In this episode of FYI: For Your Innovation, ARK’s Chief Futurist Brett Winton and ARK Analyst Nemo Despot chat with Harvard Professor Dr. Mahmood, a trailblazer in computational pathology. Together, they explore how AI and multiomics are reshaping healthcare and drug discovery. The discussion spans the transformative potential of combining data modalities like histology, genomics, and molecular profiling with advanced AI models. Dr. Mahmood shares his journey into computational pathology and highlights breakthroughs in applying machine learning to diagnostics and drug discovery. They also delve into the regulatory landscape, the transition from analog to digital pathology, and how foundational models are accelerating innovation. This episode offers a glimpse into the near future of healthcare, where AI-driven insights enable more predictive, personalized, and efficient medicine.

Key Points From This Episode:

• An introduction to multiomics: integrating biological data like DNA, RNA, and protein for deeper insights.
• The role of computational pathology in transforming diagnostics and drug discovery.
• Challenges and opportunities in transitioning pathology from analog to digital systems.
• How AI models are enhancing outcomes in diagnostics and therapy predictions.
• Real-world applications of AI in clinical trials and drug discovery pipelines.
• Regulatory and reimbursement hurdles in adopting digital and AI-driven pathology.
• Insights into foundational AI models and their application in healthcare.
• Examples of how multimodal data enhances disease discovery and treatment development.
• The future of diagnostic healthcare using specific AI models trained on biological data.
• Predictions on the pace of AI advancement in medical research and clinical practice.