Oncologist and epidemiologist Vinay Prasad argues that too many very expensive drugs get approved by the FDA that have very limited impact on the lives of patients. Prasad explains the incentives that distort the current system. The general problem, he explains to EconTalk host Russ Roberts, is the death of duty--too many players in the health care landscape and elsewhere stay quiet or do the wrong thing in order to serve themselves.

Vinay Prasad on Pharmaceuticals, the FDA, and the Death of Duty

EconTalk: Conversations for the Curious is an award-winning weekly podcast hosted by Russ Roberts of Shalem College in Jerusalem and Stanford's Hoover Institution. The eclectic guest list includes authors, doctors, psychologists, historians, philosophers, economists, and more. Learn how the health care system really works, the serenity that comes from humility, the challenge of interpreting data, how potato chips are made, what it's like to run an upscale Manhattan restaurant, what caused the 2008 financial crisis, the nature of consciousness, and more. EconTalk has been taking the Monday out of Mondays since 2006.  All 900+ episodes are available in the archive. Go to EconTalk.org for transcripts, related resources, and comments.

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Economist and social critic Glenn Loury talks about his memoir, Late Admissions, with EconTalk's Russ Roberts. In a wide-ranging and blunt conversation, Loury discusses his childhood, his at-times brilliant academic work, his roller-coaster ideological journey, and his personal flaws as a drug addict and imperfect husband. This is a rich conversation about academic life, race in America, and the challenges of self-control.

Glenn Loury Tells All

What does it mean to live Constitutionally in the year 2024? For a start, it means getting off social media. It also means swapping a quill pen for your keyboard, and candlelight for electricity. And don't forget the tricorn hat and musket--though maybe skip the boiled mutton. Join author A.J. Jacobs as he deep-dives with EconTalk's Russ Roberts into the centuries-old principles of the U.S. Constitution and tries to apply them to the current day. Topics include the original conceptions of our most cherished amendments, the office of the President, and the Supreme Court, and an explanation of how one can be an originalist and still believe in gender equity. Jacobs also shares his family's experience writing its own constitution, and explains why his research made him more optimistic about the future of American democracy.

Living with the Constitution (with A.J. Jacobs)

The favorite EconTalk episodes for host Russ Roberts are when he and his guest have an unusually powerful connection such as his recent episode with Charles Duhigg, and the ones where he learns something mind-blowing, like Adam Mastroianni’s insight that you can’t reach the brain through the ears. Listen as Russ explains how he chooses guests, and why EconTalk has evolved to focus on things other than economics. He also shares listeners' favorite conversations from 2023, and tells a story that shows the challenges—and opportunities—of applying EconTalk’s lessons to our personal lives.

The Top EconTalk Conversations of 2023 (with Russ Roberts)

Would an AI simulation of your dead loved one be a blessing or an abomination? And if you knew that after your own death, your loved ones would create a simulation of you, how would that knowledge change the way you choose to live today? These are some of the questions psychologist Paul Bloom discusses with EconTalk's Russ Roberts as we stand on the threshold of digital immortality.

Seeking Immortality (with Paul Bloom)

If the Wright Brothers could have used AI to guide their decision making, it's almost certain they would never have gotten off the ground. That's because, points out Teppo Felin of Utah State University and Oxford, all the evidence said human flight was impossible. So how and why did the Wrights persevere? Felin explains that the human ability to ignore existing data and evidence is not only our Achilles heel, but also one of our superpowers. Topics include the problems inherent in modeling our brains after computers, and the value of not only data-driven prediction, but also belief-driven experimentation.

Vinay Prasad on Pharmaceuticals, the FDA, and the Death of Duty

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