TWiV reviews cases of measles in Brooklyn NY and Washington DC, stalling of global childhood vaccination, licenses H5N1 vaccines protect against circulating strains, viruses traveling without passports. OC43 SARS-CoV- 2 spike replacement virus as an improved BSL-2 proxy virus for SARS-CoV-2 neutralization assays, and deep mutational scanning reveals functional constraints and antibody-escape potential of Lassa virus glycoprotein complex.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

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Links for this episode

• MicrobeTV Discord Server
• Measles in Brooklyn NY (ABC)
• Measles in Washington DC (DC Health)
• Global childhood immunization stalls (WHO)
• Licensed H5N1 vaccines protect against circulating strains (Nat Med)
• Viruses moving without passports (European CDC)
• OC42-SARS-CoV-2 replacement spike virus (PNAS)
• Deep mutational scanning of Lassa virus glycoprotein (Immunity)
• Letters read on TWiV 1133
• Timestamps by Jolene. Thanks!

Weekly Picks

Dickson – Elemental sulfur found on Mars Kathy – Lennette Lectures at ASV, including Gail Wertz, ASV 2024 Rich – Electricity maps (Opinions: Nuclear Waste Is Misunderstood; Should We Be Worried About Nuclear Waste?) Alan – Nature sent an investigative reporter to a predatory conference Vincent – Coal-filled trains are likely sending people to the hospital

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]

Content in this podcast should not be construed as medical advice.