TWiV kicks off 2022 with a review of the virology highlights of 2021, from three virologists, one immunologist, a science writer, and a partridge in a pear tree. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode COVID vaccines: TWiV 708, 715, 718, 844 Non-CoV papers: TWiV 763, 784, 819, 822, 740, 848 Immune correlates of protection: TWiV 791, 799, 835, 832, 841, 789 Fitness: TWiV 705, 836, 768, 757 Guests off beaten track: 723, 726, 732, 838, 773, 745 Lab leak nonsense: TWiV 762, 774 One Health/Viruses in Wildlife: TWiV 799, 722, 771, 809, 798, 759, 791, 847, 750, 821, 824, 804 Timestamps by Jolene. Thanks! Weekly Picks Brianne – Don’t Look Up Kathy – spaceweather.com Rich – Video of a Green Flash  (wiki) Alan – Fungally-modified violins Vincent – This Old Tony especially this segment Listener Picks Paul – Deep Mind and AlphaFold Grant – SARS-CoV-2 reproduction cycle Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]