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Join us for a deep dive into the molecular science of anti aging with the brilliant mind behind the innovative brand MDAiRE , Dr Stefani Kappel MD. This episode focuses on the uniquely intricate science of aging down to the major molecular pathways involved including those targeted by the MDAiRE range of products. Dr Kappel talks to us all about the details of ARE and how she utilized the details of understanding its mechanism of action while creating her incredibly efficacious brand. 

ARE is an acronym for an important signal transduction pathway in the skin. It stands for the Antioxidant Response Element (ARE). The “i” in science represents “the induction of". Hence AIRE represents the activation of this powerful anti-aging pathway. Inducing this key anti-aging pathway results in the transcription and translation of protective genes that play a major role in the anti-aging process. Activation of the AIRE pathway protects skin cells from oxidative stress which remains one of the best etiologies to explain the mechanism of aging.  

Dr. Kappel is a board certified, and double fellowship trained Dermatologist and Mohs Micrographic Surgeon with an active practice in Newport Beach California. She has over 15 years of experience in practicing Dermatology and studying the skin. She has a Medical Degree from UC Irvine and completed her residency in Dermatology at UCLA. Upon completing her residency, she joined the full-time faculty at UCLA as a Clinical Instructor and Professor in Dermatology and Dermatologic Surgery. She then went on to complete advanced fellowship training in Dermatologic Surgery at UC Davis and Cosmetic Dermatology at the Laser and Skin Surgery Center of Northern California with world-renowned expert, Dr. Suzanne Kilmer. After fellowship, she was appointed the Director of Dermatologic Surgery at the Laser & Skin Surgery Center of Northern California where she has remained active in clinical trials and has been on the forefront of the latest advances in aesthetics and dermatology.

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