The Incubator

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Please find the list of articles discussed in this week’s journal club with links to the full text.

01:36 - Hypothermia for moderate or severe neonatal encephalopathy in low-income and middle-income countries (HELIX): a randomised controlled trial in India, Sri Lanka, and Bangladesh. https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(21)00264-3/fulltext

16:48 - Preterm or Early Term Birth and Risk of Autism. https://pediatrics.aappublications.org/content/early/2021/08/10/peds.2020-032300

25:40 - Neonatal resuscitation in the NICU; Challenges beyond NRP. https://onlinelibrary.wiley.com/doi/10.1111/apa.16057

31:15 - Improving Compliance with a Rounding Checklist through Low- and High-technology Interventions: A Quality Improvement Initiative. https://journals.lww.com/pqs/Fulltext/2021/07000/Improving_Compliance_with_a_Rounding_Checklist.21.aspx

38:59 - Initial Laparotomy Versus Peritoneal Drainage in Extremely Low Birthweight Infants With Surgical Necrotizing Enterocolitis or Isolated Intestinal Perforation: A Multicenter Randomized Clinical Trial. https://journals.lww.com/annalsofsurgery/Abstract/9000/Initial_Laparotomy_Versus_Peritoneal_Drainage_in.93407.aspx

51:27 - Automated Explainable Multidimensional Deep Learning Platform of Retinal Images for Retinopathy of Prematurity Screening. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2779454

54:00 - Neonatal mortality prediction with routinely collected data: a machine learning approach. https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-021-02788-9

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Dr. Brodsky and Dr. Martin are the authors of the renowned books titled Neonatology Review. This series, well known to every neonatal trainee, is currently in its third edition. They have also published other books including Neonatology Review Images and Neonatology Review: Questions & Answers.

Dr. Dara Brodsky is an Associate Professor at Harvard Medical School. She is the Director of Education for the department of Neonatology at Beth Israel Deaconess Medial Center. She is also the Editor-in-Chief of NeoReviews.

Dr. Camilia R. Martin is an Associate Professor of Pediatrics at Harvard Medical School, and the Associate Director of the Neonatal Intensive Care Unit and Director for Cross-Disciplinary Research Partnerships in the Division of Translational Research at Beth Israel Deaconess Medical Center Boston, MA.

You can in touch with them by email at:
Dr. Brodsky: [email protected]
Dr. Martin: [email protected]

Their books can be purchased at the following website:
https://www.lulu.com/spotlight/neonatologyreview/

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As always, feel free to send us questions, comments or suggestions to our email: [email protected]. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. Papers discussed in today's episode are listed and timestamped below.
enjoy!

Support the show

As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

Enjoy!

Send us Fan Mail

As always, feel free to send us questions, comments or suggestions to our email: [email protected]. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. Papers discussed in today's episode are listed and timestamped below.
enjoy!
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Please find the titles and links to the articles mentioned in this week's journal club and timestamps for your convenience:

02:30 - Effect of Systemic Hydrocortisone Initiated 7 to 14 Days After Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years’ Corrected Age: Follow-up of a Randomized Clinical Trial. https://jamanetwork.com/journals/jama/article-abstract/2782313

07:50 - Postnatal Corticosteroids to Prevent or Treat Bronchopulmonary Dysplasia. https://www.karger.com/Article/FullText/515950

18:30 - Temporal Trends in Neurodevelopmental Outcomes to 2 Years After Extremely Preterm Birth. https://jamanetwork.com/journals/jamapediatrics/article-abstract/2782149

26:00 - An assessment of dexmedetomidine as an opioid-sparing agent after neonatal open thoracic and abdominal operations. https://www.nature.com/articles/s41372-021-01175-7

32:23 - Association of time of day and extubation success in very low birthweight infants: a multicenter cohort study. https://www.nature.com/articles/s41372-021-01168-6

39:27 - Caffeine citrate for apnea of prematurity—One dose does not fit all a prospective study. https://www.nature.com/articles/s41372-021-01172-w

43:40 - Early High-Dose Caffeine Improves Respiratory Outcomes in Preterm Infants. https://www.mdpi.com/2227-9067/8/6/501

48:35 - Low Rate of Spontaneous Closure in Premature Infants Discharged with a Patent Ductus Arteriosus: A Multicenter Prospective Study. https://jpeds.com/retrieve/pii/S0022347621007022

55:36 - Effects of single family room architecture on parent–infant closeness and family centered care in neonatal environments—a single-center pre–post study. https://www.nature.com/articles/s41372-021-01137-z

60:53 - Asynchronous telemedicine for clinical genetics consultations in the NICU: a single center’s solution. https://www.nature.com/articles/s41372-021-01070-1

64:00 - Cortical hemodynamic activity and pain perception during insertion of feeding tubes in preterm neonates: a randomized controlled cross-over trial. https://www.nature.com/articles/s41372-021-01166-8

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As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

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Dawn Raffel's book: The Strange Case of Dr. Couney was chosen as one of NPR’s best books of 2018 and awarded a 2019 Christopher Award for books that affirm the highest values of the human spirit. 

As Dawn Raffel recounts, Dr. Couney used incubators and careful nursing to keep previously doomed infants alive, while displaying these babies alongside sword swallowers, bearded ladies, and burlesque shows at Coney Island, Atlantic City, and venues across the nation. How this turn-of-the-twentieth-century émigré became the savior to families with premature infants—known then as “weaklings”—as he ignored the scorn of the medical establishment and fought the rising popularity of eugenics is one of the most astounding stories of modern medicine. Dr. Couney, for all his entrepreneurial gusto, is a surprisingly appealing character, someone who genuinely cared for the well-being of his tiny patients.

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As always, feel free to send us questions, comments or suggestions to our email: [email protected]. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd.

Enjoy!

Support the show

As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

Enjoy!

Send us Fan Mail

As always, feel free to send us questions, comments or suggestions to our email: [email protected]. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. Papers discussed in today's episode are listed and timestamped below.
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01:50 - Reviewing recordings of neonatal resuscitation with parents. https://fn.bmj.com/content/106/4/346

10:55 - Associations between family presence and neonatal intubation outcomes: a report from the National Emergency Airway Registry for Neonates: NEAR4NEOS https://fn.bmj.com/content/106/4/392

19:28 - A Retrospective Review Following the Addition of Clonidine to a Neonatal Abstinence Syndrome Treatment Algorithm. https://www.frontiersin.org/articles/10.3389/fped.2021.632836/full

25:03 - Trial of aerosolised surfactant for preterm infants with respiratory distress syndrome. https://fn.bmj.com/content/early/2021/06/09/archdischild-2021-321645

30:15 - Interface leakage during neonatal CPAP treatment: a randomised, cross-over trial. https://fn.bmj.com/content/early/2021/06/28/archdischild-2021-321579

33:55 - Changes in Physicians' Perceptions and Practices on Neonatal Pain Management Over the Past 20 Years. A Survey Conducted at Two Time-Points. https://www.frontiersin.org/articles/10.3389/fped.2021.667806/full

39:02 - The Experience of Housing Needs Among Families Caring for Children With Medical Complexity. https://pediatrics.aappublications.org/content/148/1/e2020018937

47:10 - Home Visiting for NICU Graduates: Impacts of Following Baby Back Home. https://pediatrics.aappublications.org/content/148/1/e2020029397

52:25 - An Infant Carrier Intervention and Breastfeeding Duration: A Randomized Controlled Trial. https://pediatrics.aappublications.org/content/148/1/e2020049717

56:37 - Severity of Bronchopulmonary Dysplasia Among Very Preterm Infants in the United States. https://pediatrics.aappublications.org/content/148/1/e2020030007

58:41 - Human milk feeding and cognitive outcome in preterm infants: the role of infection and NEC reduction. https://www.nature.com/articles/s41390-021-01367-z

61:27 - Validity of Random Triglyceride Levels in Infants Receiving Parenteral Nutrition. https://www.frontiersin.org/articles/10.3389/fped.2021.601915/full

62:40 - Degree of ventriculomegaly predicts school-aged functional outcomes in preterm infants with intraventricular hemorrhage. https://www.nature.com/articles/s41390-021-01631-2

Support the show

As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

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Juliette Lee is a pediatric nurse from Cambridge in the U.K. She was born extremely preterm in the 1990's and has since worked with other adult preterm to create the adult premie advocacy network (www.adultpreemies.com). 
She also took part in a large study of former preterm adults that you can find at the following link: https://pubmed.ncbi.nlm.nih.gov/31732683/
This was undoubtedly a great discussion.

Enjoy!

As always, feel free to send us questions, comments or suggestions to our email: [email protected]. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd.

Support the show

As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

Enjoy!

Send us Fan Mail

As always, feel free to send us questions, comments or suggestions to our email: [email protected]. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. Papers discussed in today's episode are listed and timestamped below.
enjoy!

03:35 - https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2781459
14:35 - https://jpeds.com/retrieve/pii/S0022347620315675
23:35  - https://jpeds.com/retrieve/pii/S0022347621002298
28:40 -  https://dx.doi.org/10.1016/j.jpeds.2021.03.046
40:08 - https://www.jpeds.com/article/S0022-3476(21)00219-5/fulltext
47:45 - https://www.jpeds.com/article/S0022-3476(21)00114-1/fulltext
51:48 -  https://www.nature.com/articles/s41372-021-01097-4
57:08 - https://www.nature.com/articles/s41372-020-00808-7
63:20 - https://www.nature.com/articles/s41372-021-01082-x
68:04 - https://www.nature.com/articles/s41372-021-00988-w
70:35 - https://www.nature.com/articles/s41372-020-00911-9
74:40 -  https://www.nature.com/articles/s41372-020-0746-6
77:14 -  https://www.nature.com/articles/s41372-021-01021-w
78:30 -  https://www.nature.com/articles/s41372-020-00850-5
81:02 -  https://www.nature.com/articles/s41372-021-01081-y
82:38 -  https://www.nature.com/articles/s41372-021-01035-4
83:50 - https://www.nature.com/articles/s41372-021-00963-5

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As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

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Dr. Katherine Horan is a neonatologist from Baystate Medical Center in Springfield Massachusetts. She has gone on multiple field missions with Doctors Without Borders in West Africa. She recounts her experience in various settings including Chad, South Sudan, Mali and the Ivory Coast. 

She also gives amazing tips on how to get started in global health work for anyone interested.

Enjoy!

As always, feel free to send us questions, comments or suggestions to our email: [email protected]. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd.

Support the show

As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

Enjoy!

Send us Fan Mail

As always, feel free to send us questions, comments or suggestions to our email: [email protected]. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd. Papers discussed in today's episode are listed and timestamped below.
enjoy!



06:05 - Extremely Low Birth Weight and Accelerated Biological Aging. https://pediatrics.aappublications.org/content/147/6/e2020001230

13:48 - Early Determination of Prognosis in Neonatal Moderate or Severe Hypoxic-Ischemic Encephalopathy. https://pediatrics.aappublications.org/content/147/6/e2020048678

19:55 - Use of Probiotics in Preterm Infants.h ttps://pediatrics.aappublications.org/content/147/6/e2021051485

23:20 - Use of Probiotics to Prevent Necrotizing Enterocolitis. https://jamanetwork.com/journals/jamapediatrics/article-abstract/2780228

28:00 - Comparison of Respiratory Support After Delivery in Infants Born Before 28 Weeks’ Gestational Age. https://jamanetwork.com/journals/jamapediatrics/article-abstract/2780513

40:49 - Parent–infant skin-to-skin contact reduces the electrical activity of the diaphragm and stabilizes respiratory function in preterm infants. https://www.nature.com/articles/s41390-021-01607-2

51:00 - Lung mechanics and respiratory morbidities in school-age children born moderate-to-late preterm. https://www.nature.com/articles/s41390-021-01538-y

59:00 - Early prediction of neurodevelopmental outcomes at 12 years in children born extremely preterm. https://www.nature.com/articles/s41390-021-01564-w

Support the show

As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

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Betsy Pilon is the executive director of the nonprofit organization HOPE FOR HIE. Hope for HIE provides awareness, education and support to families and providers dealing with neonatal and pediatric hypoxic ischemic encephalopathy.  Learn more at www.hopeforhie.org or on twitter @HopeforHIE

Check out the other half of this discussion on just say HIE (hope for HIE's podcast) where we delve into the challenges and opportunities that clinicians face during the care of  patients stricken by HIE.

As always, feel free to send us questions, comments or suggestions to our email: [email protected]. You can also contact the show through instagram or twitter, @nicupodcast. Or contact Ben and Daphna directly via their twitter profiles: @drnicu and @doctordaphnamd.

Support the show

As always, feel free to send us questions, comments, or suggestions to our email: [email protected]. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.

Enjoy!