Imagine a nanoparticle, less that a thousandth of the width of a human hair, that is so precise that it can carry a medicine to just where it’s needed in the body, improving the drug’s impact and reducing side effects.

Presented by JIm Al-Khalili

Darren Croft studies one of the ocean’s most charismatic and spectacular animals – the killer whale. Orca are probably best known for their predatory behaviour: ganging up to catch hapless seals or attack other whales. But for the last fifteen years, Darren Croft’s focus has been on a gentler aspect of killer whale existence: their family and reproductive lives .

Presented by Jim Al-Khalili

Bill Gates is one of the world's best-known billionaires - but after years at the corporate coalface building a software empire and a vast fortune, his priority now is giving that wealth away. And his ethos for doing it has been shaped by science.

Famed for co-founding Microsoft, in recent decades Bill’s attention has turned to philanthropy via The Gates Foundation: one of the largest charities in the world. Since its inception in 2000, the organisation's helped tackle issues around health, education, inequality and climate change in some of the world’s poorest countries, with an undeniable impact: from contributing to the eradication of wild poliovirus in Africa, to helping halve global child mortality rates within 25 years.

But, as Jim Al-Khalili discovers, for a man with lofty ambitions and an even loftier bank balance Bill has surprisingly humble tastes - from cheeseburgers and a bingeable spy series, to a good game of pickleball...

Presented by Jim Al-Khalili

The final episode in this series of The Life Scientific is a journey through space and time, via black holes and wormholes, taking in Nobel-prize-winning research and Hollywood blockbusters!

Kip Thorne is an Emeritus Professor of Theoretical Physics at Caltech, the California Institute of Technology, and someone who’s had a huge impact on our understanding of Einsteinian gravity. Over the course of his career Kip has broken new ground in the study of black holes, and been an integral parts of the team that recorded gravitational waves for the very first time – earning him a share in the 2017 Nobel Prize for Physics.

He went on to promote physics in films: developing the original idea behind Christopher Nolan’s time-travel epic Interstellar and, since then, advising on scientific elements of various big-screen projects; including, most recently, the Oscar-winning Oppenheimer.

In a special edition of The Life Scientific recorded in front of an audience of London’s Royal Institution, Professor Jim Al-Khalili talks to Kip about his life and career, from his Mormon upbringing in Utah to Hollywood collaborations – all through the lens of his unwavering passion for science.

Presented by Jim Al-Khalili

It's summer - no really - and although the weather might have been mixed, the sporting line-up has been undeniably scorching - from the back-and-forth of Wimbledon, to the nail-biting Euros, to the current pageantry of the Summer Olympics.

Next month the 2024 Paralympic Games get underway in Paris, involving the world’s very best para athletes; and Professor Vicky Tolfrey is at the forefront of the science that makes their sporting dreams a reality.

Vicky is the Director of the Peter Harrison Centre for Disability Sport at Loughborough University, a hub for elite para-sport research. She’s worked with stars from the worlds of wheelchair athletics, basketball, rugby and tennis, amongst others – and in 2017, became the first European recipient of the International Paralympic Committee’s prestigious Scientific Award.

She tells Professor Jim Al-Khalili about her work with elite para athletes, her experiences at major international sporting events, and her childhood dreams of becoming an Olympian herself.

Presented by Jim Al-Khalili

The engineering industry, like many other STEM sectors, has a problem with diversity: one that Dawn Bonfield believes we can and must fix, if we're to get a handle on much more pressing planetary problems...

Dawn is a materials engineer by background, who held roles at Citroën in France and British Aerospace in the UK. But, after having her third child, she made the difficult decision to leave the industry - as she thought at the time, for good. However a short spell working in post-natal services and childcare gave her new skills and a fresh perspective. This led to Dawn rehabilitating the struggling Women in Engineering Society and creating ‘International Women In Engineering Day’, which has just celebrated its 10th anniversary.

Today, she’s Professor of Practice in Engineering for Sustainable Development at King’s College London, and the founder of Magnificent Women: a social enterprise celebrating the story of female engineers over the past century. She’s also President of the Commonwealth Engineers’ Council and has had her work supporting diversity and inclusion recognised with an MBE.

Dawn talks to Professor Jim Al-Khalili about why 'inclusive engineering' should not be dismissed as tokenism, and why she's optimistic about the engineering sector's power to change the world.

Presented by Jim Al-Khalili

In recent decades, we've taken huge steps forward in treating formerly fatal viruses: with pharmacological breakthroughs revolutionising treatment for conditions such as HIV, hepatitis and herpes.

Raymond Schinazi has played a big role in that revolution.

Ray was born in Egypt, where his mother’s brush with a potentially deadly illness during his childhood inspired a fascination with medicine. His childhood was scattered: after his family were forced to leave their homeland and travelled to Italy as refugees, Ray ended up on a scholarship to a British boarding school - and subsequently went on to study and flourish in the world of chemistry and biology.

Today, Ray is the Director of the Laboratory of Biochemical Pharmacology at Emory University in Atlanta, where he also set up the renowned Center for AIDS Research.

Speaking to Jim Al-Khalili, Ray reflects on his route to success - and explains why he's confident that more big breakthroughs are on the horizon.

Presented by Jim Al-Khalili

From anorexia nervosa to binge-eating, eating disorders are potentially fatal conditions that are traditionally very difficult to diagnose and treat - not least because those affected often don’t recognise that there’s anything wrong. But also because of the diverse factors that can influence and encourage them.

Janet Treasure is a Professor of Psychiatry at King’s College, London - where she's focused on understanding the drivers behind these disorders, to help develop more effective treatments. Her study of twins in the 1980s offered one of the earliest arguments of a genetic link to anorexia, rather than the purely psychological motivations accepted at the time; while her most recent work explores holistic ways to better treat these conditions.

Speaking to Jim Al-Khalili, Janet explains the work that's revealed anorexia's roots in both body and mind - as well as how attitudes towards eating disorders are slowly changing.

Presented by Jim Al-Khalili

Marfan syndrome is a genetic disorder that makes renders the body’s connective tissues incredibly fragile; this can weaken the heart, leading to potentially fatal aneurysms. What’s more, anyone with the condition has a 50/50 chance of passing it on to their children.

Dr Anne Child is a clinical geneticist who’s dedicated her professional life to finding answers and solutions for people affected by Marfan’s.

Born in Canada, she met her British future-husband while working in Montreal in a case she describes as "love at first sight" - and in the 1970s she relocated her life to the UK.

There, an encounter with a Marfan patient she was unable to help set Anne on a career path for life. She subsequently established the team that discovered the gene responsible for Marfan's, and founded the Marfan Trust to drive further research. Since then, life expectancy for those with the condition has jumped from 32 years old, to over 70.

Speaking to Professor Jim Al-Khalili, Anne shares how she and her team achieved this remarkable turnaround.

Presented by Jim Al-Khalili

Many of us have heard of seismology, the study of earthquakes; but what about asteroseismology, focusing on vibrations in stars?

Conny Aerts is a Professor of Astrophysics at the University of Leuven in Belgium - and a champion of this information-rich field of celestial research. Her work has broken new ground in helping to improve our understanding of stars and their structures.

It hasn’t been an easy path: Conny describes herself as always being “something of an outlier” and she had to fight to follow her dream of working in astronomy.

In an epsiode recorded at the 2024 Cheltenham Science Festival, Professor Jim Al-Khalili talks to the pioneering Belgian astrophysicist about her lifelong passion for stars, supporting the next generation of scientists, and her determination to tread her own path.

Presented by Jim Al-Khalili