TWiV reviews the genetic characterization of a new strain of type 2 oral polio vaccine and its implications for eradication, and how a polymorphism in humans comprising a single amino acid change in an antibody molecule regulates vaccine elicitation of broadly neutralizing antibodies against influenza virus HA. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Characterization of novel OPV2 from humans (MMWR) Engineering nOPV2 (TWiV 756) Genome sequence of Rockland County NY OPV2 isolate (Genbank) Allelic polymorphism and vaccine induction of influenza virus bnAbs (Immunity) Letters read on TWiV 931 Timestamps by Jolene. Thanks! Weekly Picks Dickson - Small groups: 1.  Miles Davis Quintet. Signature album: Kind Of Blue. Signature song: So What. Brianne - World Excel Championships Kathy - Lyre bird background and video Alan – The Kissing Bug, by Daisy Hernandez Vincent -Five top detective fiction writers. #1 Martin Beck by Maj Sjöwall and Per Wahlöö Listener Picks John – Fevers, Feuds and Diamonds: Ebola and the Ravages of History by Paul Farmer Carol – The Social Dilemma Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]