycles

05:05 Autophagy and the origins of Dr. Mindy's fasting approach

06:30 How the menstrual cycle influenced her approach to fasting

08:24 Why fasting strategies may change during perimenopause and menopause

10:10 Fasting, cortisol, and changing needs during perimenopause

12:58 Insulin resistance, PCOS, and hormonal symptoms

14:53 Why weight changes in midlife aren't simply a matter of willpower

21:22 Why some women feel better fasting than others

23:40 The connection between metabolic health, mood, and PCOS symptoms

25:24 How long should women fast?

28:42 Why the week before your period may require a different approach

30:26 Fasting strategies after menopause

31:18 What metabolic switching means

31:44 Minerals and supplements during fasting

32:36 Dr. Mindy's fasting cycle explained

40:23 Hemoglobin A1C, food quality, and hormone-supportive foods

42:35 Why constant snacking may affect metabolic health

45:04 Why Dr. Mindy describes menopause as an upgrade

48:49 How menopause may influence the brain, people-pleasing, and leadership

51:17 Metabolic switching and brain health in midlife

52:40 Supporting mood and cognition as estrogen declines

54:29 Storytelling, memory, and cognitive health

56:04 The best foods to break a fast

58:08 Foods Dr. Mindy avoids and her perspective on hormonal freedom

59:14 The one thing Dr. Mindy wants every doctor to understand about women's health

59:41 Where to find Dr. Mindy's work

Key Takeaways

• Fasting should not be approached as a one-size-fits-all practice. Dr. Mindy emphasizes that women's metabolic and hormonal needs can change throughout the menstrual cycle and during perimenopause and postmenopause. She advocates adjusting fasting routines rather than assuming longer fasts are always better.
• The week before your period may require a different approach. Dr. Mindy explains that progesterone rises during the luteal phase and that she believes this phase calls for greater attention to glucose availability. She recommends a less restrictive approach to fasting during this time.
• Metabolic health is an important part of the hormonal health conversation. The discussion explores how insulin resistance may be associated with PCOS, changes in weight, and symptoms such as acne, hair loss, and brain fog. The guests emphasize looking beyond individual symptoms to consider broader health factors.
• Perimenopause calls for flexibility and symptom awareness. Because cycles can become irregular during the transition to menopause, Dr. Mindy suggests paying attention to changes such as spotting, anxiety, and insomnia when considering fasting. Individual needs and medical guidance are important.
• Food quality comes before extending a fasting window. Dr. Mindy recommends prioritizing minimally processed foods, protein, healthy fats, fiber, and nutrient-rich carbohydrate sources as part of her approach to metabolic health.
• Metabolic switching describes the body's use of different energy sources. Dr. Mindy discusses the shift between using glucose from food and producing ketones when food intake is reduced. She connects this process to her broader approach to fasting and metabolic health, while acknowledging that individual responses vary.
• Menopause can be a new beginning, not simply a decline. Drawing on the grandmother hypothesis and research discussed in the episode, Dr. Mindy presents postmenopause as a potential opportunity to embrace new priorities, personal growth, and leadership rather than viewing aging solely through a lens of loss.
• Brain health deserves attention during the menopausal transition. The conversation explores how estrogen changes may affect brain function and neurotransmitters involved in mood, motivation, and memory. Dr. Mindy highlights novelty, storytelling, and daylight exposure as lifestyle practices worth considering.
• Breaking a fast is an opportunity to prioritize nourishment. Dr. Mindy discusses broth, fiber-rich foods, protein, and olive oil as options she favors when returning to eating, emphasizing nutrient-dense meals rather than restrictive food rules.
• Lifestyle education should be central to women's healthcare. Dr. Mindy closes by emphasizing the importance of helping women understand their bodies, make informed lifestyle choices, and seek care that considers the broader context of their hormonal and metabolic health.

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For Breast Cancer Awareness Month, Dr. Thaïs Aliabadi shares her own breast cancer story and the lessons she wants every woman to take from it.

Dr. A explains how an abnormal breast biopsy led her to calculate her lifetime breast cancer risk, why she continued pushing for a preventative double mastectomy despite being repeatedly reassured that she was fine, and the shocking pathology result that revealed breast cancer after surgery.

She also breaks down six breast changes women should take seriously, including new or persistent breast lumps, skin dimpling, nipple changes, discharge, persistent flaky or scaly skin and changes in the appearance of the breast skin.

Dr. A explains the difference between traditional monthly self-exams and breast awareness, why knowing what is normal for your body matters, and when a breast change should prompt a call to your doctor.

Plus, we discuss dense breasts, mammograms and ultrasounds, family history, lifetime breast cancer risk, genetic testing, polygenic risk scores and why being young or having no family history does not mean a breast change should be dismissed.

This episode is about knowing your risk, noticing changes and becoming your own health advocate.

Sponsors

OSEA Malibu: The episode features OSEA Malibu’s Undaria Algae Body Oil, a seaweed-infused body oil designed to moisturize skin and promote a healthy-looking glow. Use code CMD for 10% off your first order.

Gusto: Featured in a sponsored segment about simplifying payroll, tax filings, HR, and employee benefits for small businesses. The episode promotes three months of free payroll for eligible new customers.

Peloton: Featured in a sponsored segment introducing the Tread Flex treadmill and discussing accessible running, walking, hiking, and at-home fitness.

David Protein: Featured in a sponsored segment highlighting the brand's high-protein bars, including its Gold and Bronze product lines. The episode promotes a buy-four-cartons-get-the-fifth-free offer.

What You’ll Learn

• How Dr. Thaïs Aliabadi discovered that her lifetime breast cancer risk was significantly higher than expected, despite having no family history or known major genetic mutations.
• Why atypical lobular hyperplasia can increase breast cancer risk and why understanding biopsy results matters when evaluating your personal risk.
• How Dr. Aliabadi's experience with preventive mastectomy ultimately led to an unexpected breast cancer diagnosis.
• Why breast cancer concerns can be dismissed in healthcare settings and how patients can advocate for further evaluation when something does not feel right.
• The six breast changes that warrant medical attention: a new or persistent lump, skin dimpling or other skin changes, nipple discharge, newly inverted nipples, persistent crusting or scaling of the nipple, and unusual redness or discoloration.
• The difference between routine self-breast examinations and breast awareness, including why it is important to recognize what is normal for your own body.
• How family history, breast density, previous biopsies, hormonal history, and other factors can contribute to an individual's breast cancer risk assessment.
• What the Tyrer-Cuzick risk assessment tool evaluates and how a lifetime risk estimate can help inform conversations about screening.
• Why dense breast tissue can both increase breast cancer risk and make abnormalities more difficult to identify on a mammogram.
• How 3D mammography, breast ultrasound, and breast MRI may be used in screening plans, depending on individual risk and clinical guidance.
• What genetic testing can reveal about inherited breast cancer risk, including mutations in genes such as BRCA.
• What polygenic risk scores measure and how numerous genetic variants may contribute to breast cancer risk even when a person does not have a major known genetic mutation.
• Why breast implants do not eliminate the need for appropriate breast awareness and screening.
• Why new or persistent breast changes should be evaluated by a healthcare professional, even in younger women or those without a family history of breast cancer.

Key Timestamps

00:00 Why women's breast cancer concerns can be dismissed

00:31 Six breast changes every woman should know

01:09 Dr. Thaïs Aliabadi's personal breast cancer journey

01:42 Understanding atypical lobular hyperplasia

04:34 Why Dr. Aliabadi decided to take action

07:55 Searching for a surgeon who would listen

09:58 The complications of preventive surgery

16:10 The unexpected breast cancer diagnosis

18:54 Finding purpose after a life-changing diagnosis

21:50 The six breast changes that warrant medical attention

23:33 Understanding what is normal for your breasts

24:37 Breast self-exams versus breast awareness

27:04 Why every woman should understand her personal risk

28:20 Using the Tyrer-Cuzick tool to estimate lifetime risk

30:22 How family history influences screening recommendations

34:01 Understanding average, intermediate, and high-risk categories

37:04 Why dense breasts can make cancer harder to detect

39:10 Why knowing your lifetime risk matters

40:35 Breast cancer risk factors and early detection

41:37 Genetic testing and polygenic risk scores explained

44:57 When to consider additional genetic risk assessment

46:54 Understanding breast cancer risk when a family member has a BRCA mutation

48:44 Reviewing the six breast changes you should never ignore

49:57 Why younger women should not dismiss breast symptoms

51:14 Advocating for yourself when your concerns are dismissed

Key Takeaways

• Breast cancer risk is not determined by family history alone. Dr. Aliabadi's experience demonstrates why a lack of known family history or a major genetic mutation does not eliminate the possibility of developing breast cancer. Personal risk assessment should consider multiple factors, including previous breast biopsies, breast density, and relevant medical and family history.
• Know what is normal for your breasts. Breast texture, tenderness, and fullness can change with menstrual cycles and hormonal fluctuations. Becoming familiar with your usual breast appearance and feel can help you recognize new or persistent changes that deserve medical attention.
• Recognize the six breast changes discussed in the episode. These include a new or persistent lump, skin dimpling or other visible skin changes, nipple discharge, newly inverted nipples, persistent crusting or scaling of the nipple, and unusual skin discoloration. These changes do not automatically indicate cancer, but they should be evaluated by a healthcare professional.
• Dense breast tissue can complicate cancer detection. Dense breasts contain more glandular and connective tissue relative to fat. Because both dense tissue and many breast cancers appear white on a mammogram, abnormalities can be harder to see. Breast density is also an independent risk factor, making it important to discuss appropriate screening options with a healthcare provider.
• Personalized risk assessment can help inform screening decisions. Tools such as the Tyrer-Cuzick model use information about family history and other risk factors to estimate lifetime breast cancer risk. Screening recommendations can vary depending on a person's risk profile, age, medical history, and applicable clinical guidelines.
• Genetic risk involves more than a single mutation. Genetic testing can identify inherited mutations associated with increased breast cancer risk. Polygenic risk scores assess the combined contribution of numerous genetic variants. These approaches provide different types of information and may help clinicians develop a more complete picture of risk when appropriate.
• Preventive decisions can involve difficult trade-offs. Dr. Aliabadi shares the physical challenges, uncertainty, and emotional weight involved in deciding to undergo preventive surgery. Her story highlights the importance of informed decision-making, individualized medical guidance, and having one's concerns taken seriously.
• Do not assume you are too young for a breast abnormality to matter. Although most breast changes are not cancerous, symptoms should not be dismissed based on age alone. Persistent or concerning changes warrant timely evaluation, and seeking another medical opinion may be appropriate when concerns remain unresolved.
• Patient advocacy is an important part of healthcare. Understanding your medical history, asking questions, requesting clarification about screening options, and seeking further evaluation when necessary can help you participate more actively in decisions about your health.
• Early detection and risk reduction are distinct but complementary goals. No screening strategy can prevent every breast cancer diagnosis. However, understanding personal risk, following an appropriate screening plan, and responding to new symptoms can support earlier detection and more informed care.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Why does sleep suddenly become so much harder for so many women in their 30s, 40s and 50s?

Eight Sleep cofounder Alexandra Zatarain joins SheMD to explore how hormones, temperature and the brain’s natural circadian rhythm affect the way women sleep throughout different stages of life.

Dr. Thaïs Aliabadi explains why fluctuations in estrogen and progesterone during perimenopause can contribute to night sweats, temperature changes, anxiety, racing thoughts and middle-of-the-night wake-ups.

Alexandra shares what years of sleep research and data have taught the Eight Sleep team about deep sleep, REM sleep, temperature regulation, pregnancy, menopause and recovery.

We also break down how much sleep adults actually need, why consistency matters and why alcohol, caffeine and late-night exercise may interfere with recovery even when you are technically getting enough hours.

Plus, Alexandra shares five practical habits she recommends for better sleep and helps us tackle common sleep myths, including whether you can really catch up on lost sleep over the weekend and whether a nightcap actually helps you sleep.

If your sleep has changed and you cannot figure out why, this episode is for you.

Sponsors

Eight Sleep is featured in this episode through a conversation with co-founder Alexandra Zatarain about sleep science and the company’s sleep technology. No formal sponsorship or promotional offer is mentioned.

What You’ll Learn

• How Alexandra Zatarain's personal experiences inspired the creation of Eight Sleep and its approach to improving sleep through technology.
• Why perimenopause and menopause can disrupt sleep, including the roles of fluctuating estrogen, declining progesterone, night sweats, and anxiety.
• How body temperature and circadian rhythms influence when we fall asleep, stay asleep, and wake up.
• Why pregnancy and postpartum hormonal changes can affect temperature regulation, snoring, and sleep quality.
• The differences between deep sleep and REM sleep, and why both are essential for physical recovery, memory, and emotional processing.
• How much sleep adults generally need, why individual sleep requirements vary, and how to recognize whether you're getting enough rest.
• Why alcohol may make it easier to fall asleep while negatively affecting overnight recovery.
• Why catching up on sleep over the weekend cannot fully compensate for consistently getting too little sleep during the week.
• How sleep-tracking technology can help monitor sleep patterns, recovery, temperature preferences, and potential signs of sleep apnea.
• Five practical ways to improve sleep, including prioritizing sufficient rest, maintaining a consistent schedule, optimizing your sleep environment, adjusting daily habits, and working with your partner.
• Why women experiencing persistent sleep disruptions should consider underlying factors, including hormonal changes and other health conditions, with guidance from a healthcare provider.

Key Takeaways

• Sleep is a foundational pillar of health. Prioritizing exercise and nutrition while consistently sacrificing sleep can undermine overall well-being. Making enough time for rest is an essential part of supporting long-term health.
• Hormonal changes can significantly disrupt women's sleep. Fluctuating estrogen and progesterone levels during perimenopause and menopause may contribute to temperature sensitivity, night sweats, anxiety, and nighttime awakenings. Persistent sleep difficulties deserve attention rather than being dismissed as an inevitable part of aging.
• Temperature plays an important role in sleep. Core body temperature naturally declines as we approach sleep and rises toward morning. A comfortable, cool sleeping environment can support this process, although individual temperature preferences vary.
• Deep sleep and REM sleep serve different but complementary functions. Deep sleep is associated with physical restoration, while REM sleep supports processes involving memory, learning, and emotional processing. Getting sufficient sleep allows the body to cycle through both.
• Alcohol can interfere with overnight recovery. Although alcohol may help someone fall asleep more quickly, it can affect recovery metrics, including resting heart rate and heart rate variability. Falling asleep faster does not necessarily mean sleeping well.
• Consistency matters as much as duration. Maintaining relatively consistent bedtimes and wake-up times can support the body's circadian rhythm. Alexandra recommends aiming for seven to nine hours of sleep for most adults while paying attention to individual needs.
• Sleep quality can be affected by more than personal habits. Snoring, possible sleep apnea, hormonal changes, stress, and a partner's sleep patterns can all contribute to disrupted rest. Persistent symptoms may warrant evaluation by a healthcare professional.
• Small, sustainable changes can improve sleep habits. Gradually extending sleep time, keeping the bedroom cool, dark, and quiet, limiting late-day caffeine and alcohol, and avoiding heavy meals close to bedtime are practical starting points.
• Women's sleep deserves more research and individualized care. Pregnancy, postpartum recovery, perimenopause, and menopause each present different challenges. Understanding these life stages can help inform better research, technology, and healthcare support.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Naomi Watts joins SheMD alongside renowned sexual arousal researcher Dr. Cindy Meston for a candid conversation about sex, desire and what happens to women’s bodies during perimenopause and menopause.

Naomi shares her experience learning in her 30s that she was likely entering early menopause, the shame and isolation she initially felt and how opening up about her changing body ultimately transformed her relationship with intimacy.

Dr. Meston explains why female sexual desire may work differently than many women have been taught, including why arousal can sometimes come before desire. She also breaks down the physical and psychological factors that can affect sex, from hormones, blood flow and vaginal changes to stress, sleep, body image and relationships.

Dr. Thaïs Aliabadi discusses treatment options for women experiencing painful sex, vaginal dryness and changes in libido, including vaginal moisturizers, lubricants, vaginal estrogen and testosterone.

Plus, Naomi explains why she believes menopause can be an empowering new chapter rather than the end of pleasure, intimacy or good sex.

Sponsors

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What You’ll Learn

• Why Naomi Watts' personal experience with early menopause inspired her to help change the conversation around women's health.
• The lesser-known symptoms of perimenopause and menopause, including brain fog, sleep disruption, dry eyes, vaginal dryness, and painful sex.
• How hormonal changes can affect vaginal health, lubrication, and urinary symptoms.
• Why sexual arousal can precede desire for many women, particularly during perimenopause and menopause.
• How stress, exercise, relationship dynamics, and negative thoughts can influence sexual arousal and intimacy.
• What treatment options are available for vaginal dryness and painful sex, including moisturizers, lubricants, vaginal estrogen, and other therapies.
• Why open communication with your partner and a knowledgeable healthcare provider is essential to navigating changes in sexual health.
• How Naomi's experiences and conversations with women inspired Stripes' sexual wellness products.
• Why menopause can be a new chapter of confidence, self-advocacy, and sexual fulfillment rather than the end of a satisfying sex life.

Key Timestamps

00:00 Naomi Watts on why good sex doesn't have an age limit

04:51 The overlooked symptoms of perimenopause and menopause

07:32 Vaginal dryness, painful sex, and recurring UTIs

12:32 How arousal, body image, and negative thoughts affect intimacy

18:55 Naomi's experience navigating menopause in a new relationship

22:08 The science of arousal, exercise, and blood flow

31:42 Vaginal estrogen and long-term vaginal health

40:31 How stress, sleep, and relationship dynamics affect desire

42:00 Why women should never feel they have to tolerate painful sex

45:24 The connection between psychological arousal, physical response, and communication

51:16 Testosterone therapy and the Mona Lisa laser

56:38 Naomi's menopause tips, favorite Stripes products, and rapid-fire questions

58:05 The language around menopause that needs to change

1:00:38 Dr. Meston's advice for women navigating menopause

1:02:29 Reframing menopause as an empowering new chapter

Key Takeaways

• Menopause affects more than hot flashes. Hormonal changes can influence sleep, mood, cognition, skin, eyes, vaginal health, and sexual comfort, sometimes years before menopause itself.
• Female desire and arousal don't always follow a linear pattern. For many women, particularly as they age, arousal can come before desire. Understanding this can help women move away from the expectation that sexual desire must always happen spontaneously.
• Sexual health involves both the mind and the body. Physical changes, stress, fatigue, body image, relationship dynamics, and distracting thoughts can all influence arousal and intimacy.
• Painful sex should not be accepted as an inevitable part of aging. Vaginal moisturizers, lubricants, vaginal estrogen, and other treatment options may help, depending on individual needs and medical history. Women experiencing persistent pain should seek guidance from a qualified healthcare provider.
• Communication can transform intimacy. Talking openly with a partner outside the bedroom about changing needs, comfort, and pleasure can help couples adapt and maintain connection throughout different stages of life.
• Women deserve individualized, evidence-informed care. There is no single approach to sexual health during menopause. Working with a clinician knowledgeable in menopause and sexual medicine can help women understand their options.
• Menopause is not the end of a fulfilling sex life. Naomi's story underscores the importance of challenging stigma, listening to women's experiences, and giving women the confidence to advocate for their health and pleasure.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We are revisiting one of our favorite SheMD conversations with SZA.

SZA joins her longtime physician Dr. Thaïs Aliabadi and Mary Alice Haney for an intimate conversation about her health, family history and the anxiety that can come with trying to understand what is happening inside your own body.

Dr. A walks through SZA’s breast cancer risk assessment, family history, genetic testing and why a negative genetic test does not necessarily mean someone has an average lifetime risk of breast cancer.

SZA also talks candidly about health anxiety, therapy, trauma, relationships, creativity and learning to accept the parts of herself that do not fit the traditional idea of being a “nice girl.” She reflects on the drive that helped build her career, why outside validation once mattered so much to her and what she is still learning about trusting herself.

Plus, SZA talks about getting off the internet, motherhood, life beyond music and the people who have shaped who she is today.

This conversation was originally recorded before SZA went on to win three Grammys following the release of SOS.

Subscribe to SHE MD Podcast for expert tips on PCOS, endometriosis, fertility, hormonal balance, mental health, and more. Share with friends and visit SHE MD website and Ovii for research-backed resources, holistic health strategies, and expert guidance on women's health and well-being.

Sponsors

Blueland: Get 15% off your first order at blueland.com/shemd.

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What You'll Learn

• Where the name SZA comes from and what each letter represents.
• Why every woman should know her lifetime risk of breast cancer, even without a family history.
• How factors like height, weight, breast density, family history, and genetic testing change a lifetime risk score.
• Why women with a lifetime risk above 20% should start breast imaging at 30 instead of 40.
• What a fibroadenoma is and why imaging catches cancers years before a lump can be felt.
• How a family history of cancer can create lasting health anxiety, and why being your own advocate matters.
• The story behind SOS and SZA's journey away from trying to be a "nice girl."
• SZA's advice for young artists on protecting their health and creativity.

Key Takeaways

• The average woman has a 12.5% lifetime risk of breast cancer, and every woman should have her personal risk calculated by her doctor.
• A negative genetic test does not mean low risk, since family history, breast density, and other factors still affect a woman's lifetime risk.
• Women with a lifetime risk above 20% should begin breast imaging at 30, not 40, and may be missed if risk is never calculated.
• By the time a lump can be felt, it has often been there for years, which is why regular imaging is essential.
• Watching loved ones go through cancer can create real health anxiety, and advocating for yourself is better than assuming something is nothing.
• Integrating every part of yourself, including your edge, can be a source of strength rather than shame.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Miranda McKeon was only 19 when she noticed a lump in her breast and was diagnosed with stage three, hormone positive, HER2 negative invasive ductal carcinoma. 

In honor of Breast Cancer Awareness Month, Miranda joins SheMD to share the full story of her diagnosis, treatment and life after breast cancer. She opens up about the breast dimpling she initially dismissed, learning she carried a CHEK2 mutation despite having no family history of cancer, freezing her eggs before chemotherapy, undergoing a double mastectomy and radiation, and entering medically induced menopause in her early 20s.

Miranda also talks candidly about painful sex, vaginal dryness, low libido, dating, body image, fertility and the emotional impact of experiencing cancer during what should have been her college years.

Dr. Thaïs Aliabadi explains breast changes women should pay attention to, how genetics and breast density can affect risk, and why knowing your own baseline and speaking up when something changes can matter.

This conversation is a powerful reminder that breast cancer does not only affect older women and that knowing your body is an important part of advocating for your health.

Subscribe to SHE MD Podcast for expert tips on PCOS, endometriosis, fertility, hormonal balance, mental health, and more. Share with friends and visit SHE MD website and Ovii for research-backed resources, holistic health strategies, and expert guidance on women’s health and well-being.

Sponsors

SmileSet: Listeners get an additional 35% off clear aligners at smileset.com/shemd.

Arca Wealth: Book a complimentary financial planning call with an Arca advisor at arcawealth.com/shemd. Arca Wealth is a fee-only fiduciary firm. This is a paid endorsement. See arcawealth.com for important disclosures.

AG1: For a limited time, get a free immune support bundle (omega-3 fish oil and vitamin D3 K2) with your first AG1 NextGen or AG1 Pro subscription order at drinkag1.com/shemd.

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Larine: Listeners get up to 50% off Larine remineralizing gum at buylarine.com/shemd.

What You'll Learn

• Why breast cancer rates are rising faster in women under 50, and why young women's symptoms are so often dismissed.
• The early signs of breast cancer beyond a lump, including skin dimpling, nipple changes, discharge, and persistent one-sided flaky skin.
• How CHEK2 mutations and polygenic risk scores shape breast cancer risk, even without a family history.
• Why a one-size-fits-all mammogram age misses individual risk, and how breast density, family history, and genetics change the picture.
• How to calculate your lifetime breast cancer risk with the Tyrer-Cuzick model and when high-risk screening should begin.
• How chemotherapy can affect fertility, and why egg freezing should come before treatment.
• What medically induced menopause looks like for a young woman, including hot flashes, low libido, and vaginal dryness.
• How vaginal estrogen and CO2 laser treatments can help with painful sex.
• How to cope emotionally with a young-onset diagnosis, from therapy to gratitude lists to a trusted inner circle.

Key Takeaways

• Breast cancer is more common after 50, but rates are rising faster in younger women, and one in six new invasive cases occurs before age 50.
• Skin dimpling and other changes are symptoms too. A young woman may not recognize them as warning signs, which can delay diagnosis.
• Most women diagnosed with breast cancer have no family history, so a lack of family history is not a guarantee of low risk.
• Mammograms starting at 40 treat everyone alike. Breast density, genetics, family history, and polygenic risk can all change when screening should begin.
• Every woman should know her lifetime breast cancer risk by 30. A risk of 20% or more means earlier imaging, which may include mammogram, ultrasound, and MRI.
• Egg freezing should be part of the first conversation before chemotherapy, because chemo's effect on ovarian reserve is unpredictable.
• Medically induced menopause can bring severe symptoms, including painful sex, and women shouldn't feel ashamed to bring them up with their doctors.
• A double mastectomy leaves some residual breast tissue, so ongoing monitoring is still important.
• Know what's normal for your breasts and report changes promptly.
• Therapy, gratitude, and a trusted circle can help you get through a young-onset diagnosis.

Guest Bio -  Miranda McKeon

Miranda McKeon is a breast cancer survivor, women’s health advocate, and content creator who was diagnosed with stage 3 hormone-positive, HER2-negative invasive ductal carcinoma at just 19 years old. After discovering a lump in her breast while home from college, Miranda underwent chemotherapy, a double mastectomy, radiation, and medically induced menopause. She later learned that she carries a CHEK2 genetic mutation associated with an increased risk of breast cancer.    

Since her diagnosis, Miranda has become an outspoken advocate for young women navigating cancer, sexual health, fertility, body image, and life after treatment. She openly shares her experience with intimacy and medically induced menopause and uses her platform to encourage women to understand their bodies and advocate for their health.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This one is a full-circle moment. Our guest isn't just one of Mary Alice's oldest friends (25 years and counting), she's also one of Dr. A's real-life patients, the doctor who actually froze her eggs. Whitney Cummings, comedian, actress, and creator of 2 Broke Girls and Whitney, has built a career saying the things women usually only whisper about. Today she says them out loud, with us.

Whitney was talking about freezing her eggs before it was a mainstream conversation (she did it at 33), and she is refreshingly, hilariously honest about getting pregnant at 40, being handed the term "geriatric pregnancy," the postpartum depression that came after her son, and the body image struggles she's carried for years. She and the hosts get into fertility, the real cost of waiting, why "biology is sexist," and the money advice she gives every young woman (skip the designer bag, save it for your eggs).

Funny, tender, and the kind of honesty that makes you feel less alone.

Subscribe to SHE MD Podcast for expert tips on PCOS, endometriosis, fertility, hormonal balance, mental health, and more. Share with friends and visit SHE MD website and Ovii for research-backed resources, holistic health strategies, and expert guidance on women's health and well-being.

Sponsors

Prolon: For a limited time, get 15% off sitewide plus a $40 bonus gift when you subscribe to the 5-day program. Visit prolonlife.com/shemd.

Egglife: Find Egglife egg white wraps in the fridge at Aldi, Whole Foods, Kroger, Target, Walmart, and more. Visit egglifefoods.com to find a retailer near you.

OHHO: Get 20% off your first order at ohho.co with code SheMD20.

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Skylight: Get $30 off the 15-inch Skylight Calendar at myskylight.com/shemd.

What You'll Learn

• Why Whitney froze her eggs at 33 and how it eased her anxiety about dating and timing.
• Why Dr. A tells patients never to use all of their frozen eggs to make embryos with a partner.
• How egg quantity and quality decline with age, and what that means for miscarriage risk.
• The lifestyle changes Whitney made before conceiving naturally at 40.
• The testing and monitoring Dr. A recommends for advanced maternal age pregnancies, including preterm birth screening, low-dose aspirin, and growth ultrasounds.
• Why delivery at 39 weeks is recommended for women over 40.
• The difference between postpartum blues and postpartum depression, and how long the postpartum period really lasts.
• Whitney's approach to co-parenting, forgiveness, and choosing a partner.

Key Takeaways

• Egg freezing can reduce the pressure and anxiety around timing, and women should always keep some of their own eggs rather than using them all for embryos with a partner.
• Both egg quantity and quality decline with age, but many women still have healthy pregnancies in their 40s with the right care and awareness of their personal risk factors.
• Advanced maternal age pregnancies benefit from closer monitoring, including preterm birth screening, low-dose aspirin, regular growth ultrasounds, and delivery at 39 weeks.
• Postpartum depression affects about one in seven women, can appear up to a year after birth, and is more likely without strong support at home.
• Asking for help, leaning on your village, and letting motherhood change you are essential parts of postpartum recovery.
• Choosing a partner based on respect and integrity, and co-parenting with kindness, creates a healthier environment for your child.

Guest Bio - Whitney Cummings

Whitney Cummings is a comedian, actress, director, and writer. She is the co-creator of 2 Broke Girls, the creator and star of NBC's Whitney, and the host of the podcast Good for You. Known for her disarmingly honest stand-up specials, Whitney has spoken openly about egg freezing, body image, sobriety, and her recovery from an eating disorder. She became a mom at 40 to her son Henry and has been candid about her pregnancy and postpartum journey.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What does it actually mean to age well as a woman?

Dr. Elizabeth Poynor joins SheMD to explore longevity through a female and hormonal lens. Drawing on her background in gynecologic oncology, cancer prevention and women’s health, she explains why midlife can be a critical turning point and what may begin changing in the body years before menopause.

Dr. Poynor breaks down the roles of estrogen, progesterone and testosterone, including their connections to sleep, mood, brain fog, body composition, metabolic health and overall well-being. She also discusses hormone therapy, GLP-1s, protein intake, strength training, genetic testing, cancer prevention and why she believes movement is one of the most important habits women can build for long-term health.

Plus, Dr. Poynor shares her own experience with BRCA1, why she believes women should take a more proactive approach to prevention, and the mindset shift she wants women to make about aging.

Midlife is not just something to get through. It may be one of your greatest opportunities to take control of how you age.

Sponsors

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What You’ll Learn

• Why midlife is a critical window for women to take a proactive approach to longevity and health
• How hormonal changes in the late reproductive years can affect sleep, mood, brain health, metabolism, and body composition
• The role of strength training, protein, sleep, nutrition, and stress management in healthy aging
• What women should know about hormone therapy, including estrogen, progesterone, and testosterone
• How GLP-1 medications may fit into midlife health and body composition, and why maintaining muscle is so important
• Why women’s longevity needs to be understood through a hormonal lens—and where more research is still needed

Key Timestamps

00:00 Welcome to SHE MD Podcast

00:41 From Oncologist To Longevity Expert

04:04 Why Cancer Rates Are Rising

05:11 Genetic Testing And BRCA Story

07:47 Foundational Pillars For Health

09:42 Protein Intake For Midlife Women

11:44 GLP-1s And Body Composition

19:19 The Midlife Hormonal Turning Point

26:44 When To Start Hormone Therapy

31:46 Oral Vs Transdermal Estrogen

41:07 Progesterone And Testosterone Explained

46:37 Why Midlife Is A Critical Window

50:03 Movement As The Top Longevity Habit

51:12 Peptides: Where The Research Stands

53:10 Women's Longevity Vs Men's

Key Takeaways

• Midlife is a critical opportunity to take a proactive approach to health and longevity.
• Hormonal changes can impact sleep, mood, brain health, metabolism, and body composition.
• Strength training and daily movement are foundational for healthy aging.
• Protein and muscle preservation become increasingly important as women age.
• Hormone therapy should be personalized and discussed with a knowledgeable healthcare professional.
• More research is needed on hormones, GLP-1s, peptides, and women’s longevity.
• Healthy habits built earlier in life can create a stronger foundation for long-term health.
• Women’s longevity should be studied through a female-specific hormonal lens.

Guest Bio - Dr. Elizabeth Poyner

Dr. Elizabeth Poynor is a board-certified gynecologic oncologist, pelvic surgeon, and women’s health expert specializing in menopause, hormone health, and complex gynecologic conditions. She is Chair of Women’s Health and Gynecology at the Atria Health and Research Institute and a Clinical Professor at NYU Grossman School of Medicine. She combines her expertise in gynecologic oncology, surgery, and midlife women’s health to help women better understand and navigate their health.

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.