In this episode, hosts Amy and Nikki dive into a controversial discussion about folic acid and folate supplements, challenging common beliefs held within the functional medicine community. They explore the role of folate in human health, debunk myths around the MTHFR gene mutation, and emphasize the potential benefits of folic acid. 

They discuss various factors that affect folate absorption, such as zinc and riboflavin dependency, and highlight the importance of balanced nutrition over high-dose supplements. The episode also touches on the interconnections between different nutrients and their impact on overall health, encouraging listeners to adopt a holistic approach to their dietary needs.

00:00 Introduction and Hot Take on Folic Acid
00:50 Understanding MTHFR and Genetic SNPs
02:09 The Overemphasis on MTHFR in Functional Medicine
04:02 Personal Experiences with Genetic Testing
06:25 The Importance of B Vitamins for Everyone
08:12 Folic Acid vs. Folate: Bioavailability and Fortification
09:45 Dietary Sources of Folate and Nutrient Deficiencies
15:40 Microbiome's Role in Folate Production
20:16 Folate's Impact on Gut Health and Cell Division
24:40 The Role of Folate in Neurotransmitter Production
25:06 Folate and Mental Health: Real-Life Experiences
25:38 The Importance of Methylation and Folate
26:35 Debunking Folate Myths with Chris Masterjohn
27:56 The Body's Natural Methyl Donors
31:19 Folate, Choline, and Gut Health
32:05 Folate and Histamine Intolerance
33:41 The SIBO Diagnosis Debate
39:15 Folate Absorption and Nutrient Interactions
43:28 The Risks of High-Dose Folate Supplements
49:14 Conclusion and Next Steps: Vitamin B12

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Nikki's Info:
- Youtube Channel: https://www.youtube.com/c/TriangleHolisticGutHealth
- Instagram: @Gut.Microbiome.Queen
- FODMAP Freedom in 90 Days: https://www.fodmapfreedom.com/enroll
- Private Appts: https://infinityholistichealth.com/

Amy's Info:
- Practice: https://sibodiaries.com/
- Instagram: @Amy_Hollenkamp_RD