In his weekly clinical update Dr. Griffin discusses vaccine effectiveness against influenza illness in children, clinical manifestations of infection with poliovirus, spike protein-independent attenuation of SARS-CoV-2 Omicron variant in laboratory mice, concordance of SARS-CoV-2 results in self-collected nasal swabs vs swabs collected by health care workers in children and adolescents, probable animal-to-human transmission of SARS-CoV-2 causing a pet shop-related outbreak, laboratory-confirmed COVID-19–associated hospitalizations among adults during BA.2 variant, SARS-CoV-2 specific T-cells and antibodies, Nirmatrelvir use and outcomes during the Omicron surge, real-world effectiveness of early Molnupiravir or Nirmatrelvir–ritonavir in hospitalized patients, and distinguishing features of long COVID. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Vaccine effectiveness against Influenza illness in children (CID) Clinical manifestations of infection with Polio (JAMA) Characteristics of deaths among fully vaccinated persons with Coronavirus (CID) Spike protein attenuation of Omicron Variant in lab mice (Cell Reports) Concordance of SARS-CoV-2 results in nasal swabs self-collected vs healthcare collected (JAMA) Probable animal-to-human transmission of Sars-Cov-2 (CID) PAXLOVID patient eligibility screening checklist (FDA) Remdesivir fact sheet for providers (Veklury)  Bebtelovimab fact sheet for providers (FDA) COVID-19–associated hospitalizations among adults during BA.2 variant (CDC) Sars-Cov-2 specific T-cells and antibodies (CID) Nirmatrelvir use and outcomes during the Omicron surge (NEJM) Effectiveness of early Molnupiravir or Nirmatrelvir–Ritonavir in hospitalized patients (The Lancet) Distinguishing features of long COVID (medRxiv) Unexplained post-acute infection syndromes (Nature Med) Contribute to Floating Doctors fundraiser at PWB Dr. Griffin’s treatment guide (pdf) Letters read on TWiV 932 Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]