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Today I’m sharing my conversation with Dr. David Nutt—Edmond J. Safra Professor of Neuropsychopharmacology at Imperial College London—one of the most influential and outspoken figures in modern psychiatric research and drug policy. It’s a wide-ranging chat about addiction science, pharmacology, and the past and future of medication development—including his current focus on psychedelics.

In particular, we turn to the intellectual foundations of addiction science and focus on one of Dave’s core arguments: the field went down the wrong path by treating dopamine as a master explanation for addiction.

Check out my Substack post for more about Dr. Nutt's work

Find him on YouTube, Instagram, Bluesky, Twitter/X, and at the charity he founded, DrugScience.org.uk. 

Sign up for my newsletter and immediately receive my own free guide to the many pathways to recovery, as well as regular updates on new interviews, material, and other writings.