In COVID-19 clinical update #100, Daniel Griffin, from Accra, Ghana, reviews the challenges in evaluating Omicron severity, over 800 deaths in children, Pfizer vaccine EUA application for under 5 year olds, false positives from soft drinks, Novavax vaccine EUA application, childhood experiences and vaccine hesitancy, fourth vaccine dose in Israel, effects of antivirals and monoclonals against Omicron, and multiple factors associated with PASC. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Omicron severity challenges (NEJM) Children and COVID data (AAP) Vaccine EUA for under 5 year olds (Pfizer) B cell boot camp (Immune 52) Soft drink and LFA false positives (medRxiv) EUA application for Novavax vaccine (Novavax) Childhood experiences and vaccine hesitancy (BMJ Open) Fourth vaccine dose in Israel (medRxiv) Antibodies and antivirals vs Omicron (NEJM) Paxlovid and Omicron (Pfizer) Multiple factors and PASC (Cell) Internship at Parasites Without Borders (pdf) 28:47 Letters read on TWiV 862 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]