Program notes:

0:40 Aldosterone as a risk factor for heart disease

1:40 Spectrum of renin-aldosterone levels

2:40 As many as 25-30% may have

3:11 All pharmacologic interventions for obesity tx

4:14 All effective compared with placebo

5:12 Meta-analysis 

6:13 Very little data in overweight or massively obese

6:35 Where do U.S. antibiotics come from?

7:35 India leading country for finished product

8:20 Environmental impact of inhalers

9:20 Annual emissions increased by 24%

10:23 Decreased by 43%

11:23 Three forms of inhaler

12:40 End

Program notes:

1:21 Bronchiectasis treatment

2:22 Twenty sites in UK

3:20 Medical imaging and cancer risk in kids

4:20 3000 hematologic cancers

5:20 Consider other types of imaging

6:23 Head CT increases risk by 35%

7:24 Treating pulmonary arterial hypertension

8:24 Improved mortality in another trial

9:25 Antibody prevention of RSV in healthy infants

10:25 Healthy preterm and full term infants

11:25 Argues for use of this antibody globally

12:25 Antibodies against antibody didn't compromise

13:08 End

Program notes:

0:40 Private equity takeover of hospitals

1:40 Reduced salaries or staffing

2:40 Patients likely to cost system

3:30 Use of anti thymocyte globulin to slow down T1D in youth

4:30 Diagnosed within 9 weeks prior

5:30 Serum sickness in 82% of highest dose group

6:30 Incidence increasing by 2% per year over 20 years

7:00 Aspirin in CRC

8:00 1100 patients with mutation

9:00 Can this mutation be acquired?

9:15 Alcohol and dementia

10:15 Confounding factors relative to alcohol use

11:15 Is there a safe level of consumption?

12:40 End

Program notes:

0:45 Intimate partner violence and CVD

1:45 12% reported stalking

2:46 Screening in primary care

3:47 Fifty to 200% increased risk

4:00 Number of psychiatric disorders and dementia risk

5:00 Important to be aware when mental health disorders exist

6:03 Anxiety and depression associated

6:33 Lipoprotein(a) and widespread vascular disease

7:31 High risk of extracoronary vascular disease

8:32 Also associated with complications

9:32 Unknown why some areas affected

10:00 Second cancers after early invasive breast cancer

11:00 Contralateral breast cancer greater in younger women

12:00 Not excessive risk

13:31 End

Program notes:

0:45 LSD and treatment of generalized anxiety disorders

1:45 Change in anxiety score to 12 weeks post administration

2:45 100 micrograms appear most efficacious

3:45 Require inpatient 12 hours

4:44 Cardiac rehab in older patients after MI

5:44 Frail individuals can improve outcome

6:45 Oftentimes think it won't make a difference

7:10 CT and pregnancy outcomes

8:10 Linear relationship with increasing CT scans

9:10 Closer to conception more likely 

10:10 Sometimes not really necessary

10:21 New tx for resistant hypertension

11:20 Baxdrostat inhibits aldosterone

12:20 What happens when aldosterone drops

13:07 End

Program notes:

0:53 Who needs a beta blocker after MI

1:53 Those with mild reduction of ejection fraction

2:53 Confined to those with 40-50% ejection fraction

3:15 Revascularization in NSTEMI

4:20 Composite outcome

5:20 Closes gap, do FFR

6:20 May not be physiologically significant

6:40 Is lifelong anticoagulation needed after ablation

7:41 Occurred less in those who stopped

8:30 RSV, cardiac events and hospitalizations

9:30 Lower hospitalization in those who got the vaccine

10:30 Acute respiratory illness hospitalization

11:30 Less benefit with existing CVD or immunocompromise

12:15 Several RSV vaccines

13:16 End

Program notes:

0:44 Drug prices around the world

1:41 German prices as standard

2:40 Wide variation in price and affordability

3:40 Generic pricing 

4:20 ADHD meds and behavior choices

5:20 Largely treated with methylphenidate

6:20 Significantly impacted suicidality and other behaviors

6:49 AI assistance and colonoscopy skills

7:49 When you stop AI assistance

8:50 Does this apply to other procedures that use AI

9:20 Trauma predictive brain networks

10:20 Use of hydrocortisone to damp down

11:20 Previous trauma impact

12:25 Developmental timing

13:30 End

Program Notes:

0:44 Spuds are what we call potatoes

1:47 Followed for over 5million person years

2:45 No mechanism for why french fries are problematic

3:25 DASH4D diet for glycemic control

4:25 4 diets compared 

5:25 Extends benefits outside hypertension

6:20 A new antibiotic for staph infections

7:20 IV therapy until cultures are negative

8:20 Cost of new therapy, cost effectiveness

8:40 Geographic variation in subspeciality cancer care

9:40 Highest income managed by specialists

10:40 Guidelines expanded

11:36 Telemedicine may help

12:10 End

Program notes:

0:40 Alteplase after stroke

1:40 Expand time window

2:40 Imaging crucial in use

3:20 Use of health care and mortality in those with dementia

4:20 Women used much less healthcare

5:20 Focus on prevention in women

5:50 IVF outcomes and weight loss

6:50 Did not appear to increase success with IVF

7:45 Ultraprocessed foods versus minimally processed foods

8:45 Randomized to one diet or the other for 8 weeks

9:45 Minimally processed foods improved risk factors

10:45 Short period of study

11:42 End

Program notes:

0:40 Screening young adults for CRC

1:40 Four different screening options

2:41 Awareness issue

3:40 "Yuck" factor associated

4:34 Persistent Covid infections and variants

5:35 Who ends up with variants?

6:35 Did not render more infectious

7:35 Humans as mixing vessels

7:50 How do men and women respond to antithrombotics

8:50 15% reduction in MI

9:58 Long term contraceptives free and uptake

10:58 48% of pregnancies in North America unintended

11:58 Increase in any type of contraception

12:38 Cost is an important contributor

13:24 End