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Jennifer Li, Partner at Andreessen Horowitz (a16z), breaks down why the firm allocated $1.7 billion of its latest $15 billion fund specifically toward AI infrastructure, and what she's betting on next.
Jennifer has backed ElevenLabs from Series A all the way through Series D, watching it grow to an $11 billion valuation. In this episode, she explains what she saw in voice AI before anyone else did, what makes a founder worth backing regardless of the tech, and why the next wave of AI infrastructure is being rebuilt from the ground up.
In this episode:
- Why a16z bet $1.7B on AI infrastructure (and why now)
- The shift from cloud to AI-native infrastructure: storage, compute, orchestration, memory
- How ElevenLabs crossed the uncanny valley in synthetic voice
- Voice agents as the first AI category to truly scale in the enterprise
- What "king-making" in AI go-to-market actually looks like
- The traits that made Jennifer write a check for ElevenLabs on founder conviction alone
- Open source vs. frontier models: what 2027 looks like
- Why world models and vision language models are the next unlock
- AI and human creativity: why directors and authors won't be replaced
- How a 1-2 person studio can now make a full movie
Host: Sophie Buonassisi, SVP Marketing at GTMnow
https://www.linkedin.com/in/sophiebuonassisi
Guest: Jennifer Li, General Partner at Andreessen Horowitz
https://www.linkedin.com/in/jenniferhli/
https://x.com/JenniferHli
Connect with Max:
https://x.com/hackitmax
https://www.linkedin.com/in/maxaltschuler
Connect with Paul:
https://x.com/PaulGTM
https://www.linkedin.com/in/paulsirving
Timestamps:
0:00 - Cold open
1:06 - Max & Paul intro: are we in a bubble?
1:46 - AI vs. dot-com era: the key differences
4:55 - B2B SaaS disruption and value destruction (Thoma Bravo / Medallia)
6:39 - Intercom / Finn: crossing the chasm from legacy to AI-native
8:08 - Introducing Jennifer Lee, a16z General Partner
8:31 - Paul's key takeaway: the distribution era
9:41 - Why speed to default brand has never mattered more
11:33 - The ElevenLabs story: a16z led Series A, B, and C
12:02 - Why the seed strategy still works
13:37 - What the best founders do differently with model capabilities
15:58 - Jennifer Lee joins: why a16z raised $1.7B for infrastructure
16:22 - What existing infrastructure is being rebuilt for AI
19:19 - Specific areas a16z is focused on: models, storage, dev tools, security
20:35 - 90%+ of code now written by agents
21:52 - What Jennifer saw early in the 11 Labs / voice AI space
25:19 - Go-to-market in AI infrastructure: what's working
27:29 - Becoming the default brand: the "Kleenex effect" in AI
28:37 - What makes a founder worth backing on conviction alone
30:48 - Predictions for 2026/2027: open source catching up fast
31:39 - Most exciting new modalities: world models and vision language models
32:07 - AI and human creativity: can they coexist?
34:42 - What's blocking the creative AI future
36:05 - "The best ideas live in the graveyard"
36:57 - Closing advice: make AI tools your friends
Visit us on: https://gtmnow.com
Follow us on LinkedIn: https://www.linkedin.com/company/gtmnow
Follow us on X (Twitter): https://x.com/GTMnow_
Follow us on
The GTMnow Podcast
The GTMnow Podcast is a weekly podcast featuring interviews with the top 1% GTM executives, VCs, and founders. Conversations reveal the unshared details behind how they have grown companies, and the go-to-market strategies responsible for shaping that growth.
Visit gtmnow.com for more episodes and other interesting content.
By GTMnow4.6
149149 ratings
Jennifer Li, Partner at Andreessen Horowitz (a16z), breaks down why the firm allocated $1.7 billion of its latest $15 billion fund specifically toward AI infrastructure, and what she's betting on next.
Jennifer has backed ElevenLabs from Series A all the way through Series D, watching it grow to an $11 billion valuation. In this episode, she explains what she saw in voice AI before anyone else did, what makes a founder worth backing regardless of the tech, and why the next wave of AI infrastructure is being rebuilt from the ground up.
In this episode:
- Why a16z bet $1.7B on AI infrastructure (and why now)
- The shift from cloud to AI-native infrastructure: storage, compute, orchestration, memory
- How ElevenLabs crossed the uncanny valley in synthetic voice
- Voice agents as the first AI category to truly scale in the enterprise
- What "king-making" in AI go-to-market actually looks like
- The traits that made Jennifer write a check for ElevenLabs on founder conviction alone
- Open source vs. frontier models: what 2027 looks like
- Why world models and vision language models are the next unlock
- AI and human creativity: why directors and authors won't be replaced
- How a 1-2 person studio can now make a full movie
Host: Sophie Buonassisi, SVP Marketing at GTMnow
https://www.linkedin.com/in/sophiebuonassisi
Guest: Jennifer Li, General Partner at Andreessen Horowitz
https://www.linkedin.com/in/jenniferhli/
https://x.com/JenniferHli
Connect with Max:
https://x.com/hackitmax
https://www.linkedin.com/in/maxaltschuler
Connect with Paul:
https://x.com/PaulGTM
https://www.linkedin.com/in/paulsirving
Timestamps:
0:00 - Cold open
1:06 - Max & Paul intro: are we in a bubble?
1:46 - AI vs. dot-com era: the key differences
4:55 - B2B SaaS disruption and value destruction (Thoma Bravo / Medallia)
6:39 - Intercom / Finn: crossing the chasm from legacy to AI-native
8:08 - Introducing Jennifer Lee, a16z General Partner
8:31 - Paul's key takeaway: the distribution era
9:41 - Why speed to default brand has never mattered more
11:33 - The ElevenLabs story: a16z led Series A, B, and C
12:02 - Why the seed strategy still works
13:37 - What the best founders do differently with model capabilities
15:58 - Jennifer Lee joins: why a16z raised $1.7B for infrastructure
16:22 - What existing infrastructure is being rebuilt for AI
19:19 - Specific areas a16z is focused on: models, storage, dev tools, security
20:35 - 90%+ of code now written by agents
21:52 - What Jennifer saw early in the 11 Labs / voice AI space
25:19 - Go-to-market in AI infrastructure: what's working
27:29 - Becoming the default brand: the "Kleenex effect" in AI
28:37 - What makes a founder worth backing on conviction alone
30:48 - Predictions for 2026/2027: open source catching up fast
31:39 - Most exciting new modalities: world models and vision language models
32:07 - AI and human creativity: can they coexist?
34:42 - What's blocking the creative AI future
36:05 - "The best ideas live in the graveyard"
36:57 - Closing advice: make AI tools your friends
Visit us on: https://gtmnow.com
Follow us on LinkedIn: https://www.linkedin.com/company/gtmnow
Follow us on X (Twitter): https://x.com/GTMnow_
Follow us on
The GTMnow Podcast
The GTMnow Podcast is a weekly podcast featuring interviews with the top 1% GTM executives, VCs, and founders. Conversations reveal the unshared details behind how they have grown companies, and the go-to-market strategies responsible for shaping that growth.
Visit gtmnow.com for more episodes and other interesting content.

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